دورية أكاديمية
أعرض في EDS

Admission hyperglycemia and all-cause mortality in diabetic and non-diabetic patients with acute myocardial infarction: a tertiary center analysis.

التفاصيل البيبلوغرافية
العنوان: Admission hyperglycemia and all-cause mortality in diabetic and non-diabetic patients with acute myocardial infarction: a tertiary center analysis.
المؤلفون: Ferreira JA; Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal. joaoaferreira29@gmail.com., Baptista RM; Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.; Faculty of Medicine, iCBR, University of Coimbra, Coimbra, Portugal., Monteiro SR; Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal., Gonçalves FM; Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal., Monteiro PF; Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.; Faculty of Medicine, iCBR, University of Coimbra, Coimbra, Portugal., Gonçalves LM; Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Praceta, R. Professor Mota Pinto, 3004-561, Coimbra, Portugal.; Faculty of Medicine, iCBR, University of Coimbra, Coimbra, Portugal.
المصدر: Internal and emergency medicine [Intern Emerg Med] 2021 Nov; Vol. 16 (8), pp. 2109-2119. Date of Electronic Publication: 2021 Mar 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Italy NLM ID: 101263418 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1970-9366 (Electronic) Linking ISSN: 18280447 NLM ISO Abbreviation: Intern Emerg Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Milan : Springer
Original Publication: Rome, Italy : CEPI-AIM Group, 2006-
مواضيع طبية MeSH: Hyperglycemia/*blood , Myocardial Infarction/*mortality , Patient Admission/*statistics & numerical data, Aged ; Aged, 80 and over ; Blood Glucose/analysis ; Female ; Hospital Mortality/trends ; Humans ; Hyperglycemia/complications ; Hyperglycemia/epidemiology ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Tertiary Care Centers/organization & administration ; Tertiary Care Centers/statistics & numerical data ; Time Factors
مستخلص: Admission hyperglycemia (AH) is associated with worse prognosis in patients with acute myocardial infarction (AMI). Controversy remains whether the impact of AH differs among patients previously diagnosed with diabetes mellitus (DM). We retrospectively evaluated consecutive patients admitted in a coronary care unit with AMI, from 2006 to 2014. Patients were divided into 4 groups: patients without known DM with admission glycemia (AG) ≤ 143 mg/dL (group 1), patients without known DM with AG > 143 mg/dL (group 2), known DM with AG ≤ 213 mg/dL (group 3), and known DM with AG > 213 mg/dL (group 4). Primary outcome was defined as all-cause mortality during follow-up. A total of 2768 patients were included: 1425 in group 1, 426 in group 2, 593 in group 3, and 325 in group 4. After a median follow-up of 5.6 years, 1047 (37.8%) patients reached primary outcome. After multivariate analysis, group 4 was associated with the worst prognosis (HR 3.103, p < 0.001) followed by group 3 (HR 1.639, p = 0.002) and group 2 (HR 1.557, p = 0.039), when compared to group 1. When groups were stratified by type of AMI, patients in group 2 had a worse prognosis than patients in group 3 in the case of non-ST-segment elevation AMI. AH is associated with higher all-cause mortality in patients with AMI, irrespective of previous diabetic status.
(© 2021. Società Italiana di Medicina Interna (SIMI).)
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فهرسة مساهمة: Keywords: Acute myocardial infarction; Admission hyperglycemia; Diabetes mellitus; Prognosis
المشرفين على المادة: 0 (Blood Glucose)
تواريخ الأحداث: Date Created: 20210313 Date Completed: 20211129 Latest Revision: 20211129
رمز التحديث: 20231215
DOI: 10.1007/s11739-021-02693-0
PMID: 33713285
قاعدة البيانات: MEDLINE
الوصف
تدمد:1970-9366
DOI:10.1007/s11739-021-02693-0