دورية أكاديمية
Improving surgical outcome with electric source imaging and high field magnetic resonance imaging.
| العنوان: | Improving surgical outcome with electric source imaging and high field magnetic resonance imaging. |
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| المؤلفون: | Saute RL; Department of Neurosciences and Behavioral Sciences, Ribeirao Preto Medical School, University of Sao Paulo, Brazil., Peixoto-Santos JE; Discipline of Neuroscience, Department of Neurology and Neurosurgery, Paulista School of Medicine, Unifesp, Brazil., Velasco TR; Department of Neurosciences and Behavioral Sciences, Ribeirao Preto Medical School, University of Sao Paulo, Brazil., Leite JP; Department of Neurosciences and Behavioral Sciences, Ribeirao Preto Medical School, University of Sao Paulo, Brazil. Electronic address: jpleite@fmrp.usp.br. |
| المصدر: | Seizure [Seizure] 2021 Aug; Vol. 90, pp. 145-154. Date of Electronic Publication: 2021 Feb 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9306979 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2688 (Electronic) Linking ISSN: 10591311 NLM ISO Abbreviation: Seizure Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Elsevier Original Publication: London : Baillière Tindall, c1992- |
| مواضيع طبية MeSH: | Brain*/diagnostic imaging , Brain*/surgery , Epilepsies, Partial*, Electroencephalography ; Humans ; Magnetic Resonance Imaging ; Treatment Outcome |
| مستخلص: | While most patients with focal epilepsy present with clear structural abnormalities on standard, 1.5 or 3 T MRI, some patients are MRI-negative. For those, quantitative MRI techniques, such as volumetry, voxel-based morphometry, and relaxation time measurements can aid in finding the epileptogenic focus. High-field MRI, just recently approved for clinical use by the FDA, increases the resolution and, in several publications, was shown to improve the detection of focal cortical dysplasias and mild cortical malformations. For those cases without any tissue abnormality in neuroimaging, even at 7 T, scalp EEG alone is insufficient to delimitate the epileptogenic zone. They may benefit from the use of high-density EEG, in which the increased number of electrodes helps improve spatial sampling. The spatial resolution of even low-density EEG can benefit from electric source imaging techniques, which map the source of the recorded abnormal activity, such as interictal epileptiform discharges, focal slowing, and ictal rhythm. These EEG techniques help localize the irritative, functional deficit, and seizure-onset zone, to better estimate the epileptogenic zone. Combining those technologies allows several drug-resistant cases to be submitted to surgery, increasing the odds of seizure freedom and providing a must needed hope for patients with epilepsy. (Copyright © 2021. Published by Elsevier Ltd.) |
| فهرسة مساهمة: | Keywords: Drug-resistant epilepsy; Electric source imaging; High-density EEG; High-field MRI; MRI-negative |
| تواريخ الأحداث: | Date Created: 20210220 Date Completed: 20210811 Latest Revision: 20210811 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.seizure.2021.02.006 |
| PMID: | 33608134 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1532-2688 |
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| DOI: | 10.1016/j.seizure.2021.02.006 |