دورية أكاديمية
Spirulina sp. LEB 18-extracted phycocyanin: Effects on liposomes' physicochemical parameters and correlation with antiradical/antioxidant properties.
| العنوان: | Spirulina sp. LEB 18-extracted phycocyanin: Effects on liposomes' physicochemical parameters and correlation with antiradical/antioxidant properties. |
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| المؤلفون: | de Moraes Nogueira AO; Grupo de Investigação em Interações Moleculares em Membranas, Programa de Pós-Graduação em Química Tecnológica e Ambiental, Brazil; Laboratório de Biotecnologia, Brazil., Felipe Kokuszi LT; Grupo de Investigação em Interações Moleculares em Membranas, Programa de Pós-Graduação em Química Tecnológica e Ambiental, Brazil., Poester Cordeiro A; Laboratório de Biotecnologia, Brazil., Ziebell Salgado H; Laboratório de Biotecnologia, Brazil., Costa JAV; Laboratório de Engenharia Bioquímica, Escola de Química e Alimentos, Universidade Federal do Rio Grande, Av. Itália, km 8, Campus Carreiros, 96203-900, Rio Grande, RS, Brazil., Santos LO; Laboratório de Biotecnologia, Brazil., de Lima VR; Grupo de Investigação em Interações Moleculares em Membranas, Programa de Pós-Graduação em Química Tecnológica e Ambiental, Brazil. Electronic address: vanialima@furg.br. |
| المصدر: | Chemistry and physics of lipids [Chem Phys Lipids] 2021 May; Vol. 236, pp. 105064. Date of Electronic Publication: 2021 Feb 17. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Ireland Ltd Country of Publication: Ireland NLM ID: 0067206 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2941 (Electronic) Linking ISSN: 00093084 NLM ISO Abbreviation: Chem Phys Lipids Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Limerick : Elsevier Science Ireland Ltd Original Publication: Amsterdam. |
| مواضيع طبية MeSH: | Antioxidants/*pharmacology , Phycocyanin/*pharmacology , Spirulina/*chemistry, Antioxidants/chemistry ; Antioxidants/isolation & purification ; Biphenyl Compounds/antagonists & inhibitors ; Fluorescence Recovery After Photobleaching ; Liposomes/chemistry ; Phycocyanin/chemistry ; Phycocyanin/isolation & purification ; Picrates/antagonists & inhibitors |
| مستخلص: | This study describes the physicochemical properties of soybean asolectin (ASO) liposomes loaded with phycocyanin (Phy) extracted from Spirulina sp. LEB 18. The effects of Phy in the liposomes' properties were investigated by Fourier transform infrared spectroscopy (FTIR), 1 H and 31 P nuclear magnetic resonance (NMR), zeta (ζ)-potential, dynamic light scattering (DLS) and ultraviolet-visible (UV-vis) techniques. Phy restricted the motion of ASO polar and interface groups and disrupted the package arrangement of the lipid hydrophobic regions, as a likely effect of dipolar and π interactions related to its amino acid residues and pyrrole portions. These interactions were correlated to antiradical/antioxidant Phy responses obtained by 2,2-diphenyl-1-picrylhidrazil (DPPH) assay, thiobarbituric acid reactive substances (TBARS) and ferric reducing antioxidant power (FRAP) methods, and discussed to bring new chemical perspectives about Phy-loaded liposomes-related nutraceutical applications in inflammatory and viral infection processes. (Copyright © 2021 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antioxidant; Antiradical; Liposomes; Phycocyanin; Spectroscopy |
| المشرفين على المادة: | 0 (Antioxidants) 0 (Biphenyl Compounds) 0 (Liposomes) 0 (Picrates) 11016-15-2 (Phycocyanin) DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl) |
| تواريخ الأحداث: | Date Created: 20210220 Date Completed: 20211104 Latest Revision: 20211104 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.chemphyslip.2021.105064 |
| PMID: | 33609502 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-2941 |
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| DOI: | 10.1016/j.chemphyslip.2021.105064 |