دورية أكاديمية

Medication regimen complexity of coronary artery disease patients.

التفاصيل البيبلوغرافية
العنوان: Medication regimen complexity of coronary artery disease patients.
المؤلفون: Tinoco MS; Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Groia-Veloso RCS; Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Santos JNDD; Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Cruzeiro MGM; Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Dias BM; Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Reis AMM; Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
المصدر: Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2021 Mar 15; Vol. 19, pp. eAO5565. Date of Electronic Publication: 2021 Mar 15 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English; Portuguese
بيانات الدورية: Publisher: Instituto de Ensino e Pesquisa Albert Einstein Country of Publication: Brazil NLM ID: 101281800 Publication Model: eCollection Cited Medium: Internet ISSN: 2317-6385 (Electronic) Linking ISSN: 16794508 NLM ISO Abbreviation: Einstein (Sao Paulo) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: São Paulo, SP : Instituto de Ensino e Pesquisa Albert Einstein
مواضيع طبية MeSH: Coronary Artery Disease*/drug therapy , Medication Adherence* , Polypharmacy*, Comorbidity ; Cross-Sectional Studies ; Diabetes Mellitus ; Humans ; Hypertension ; Logistic Models
مستخلص: Objective: To determine the factors associated with the high complexity of medication regimen in patients with coronary artery disease.
Methods: A cross-sectional study was carried out in a multiprofessional cardiology outpatient clinic, in the Secondary Care of the Unified Health System, where sociodemographic (age, sex, and education), clinical (number of health conditions, cardiovascular diagnoses, and comorbidities) and pharmacotherapeutic (adherence, polypharmacy, and cardiovascular polypharmacy) characteristics were collected. These were related to complexity of medication regimen, measured through the medication regimen complexity index. The classification of high complexity of medication regimen was carried out using standardization for the older adults and stratification for adult patients, as suggested in the literature.
Results: The total complexity medication regimen of 148 patients had a median of 17.0 (interquartile range of 10.5). In the univariate analysis, the factors associated with high complexity were heart failure, diabetes mellitus, hypertension, five or more diseases, and non-adherence to treatment. In the final model, after logistic regression, there was a statistically significant association (p<0.05) with the variables diabetes mellitus, hypertension, and non-adherence.
Conclusion: The high complexity of medication regimen in patients with coronary artery disease was associated with the presence of diabetes mellitus, hypertension, and reports of non-adherence to treatment.
References: Glob Heart. 2019 Sep;14(3):303-310. (PMID: 31451238)
J Am Pharm Assoc (Wash). 2000 Jul-Aug;40(4):475-85. (PMID: 10932456)
Geriatr Gerontol Int. 2018 Jun;18(6):853-859. (PMID: 29380500)
Clin Ther. 2013 Apr;35(4):385-398.e1. (PMID: 23541707)
J Appl Gerontol. 2019 Jun;38(6):866-883. (PMID: 28645225)
Int J Cardiol. 2016 Feb 15;205:147-156. (PMID: 26736090)
Diabetes Care. 2004 May;27(5):1218-24. (PMID: 15111553)
Cad Saude Publica. 2003 May-Jun;19(3):717-24. (PMID: 12806474)
BMJ Open Diabetes Res Care. 2019 Jun 28;7(1):e000685. (PMID: 31321061)
Ann Pharmacother. 2016 Nov;50(11):926-934. (PMID: 27371949)
Circulation. 2016 Jan 26;133(4):422-33. (PMID: 26811272)
Eur J Clin Pharmacol. 2017 Nov;73(11):1475-1489. (PMID: 28779460)
Ann Pharmacother. 2004 Sep;38(9):1369-76. (PMID: 15266038)
J Gen Intern Med. 2001 Feb;16(2):77-82. (PMID: 11251757)
Pharm Pract (Granada). 2015 Oct-Dec;13(4):659. (PMID: 26759621)
J Am Geriatr Soc. 2017 Apr;65(4):747-753. (PMID: 27991653)
J Clin Pharm Ther. 2012 Dec;37(6):637-42. (PMID: 22607618)
Int J Pharm Pract. 2020 Aug;28(4):337-345. (PMID: 31886591)
Int J Clin Pharm. 2014 Aug;36(4):750-6. (PMID: 24906719)
Am J Med. 2017 Sep;130(9):1092-1098.e2. (PMID: 28454906)
Int J Clin Pharm. 2013 Apr;35(2):217-24. (PMID: 23212732)
Br J Clin Pharmacol. 2014 Jun;77(6):1073-82. (PMID: 24428591)
Ann Pharmacother. 2016 Feb;50(2):89-95. (PMID: 26681444)
SAGE Open Med. 2016 Feb 19;4:2050312116632426. (PMID: 26985392)
Pharmacotherapy. 2014 Aug;34(8):826-35. (PMID: 24947636)
Arq Bras Cardiol. 2007 Oct;89(4):210-8. (PMID: 17992376)
تواريخ الأحداث: Date Created: 20210317 Date Completed: 20210319 Latest Revision: 20210320
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC7935084
DOI: 10.31744/einstein_journal/2021AO5565
PMID: 33729285
قاعدة البيانات: MEDLINE
الوصف
تدمد:2317-6385
DOI:10.31744/einstein_journal/2021AO5565