دورية أكاديمية
Comparative Study Between Silver Nanoparticles Dressing (SilvrSTAT Gel) and Conventional Dressing in Diabetic Foot Ulcer Healing: A Prospective Randomized Study.
| العنوان: | Comparative Study Between Silver Nanoparticles Dressing (SilvrSTAT Gel) and Conventional Dressing in Diabetic Foot Ulcer Healing: A Prospective Randomized Study. |
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| المؤلفون: | Essa MS; Benha University Hospital, Benha University, Benha, Egypt., Ahmad KS; Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia., Zayed ME; Benha University Hospital, Benha University, Benha, Egypt., Ibrahim SG; Benha University Hospital, Benha University, Benha, Egypt. |
| المصدر: | The international journal of lower extremity wounds [Int J Low Extrem Wounds] 2023 Mar; Vol. 22 (1), pp. 48-55. Date of Electronic Publication: 2021 Mar 09. |
| نوع المنشور: | Randomized Controlled Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Publications Country of Publication: United States NLM ID: 101128359 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-6941 (Electronic) Linking ISSN: 15347346 NLM ISO Abbreviation: Int J Low Extrem Wounds Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Thousand Oaks, CA : Sage Publications, c2002- |
| مواضيع طبية MeSH: | Diabetic Foot*/therapy , Diabetic Foot*/surgery , Metal Nanoparticles* , Burns* , Diabetes Mellitus*, Humans ; Silver ; Prospective Studies ; Bandages |
| مستخلص: | Background: We are trying to evaluate silver nanoparticles' effectiveness (SilvrSTAT Gel) in accelerating healing rate of nonischemic diabetic foot ulcers (DFUs). Methods: This prospective, double-blind, randomized, controlled study includes 80 patients with nonischemic DFUs classified into 2 groups. Group A was subjected to SilvrSTAT Gel dressing, and group B was subjected to conventional dressing (wet-to-moist dressing with or without povidone-iodine). All cases had minimal debridement before treatment. In both groups, all cases were nonischemic after successful revascularization either by bypass surgery or endovascular therapy. Results: The healing rate of the SilvrSTAT group was significantly higher than that of the conventional group. The healing rate per week of the SilvrSTAT group was considerably higher than that of the conventional group ( P < .0001). The rate of complete healing for ulcers in group A was achieved in 22 patients (55%) by the 6th week, while 29 (72.5%), 34 (85%), and 36 (90%) patients were healed entirely by the 8th, 10th, and 12th weeks, respectively. In group B: 20 (50%), 27 (67.5%), and 30 (75%) patients were completeley healed by the 8th, 10th, and 12th weeks, respectively. Conclusions: SilvrSTATGel is effective in the treatment of DFU. |
| فهرسة مساهمة: | Keywords: SilvrSTAT Gel; conventional dressing; foot ulcer; healing; nanoparticles |
| المشرفين على المادة: | 3M4G523W1G (Silver) |
| تواريخ الأحداث: | Date Created: 20210309 Date Completed: 20230203 Latest Revision: 20230203 |
| رمز التحديث: | 20230203 |
| DOI: | 10.1177/1534734620988217 |
| PMID: | 33686887 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1552-6941 |
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| DOI: | 10.1177/1534734620988217 |