تقرير
Oral amelanotic malignant melanoma: a case report.
| العنوان: | Oral amelanotic malignant melanoma: a case report. |
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| المؤلفون: | Aziz Z; Maxillofacial Surgery Department, University Hospital Center Mohammed VI, Marrakesh, Morocco., Aboulouidad S; Maxillofacial Surgery Department, University Hospital Center Mohammed VI, Marrakesh, Morocco., Bouihi ME; Maxillofacial Surgery Department, University Hospital Center Mohammed VI, Marrakesh, Morocco., Hattab NM; Maxillofacial Surgery Department, University Hospital Center Mohammed VI, Marrakesh, Morocco., Chehbouni M; Department of Otorhinolaryngology, University Hospital Center Mohammed VI, Marrakesh, Morocco., Raji A; Department of Otorhinolaryngology, University Hospital Center Mohammed VI, Marrakesh, Morocco. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2020 Dec 16; Vol. 37, pp. 350. Date of Electronic Publication: 2020 Dec 16 (Print Publication: 2020). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Maxillary Neoplasms/*diagnosis , Melanoma, Amelanotic/*diagnosis, Adult ; Biopsy ; Female ; Humans ; Immunohistochemistry ; Maxillary Neoplasms/pathology ; Maxillary Neoplasms/surgery ; Melanoma, Amelanotic/pathology ; Melanoma, Amelanotic/surgery ; Prognosis |
| مستخلص: | Amelanotic malignant melanoma is an extremely rare and aggressive oral tumor. Herein we report the case of a 42-year-old woman presented with a painful growth in anterior maxillary region. Intra-oral examination showed a non-pigmented exophytic mass occupying the anterior maxillary sector. Incisional biopsy with immunohistochemistry examination revealed a malignant melanoma as it strongly expressed melan A and S-100. Facial computed tomography showed extension to the maxillary bone and hard palate. After thoraco-abdominal computed tomography revealing absence of metastasis, tumor resection was performed respecting 2cm security margin. Oral localization of malignant melanoma is rare especially its amelanotic variant. Lack of pigmentation makes the diagnosis more difficult, usually resulting in treatment delay and making the prognosis even worse. Early detection by histological and immunochemistry examination combined to wide resection are the keys to improving the survival for patients with oral amelanotic melanoma. Competing Interests: The authors declare no competing interests. (Copyright: Zakaria Aziz et al.) |
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| فهرسة مساهمة: | Keywords: Malignant melanoma; amelanotic; case report; maxillary gingiva; oral cavity |
| تواريخ الأحداث: | Date Created: 20210319 Date Completed: 20210406 Latest Revision: 20210406 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC7934186 |
| DOI: | 10.11604/pamj.2020.37.350.27330 |
| PMID: | 33738038 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2020.37.350.27330 |