دورية أكاديمية
Effects of Green Banana Biomass ( Musa spp. ) on Laboratory Parameters of Animal Models of Wistar Mice under Hyperlipidic Diet.
| العنوان: | Effects of Green Banana Biomass ( Musa spp. ) on Laboratory Parameters of Animal Models of Wistar Mice under Hyperlipidic Diet. |
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| المؤلفون: | Lousek NF; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Santos NC; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Dourado MCM; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Pontieri FM; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Teófilo MNG; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Castro FS; Health Sciences, Faculty of the Military Police, Pontifical Catholic University of Goias, Goiânia, Brazil., Costa SHN; Health Sciences, Faculty of the Military Police, Pontifical Catholic University of Goias, Goiânia, Brazil., Blanch GT; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Borges AF; Health Sciences, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil., Gomes CM; Health Sciences, Faculty of the Military Police, Pontifical Catholic University of Goias, Goiânia, Brazil. |
| المصدر: | Journal of the American College of Nutrition [J Am Coll Nutr] 2021 Jul; Vol. 40 (5), pp. 472-477. Date of Electronic Publication: 2021 Feb 19. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American College of Nutrition Country of Publication: United States NLM ID: 8215879 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-1087 (Electronic) Linking ISSN: 07315724 NLM ISO Abbreviation: J Am Coll Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, NY : American College of Nutrition Original Publication: New York : Alan R. Liss, c1982- |
| مواضيع طبية MeSH: | Musa*, Animals ; Biomass ; Diet ; Laboratories ; Mice ; Models, Animal ; Rats ; Rats, Wistar |
| مستخلص: | Aim: Analyze the effects of green banana biomass ( Musa spp. ) on the biochemical parameters in Wistar male rats under standard and hyperlipidic diet. Methods: Ethical approval for this study was obtained from Ethics Committee on the Use of Animals CEUA - PUC-GO and consisted in the division of 32 rats in 4 differentiated groups according to their diet (standard - CT; standard with green banana biomass - CTBM; hyperlipidic - HL and hyperlipidic with green banana biomass - HLBM). Through 8 weeks animals were weighted and their glycemia were measured. After this period, they were euthanized and biological material was collected to evaluate the biochemical parameters, which analysis used the ANOVA test. Results: The weekly evaluation confirmed that the efficacy of the hyperlipidic model since the final weight was bigger in the HL group in comparison with the CT group, from the sixth to the eighth week. It was also possible to observe that the CTBM group had a smaller weight compared to the CT group. Besides, the measurement of glycemia, high-density lipoprotein, triglycerides, alanine aminotransferase, aspartate aminotransferase, serum total bilirubin, direct bilirubin, alkaline phosphatase, urea, serum creatine, uric acid, calcium, phosphor, magnesium and the hematological parameters from the 8 animal of each group were compared by the ANOVA test without any significative difference ( p < 0.05) in the comparisons. Conclusions: This study it did not demonstrate significative changes of the green banana biomass on the observed laboratory parameters during the 8 weeks in comparison to the standard group, indicating an absence of interference of the probiotics in the laboratory parameters on the hyperlipidic model during the analyzed period. Therefore, it is necessary an evaluation of its efficacy in obesity treatment in longer studies with molecular parameters. |
| فهرسة مساهمة: | Keywords: Green banana biomass; Wistar mice; hyperlipidic diet; obesity; prebiotics |
| تواريخ الأحداث: | Date Created: 20210219 Date Completed: 20211124 Latest Revision: 20211124 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/07315724.2020.1792811 |
| PMID: | 33606598 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1541-1087 |
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| DOI: | 10.1080/07315724.2020.1792811 |