دورية أكاديمية
أعرض في EDS

BamA and BamD Are Essential for the Secretion of Trimeric Autotransporter Adhesins.

التفاصيل البيبلوغرافية
العنوان: BamA and BamD Are Essential for the Secretion of Trimeric Autotransporter Adhesins.
المؤلفون: Rooke JL; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom., Icke C; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom., Wells TJ; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.; The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, QLD, Australia., Rossiter AE; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom., Browning DF; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom., Morris FC; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom., Leo JC; Department of Biosciences, Nottingham Trent University, Nottingham, United Kingdom.; Department of Biosciences, University of Oslo, Oslo, Norway., Schütz MS; Institut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum Tübingen, Tübingen, Germany., Autenrieth IB; Institut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum Tübingen, Tübingen, Germany., Cunningham AF; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Linke D; Department of Biosciences, University of Oslo, Oslo, Norway., Henderson IR; Institute for Molecular Bioscience, University of Queensland, St Lucia, QLD, Australia.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.
المصدر: Frontiers in microbiology [Front Microbiol] 2021 Feb 23; Vol. 12, pp. 628879. Date of Electronic Publication: 2021 Feb 23 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne : Frontiers Research Foundation
مستخلص: The BAM complex in Escherichia coli is composed of five proteins, BamA-E. BamA and BamD are essential for cell viability and are required for the assembly of β-barrel outer membrane proteins. Consequently, BamA and BamD are indispensable for secretion via the classical autotransporter pathway (Type 5a secretion). In contrast, BamB, BamC, and BamE are not required for the biogenesis of classical autotransporters. Recently, we demonstrated that TamA, a homologue of BamA, and its partner protein TamB, were required for efficient secretion of proteins via the classical autotransporter pathway. The trimeric autotransporters are a subset of the Type 5-secreted proteins. Unlike the classical autotransporters, they are composed of three identical polypeptide chains which must be assembled together to allow secretion of their cognate passenger domains. In contrast to the classical autotransporters, the role of the Bam and Tam complex components in the biogenesis of the trimeric autotransporters has not been investigated fully. Here, using the Salmonella enterica trimeric autotransporter SadA and the structurally similar YadA protein of Yersinia spp., we identify the importance of BamA and BamD in the biogenesis of the trimeric autotransporters and reveal that BamB, BamC, BamE, TamA and TamB are not required for secretion of functional passenger domain on the cell surface.
Importance: The secretion of trimeric autotransporters (TAA's) has yet to be fully understood. Here we show that efficient secretion of TAAs requires the BamA and D proteins, but does not require BamB, C or E. In contrast to classical autotransporter secretion, neither trimeric autotransporter tested required TamA or B proteins to be functionally secreted.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2021 Rooke, Icke, Wells, Rossiter, Browning, Morris, Leo, Schütz, Autenrieth, Cunningham, Linke and Henderson.)
References: Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20907-12. (PMID: 23213248)
Microbiology (Reading). 2009 Dec;155(Pt 12):3982-3991. (PMID: 19815580)
Nat Rev Microbiol. 2009 Mar;7(3):206-14. (PMID: 19182809)
FEMS Microbiol Lett. 2006 Nov;264(1):22-30. (PMID: 17020545)
Philos Trans R Soc Lond B Biol Sci. 2012 Apr 19;367(1592):1088-101. (PMID: 22411980)
Protein Eng Des Sel. 2008 Aug;21(8):475-84. (PMID: 18467342)
J Bacteriol. 1996 Mar;178(6):1770-3. (PMID: 8626309)
EMBO J. 2004 Feb 25;23(4):701-11. (PMID: 14765110)
Science. 2010 May 14;328(5980):890-2. (PMID: 20378773)
J Biol Chem. 2011 Dec 9;286(49):42283-42291. (PMID: 22006918)
Nat Methods. 2012 Dec;9(12):1212-7. (PMID: 23142870)
Int J Med Microbiol. 2015 Feb;305(2):276-82. (PMID: 25596886)
Protein Eng Des Sel. 2008 Jan;21(1):11-8. (PMID: 18093992)
Res Microbiol. 2004 Mar;155(2):53-60. (PMID: 14990256)
J Bacteriol. 2009 Nov;191(22):7074-85. (PMID: 19767435)
Mol Microbiol. 2019 Mar;111(3):844-862. (PMID: 30600549)
Genome Biol Evol. 2016 Jun 13;8(6):1690-705. (PMID: 27190006)
Trends Biochem Sci. 2006 Oct;31(10):563-71. (PMID: 16919958)
Trends Microbiol. 2005 May;13(5):199-205. (PMID: 15866036)
Microbiology (Reading). 2010 Aug;156(Pt 8):2459-2469. (PMID: 20447993)
Mol Microbiol. 2008 Jun;68(5):1216-27. (PMID: 18430136)
Microbiology (Reading). 2007 Jan;153(Pt 1):59-70. (PMID: 17185535)
PLoS One. 2010 Dec 22;5(12):e14403. (PMID: 21203509)
J Vis Exp. 2018 Sep 1;(139):. (PMID: 30222159)
J Infect Dis. 2001 Mar 1;183 Suppl 1:S28-31. (PMID: 11171009)
Mol Syst Biol. 2006;2:2006.0008. (PMID: 16738554)
Mol Microbiol. 2006 Jul;61(1):151-64. (PMID: 16824102)
PLoS One. 2013 Dec 23;8(12):e84512. (PMID: 24376817)
Mol Microbiol. 2005 Sep;57(5):1450-9. (PMID: 16102012)
Genes Dev. 2007 Oct 1;21(19):2473-84. (PMID: 17908933)
J Bacteriol. 2007 Dec;189(24):9011-9. (PMID: 17921300)
FEMS Microbiol Lett. 2007 Sep;274(2):163-72. (PMID: 17610513)
Mol Microbiol. 2008 Jan;67(1):188-201. (PMID: 18047580)
J Bacteriol. 2007 Jul;189(14):5393-8. (PMID: 17513479)
Cell. 2005 Apr 22;121(2):235-45. (PMID: 15851030)
Trends Microbiol. 2006 Jun;14(6):264-70. (PMID: 16678419)
Science. 2003 Jan 10;299(5604):262-5. (PMID: 12522254)
Mol Microbiol. 2010 Nov;78(4):932-46. (PMID: 20815824)
Gut Microbes. 2010 Sep;1(5):339-344. (PMID: 21327044)
Nat Rev Microbiol. 2012 Feb 16;10(3):213-25. (PMID: 22337167)
Nat Microbiol. 2016 May 16;1(7):16064. (PMID: 27572967)
J Struct Biol. 2006 Aug;155(2):154-61. (PMID: 16675268)
Infect Immun. 2011 Nov;79(11):4342-52. (PMID: 21859856)
J Bacteriol. 2012 Jan;194(2):317-24. (PMID: 22037403)
Biochim Biophys Acta. 2005 Jul 30;1713(2):92-112. (PMID: 15993836)
J Bacteriol. 2006 Oct;188(20):7186-94. (PMID: 17015657)
FEMS Microbiol Lett. 2004 Jan 15;230(1):73-83. (PMID: 14734168)
Environ Microbiol. 2008 Mar;10(3):589-604. (PMID: 18237301)
Trends Microbiol. 2000 Dec;8(12):529-32. (PMID: 11115743)
EMBO Rep. 2011 Feb;12(2):123-8. (PMID: 21212804)
mBio. 2019 Oct 22;10(5):. (PMID: 31641085)
J Bacteriol. 2011 Aug;193(16):4250-3. (PMID: 21665980)
Microbiol Mol Biol Rev. 2004 Dec;68(4):692-744. (PMID: 15590781)
Environ Microbiol. 2009 Jul;11(7):1803-14. (PMID: 19508554)
Nat Struct Mol Biol. 2012 Apr 01;19(5):506-10, S1. (PMID: 22466966)
Virulence. 2017 Oct 3;8(7):1170-1188. (PMID: 28118090)
J Immunol. 2012 Nov 15;189(10):4900-8. (PMID: 23071281)
Trends Microbiol. 2001 Dec;9(12):573-8. (PMID: 11728862)
Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6400-5. (PMID: 17404237)
فهرسة مساهمة: Keywords: Bam complex; autotransporter; outer membrane assembly; protein secretion; trimeric autotransporter adhesin
تواريخ الأحداث: Date Created: 20210312 Latest Revision: 20220421
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC7940764
DOI: 10.3389/fmicb.2021.628879
PMID: 33708185
قاعدة البيانات: MEDLINE
الوصف
تدمد:1664-302X
DOI:10.3389/fmicb.2021.628879