دورية أكاديمية
أعرض في EDS

The Magnitude of Neonatal Mortality and Its Predictors in Ethiopia: A Systematic Review and Meta-Analysis.

التفاصيل البيبلوغرافية
العنوان: The Magnitude of Neonatal Mortality and Its Predictors in Ethiopia: A Systematic Review and Meta-Analysis.
المؤلفون: Aynalem YA; College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia., Shiferaw WS; College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia., Akalu TY; College of Health Science, Debre Markos University, Debre Markos, Ethiopia., Dargie A; College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia., Assefa HK; College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia., Habtewold TD; College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia.; Department of Epidemiology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.
المصدر: International journal of pediatrics [Int J Pediatr] 2021 Feb 17; Vol. 2021, pp. 7478108. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: Egypt NLM ID: 101517077 Publication Model: eCollection Cited Medium: Print ISSN: 1687-9740 (Print) Linking ISSN: 16879740 NLM ISO Abbreviation: Int J Pediatr Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Cairo] : Hindawi Pub. Corp.
مستخلص: Background: Although neonatal death is a global burden, it is the highest in sub-Saharan African countries such as Ethiopia. Moreover, there is disparity in the prevalence and associated factors of studies. Therefore, this study was aimed at providing pooled national prevalence and predictors of neonatal mortality in Ethiopia.
Methods: The following databases were systematically explored to search for articles: Boolean operator, Cochrane Library, PubMed, EMBASE, Hinari, and Google Scholar. Selection, screening, reviewing, and data extraction were done by two reviewers independently using Microsoft Excel spreadsheet. The modified Newcastle-Ottawa Scale (NOS) and the Joanna Briggs Institute Prevalence Critical Appraisal tools were used to assess the quality of evidence. All studies conducted in Ethiopia and reporting the prevalence and predictors of neonatal mortality were included. Data were extracted using Microsoft Excel spreadsheet software and imported into Stata version 14s for further analysis. Publication bias was checked using funnel plots and Egger's and Begg's tests. Heterogeneity was also checked by Higgins's method. A random effects meta-analysis model with 95% confidence interval was computed to estimate the pooled effect size (i.e., prevalence and odds ratio). Moreover, subgroup analysis based on region, sample size, and study design was done.
Results: After reviewing 88 studies, 12 studies fulfilled the inclusion criteria and were included in the meta-analysis. Pooled national prevalence of neonatal mortality in Ethiopia was 16.3% (95% CI: 12.1, 20.6, I 2 = 98.8%). The subgroup analysis indicated that the highest prevalence was observed in the Amhara region, 20.3% (95% CI: 9.6, 31.1), followed by Oromia, 18.8% (95% CI: 11.9, 49.4). Gestational age [AOR: 1.32 (95% CI: 1.07, 1.58)], neonatal sepsis [AOR: 1.23 (95% CI: 1.05, 1.4)], respiratory distress syndromes (RDS) [AOR: 1.18 (95% CI: 0.87, 1.49)], and place of residency [AOR: 1.93 (95% CI: 1.13, 2.73)] were the most important predictors.
Conclusions: Neonatal mortality in Ethiopia was significantly decreased. There was evidence that neonatal sepsis, gestational age, and place of residency were the significant predictors. RDS were also a main predictor of mortality even if not statistically significant. We strongly recommended that health care workers should give a priority for preterm neonates with diagnosis with sepsis and RDS.
Competing Interests: The authors declare that they have no competing interests.
(Copyright © 2021 Yared Asmare Aynalem et al.)
References: BMC Res Notes. 2018 Dec 6;11(1):867. (PMID: 30522518)
BMC Pregnancy Childbirth. 2019 Feb 28;19(1):83. (PMID: 30819143)
BMC Public Health. 2013 May 17;13:483. (PMID: 23683315)
BMC Nurs. 2016 Aug 05;15:48. (PMID: 27499702)
Front Public Health. 2015 Oct 07;3:225. (PMID: 26501049)
PLoS One. 2014 Sep 18;9(9):e107184. (PMID: 25232842)
Ital J Pediatr. 2019 Jan 7;45(1):4. (PMID: 30616641)
PLoS One. 2016 Jan 25;11(1):e0147601. (PMID: 26808317)
Int J Health Policy Manag. 2014 Aug 13;3(3):123-8. (PMID: 25197676)
BMC Pregnancy Childbirth. 2014 Feb 27;14:90. (PMID: 24576205)
BMC Public Health. 2018 Jul 18;18(1):888. (PMID: 30021557)
Contemp Clin Trials. 2007 Feb;28(2):105-14. (PMID: 16807131)
Ethiop J Health Sci. 2016 Jan;26(1):73-9. (PMID: 26949319)
PLoS One. 2018 Sep 14;13(9):e0203314. (PMID: 30216343)
PLoS One. 2016 Oct 14;11(10):e0164472. (PMID: 27741284)
BMC Public Health. 2013 Feb 23;13:168. (PMID: 23433304)
BMC Pregnancy Childbirth. 2014 Feb 11;14:64. (PMID: 24517305)
Am J Public Health. 1986 Dec;76(12):1416-21. (PMID: 3777288)
J Clin Epidemiol. 2009 Oct;62(10):e1-34. (PMID: 19631507)
WHO South East Asia J Public Health. 2012 Jul-Sep;1(3):239-248. (PMID: 28615550)
Neonatology. 2013;103(4):353-68. (PMID: 23736015)
BMC Pregnancy Childbirth. 2010 Feb 23;10 Suppl 1:S1. (PMID: 20233382)
Bull World Health Organ. 2010 Jan;88(1):31-8. (PMID: 20428351)
Pediatric Health Med Ther. 2017 May 12;8:57-64. (PMID: 29388628)
Med J Islam Repub Iran. 2019 Aug 24;33:87. (PMID: 31696081)
Lancet. 2015 Dec 5;386(10010):2275-86. (PMID: 26361942)
JAMA. 2006 Feb 8;295(6):676-80. (PMID: 16467236)
BMC Public Health. 2017 Jan 11;17(1):62. (PMID: 28077109)
Biomed Res Int. 2019 Jan 13;2019:7919501. (PMID: 30756086)
BMC Pregnancy Childbirth. 2016 Aug 02;16(1):202. (PMID: 27485138)
Lancet. 2013 Jan 19;381(9862):223-34. (PMID: 23158883)
BMJ. 2003 Sep 6;327(7414):557-60. (PMID: 12958120)
تواريخ الأحداث: Date Created: 20210308 Latest Revision: 20220421
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC7906817
DOI: 10.1155/2021/7478108
PMID: 33679995
قاعدة البيانات: MEDLINE
الوصف
تدمد:1687-9740
DOI:10.1155/2021/7478108