دورية أكاديمية
Case of hypoactive delirium precipitated by thiamine deficiency.
| العنوان: | Case of hypoactive delirium precipitated by thiamine deficiency. |
|---|---|
| المؤلفون: | Truong T; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Hetzel F; MetroHealth Medical Center, Department of Internal Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Stiff KM; Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA., Husnain MG; MetroHealth Medical Center, Hospital Medicnie, Case Western Reserve University, Cleveland, Ohio, USA husnainmg82@gmail.com. |
| المصدر: | BMJ case reports [BMJ Case Rep] 2021 Mar 17; Vol. 14 (3). Date of Electronic Publication: 2021 Mar 17. |
| نوع المنشور: | Journal Article; Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group |
| مواضيع طبية MeSH: | Beriberi* , Delirium*/diagnosis , Delirium*/etiology , Thiamine Deficiency*/complications , Thiamine Deficiency*/diagnosis , Thiamine Deficiency*/drug therapy , Wernicke Encephalopathy*/diagnosis , Wernicke Encephalopathy*/drug therapy , Wernicke Encephalopathy*/etiology, Humans ; Male ; Middle Aged ; Thiamine/therapeutic use |
| مستخلص: | Thiamine is an essential cofactor in the process of nucleic acid synthesis. Neuronal tissues are especially sensitive to thiamine deficiency, manifesting as Wernicke's encephalopathy (WE). The typical triad of WE, encephalopathy, oculomotor dysfunction and gait ataxia, is only present in less than one-third of the cases. We present the case of a middle-aged man with hypoactive delirium due to presumed thiamine deficiency, who had a prolonged hospital course and a delayed diagnosis of the cause of altered mental status. The presentation of this disorder solely as a decreased level of consciousness is uncommon but has been reported in the literature. It is essential to recognise WE as a treatable condition that may manifest only as a hypoactive delirium. The delay in the diagnosis and treatment may lead to coma and death. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.) |
| References: | J Neurol Neurosurg Psychiatry. 1986 Apr;49(4):341-5. (PMID: 3701343) Innov Clin Neurosci. 2013 Apr;10(4):26-32. (PMID: 23696956) AJNR Am J Neuroradiol. 2008 Jan;29(1):164-9. (PMID: 18192344) Eur J Neurol. 2010 Dec;17(12):1408-18. (PMID: 20642790) Lancet. 1978 Aug 19;2(8086):400-1. (PMID: 79763) Prog Cardiovasc Dis. 2018 May - Jun;61(1):27-32. (PMID: 29360523) JPEN J Parenter Enteral Nutr. 2015 Jul;39(5):503-20. (PMID: 25564426) Cochrane Database Syst Rev. 2013 Jul 01;(7):CD004033. (PMID: 23818100) Cureus. 2018 Aug 22;10(8):e3187. (PMID: 30364782) Psychosomatics. 2016 Jan-Feb;57(1):71-81. (PMID: 26791514) Prim Care Companion CNS Disord. 2015 May 21;17(3):. (PMID: 26644959) Med J Aust. 2011 May 2;194(9):483-4. (PMID: 21534910) Support Care Cancer. 2015 Aug;23(8):2427-33. (PMID: 25617070) Crit Care Med. 2018 Dec;46(12):2029-2035. (PMID: 30234569) Alcohol Alcohol. 2008 Mar-Apr;43(2):174-9. (PMID: 18056751) BMJ. 2017 May 25;357:j2047. (PMID: 28546253) Intern Med J. 2014 Sep;44(9):911-5. (PMID: 25201422) |
| فهرسة مساهمة: | Keywords: delirium; vitamins and supplements |
| المشرفين على المادة: | X66NSO3N35 (Thiamine) |
| تواريخ الأحداث: | Date Created: 20210318 Date Completed: 20210514 Latest Revision: 20231031 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC7978061 |
| DOI: | 10.1136/bcr-2020-239886 |
| PMID: | 33731408 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1757-790X |
|---|---|
| DOI: | 10.1136/bcr-2020-239886 |