دورية أكاديمية
Effectiveness of the piperine-supplemented Curcuma longa L. in metabolic control of patients with type 2 diabetes: a randomised double-blind placebo-controlled clinical trial.
| العنوان: | Effectiveness of the piperine-supplemented Curcuma longa L. in metabolic control of patients with type 2 diabetes: a randomised double-blind placebo-controlled clinical trial. |
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| المؤلفون: | Neta JFF; Oswaldo Cruz Foundation, Eusébio, Brazil., Veras VS; Health Sciences Institute, University for International Integration of the Afro Brazilian Lusophony, Redenção, Brazil., Sousa DF; Health Sciences Institute, University for International Integration of the Afro Brazilian Lusophony, Redenção, Brazil., Cunha MDCDSO; Department of Nursing, State University of Ceará, Fortaleza, Brazil., Queiroz MVO; Department of Nursing, State University of Ceará, Fortaleza, Brazil., Neto JCGL; Department of Nursing, Federal University of Piauí, Floriano, Brazil., Damasceno MMC; Department of Nursing, Dentist and Pharmacy Faculty, Federal University of Ceará, Fortaleza, Brazil., Araújo MFM; Oswaldo Cruz Foundation, Eusébio, Brazil., Freitas RWJF; Oswaldo Cruz Foundation, Eusébio, Brazil. |
| المصدر: | International journal of food sciences and nutrition [Int J Food Sci Nutr] 2021 Nov; Vol. 72 (7), pp. 968-977. Date of Electronic Publication: 2021 Feb 14. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 9432922 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1465-3478 (Electronic) Linking ISSN: 09637486 NLM ISO Abbreviation: Int J Food Sci Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: Basingstoke, UK : Scientific and Medical Division, Macmillan Press, 1992- |
| مواضيع طبية MeSH: | Curcuma* , Diabetes Mellitus, Type 2*/drug therapy, Alkaloids/*therapeutic use , Benzodioxoles/*therapeutic use , Piperidines/*therapeutic use , Plant Preparations/*therapeutic use , Polyunsaturated Alkamides/*therapeutic use, Double-Blind Method ; Humans |
| مستخلص: | There is robust evidence of using Curcuma longa L. in reducing metabolic levels in people with diabetes. This study analysed the effectiveness of Curcuma longa L. in the metabolic control of patients with type 2 diabetes in Brazil. A randomised double-blind placebo-controlled clinical trial was conducted with 71 participants divided into a Curcuma longa L. group (500 mg/day with piperine 5 mg) and a placebo group, for 120 days. Anthropometric, clinical and biochemical variables were evaluated at baseline, 60 and 120 days after the beginning of the intervention. Paired and independent Student's t -test and chi-square test were used for statistical analysis. The curcuma group presented a significantly decreased glycaemia ( p =.013), glycated haemoglobin ( p =.015), HOMA index ( p =.037) and triglycerides (TGs) ( p =.002). The use of piperine-added Curcuma longa L. was effective in the glycaemic and TG control of patients with type 2 diabetes. |
| فهرسة مساهمة: | Keywords: Type 2 diabetes mellitus; curcuminoids; glucose; phytotherapy; piperine; primary healthcare |
| المشرفين على المادة: | 0 (Alkaloids) 0 (Benzodioxoles) 0 (Piperidines) 0 (Plant Preparations) 0 (Polyunsaturated Alkamides) U71XL721QK (piperine) |
| تواريخ الأحداث: | Date Created: 20210215 Date Completed: 20211124 Latest Revision: 20211124 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/09637486.2021.1885015 |
| PMID: | 33586583 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1465-3478 |
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| DOI: | 10.1080/09637486.2021.1885015 |