دورية أكاديمية

Influence of Doxycycline and InGaAlP Diode Laser at 660 nm Wavelength in the Treatment of Periodontitis Induced in Rats: In Vivo Study.

التفاصيل البيبلوغرافية
العنوان: Influence of Doxycycline and InGaAlP Diode Laser at 660 nm Wavelength in the Treatment of Periodontitis Induced in Rats: In Vivo Study.
المؤلفون: Silveira GRC; Faculty of Dentistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil., de Lima DC; Faculty of Dentistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil., Cintra LTÂ; Faculty of Dentistry, Department of Restorative Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil., Brigagão MRPL; Faculty of Dentistry, Department of Biochemistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil., Ervolino E; Faculty of Dentistry, Department of Basic Sciences, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil., Fernandes LA; Faculty of Dentistry, Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
المصدر: Photochemistry and photobiology [Photochem Photobiol] 2021 Sep; Vol. 97 (5), pp. 1104-1115. Date of Electronic Publication: 2021 Mar 25.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: American Society for Photobiology Country of Publication: United States NLM ID: 0376425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-1097 (Electronic) Linking ISSN: 00318655 NLM ISO Abbreviation: Photochem Photobiol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2004->: Lawrence KS : American Society for Photobiology
Original Publication: Augusta, GA: American Society for Photobiology, <1996->
مواضيع طبية MeSH: Lasers, Semiconductor*/therapeutic use , Periodontitis*/drug therapy, Animals ; Combined Modality Therapy ; Doxycycline/pharmacology ; Doxycycline/therapeutic use ; Rats ; Rats, Wistar ; Root Planing
مستخلص: This study evaluated the influence of Doxycycline (DOX) and Low-Intensity Laser (LIL) (InGaAlP diode laser) as scaling and root planing (SRP) adjuvants in the treatment of periodontitis induced in rats. The rats received periodontal disease induction, and after 7 days, the ligature was removed, and the animals were divided into groups/treatments: NT-receive no treatment; SRP-submitted only to SRP; DOX-submitted to SRP and DOX irrigation; LIL-submitted to SRP and LIL irradiation; and DOX + LIL-submitted to SRP treatments, DOX irrigation and LIL irradiation. The animals were sacrificed at 7, 15 and 30 days, and then, the analyses were performed. A lower concentration of Alpha-glycoprotein acid and Complement 3 was observed in the DOX + LIL group compared to all the other groups in all the periods, and for Complement 4 at 15 and 30 days (P < 0.01). A lower bone loss (BL) was observed in the DOX + LIL group compared to all the other groups in all the periods (P < 0.01). It can be concluded that LIL was effective in the reduction of proteins, and its association with DOX was effective in the reduction of proteins and BL, in the treatment of periodontal induction in rats.
(© 2021 American Society for Photobiology.)
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المشرفين على المادة: N12000U13O (Doxycycline)
تواريخ الأحداث: Date Created: 20210313 Date Completed: 20220406 Latest Revision: 20220406
رمز التحديث: 20221213
DOI: 10.1111/php.13414
PMID: 33713346
قاعدة البيانات: MEDLINE
الوصف
تدمد:1751-1097
DOI:10.1111/php.13414