دورية أكاديمية
Four new isoflavones from Derris scandens and their in vitro antiproliferative effects.
| العنوان: | Four new isoflavones from Derris scandens and their in vitro antiproliferative effects. |
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| المؤلفون: | Ito C; Faculty of Pharmacy, Meijo University, Nagoya, Aichi, Japan., Matsui T; Faculty of Pharmacy, Meijo University, Nagoya, Aichi, Japan.; Department of Physiology, Aichi Medical University, Nagakute, Aichi, Japan., Miyabe K; Faculty of Pharmacy, Meijo University, Nagoya, Aichi, Japan., Hasan CM; Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh., Rashid MA; Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh., Itoigawa M; School of Sports and Health Science, Tokai Gakuen University, Miyoshi, Aichi, Japan. |
| المصدر: | Natural product research [Nat Prod Res] 2022 Mar; Vol. 36 (6), pp. 1448-1453. Date of Electronic Publication: 2021 Feb 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Derris* , Isoflavones*/pharmacology, Cell Survival ; Membrane Potential, Mitochondrial ; Plant Extracts |
| مستخلص: | Four new compounds (derriscandenon D ( 1 ), E ( 2 ), F ( 3 ), G ( 4 )) and six known isoflavones (warangalone ( 5 ), millewanin E ( 6 ), rhynedlin A ( 7 ), 6,8-diprenylgenistein ( 8 ), isolupalbigenin ( 9 ), isoscandinone ( 10 )) were isolated from the acetone extract of the branches of Derris scandens . These compounds were assayed for cell viability using the human lung carcinoma cell line A549, colorectal carcinoma cell line Colo205, epidermoid carcinoma cell line KB, the human acute lymphoblastic leukaemia cell line NALM-6, and human dermal fibroblasts. Compounds 2 and 3 significantly decreased the viability of KB cells, with IC |
| فهرسة مساهمة: | Keywords: Derris scandens; Leguminosae; cell viability; isoflavone; mitochondrial membrane potential |
| المشرفين على المادة: | 0 (Isoflavones) 0 (Plant Extracts) |
| تواريخ الأحداث: | Date Created: 20210224 Date Completed: 20220310 Latest Revision: 20220311 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/14786419.2021.1888290 |
| PMID: | 33624558 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2021.1888290 |