دورية أكاديمية

An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta.

التفاصيل البيبلوغرافية
العنوان: An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta.
المؤلفون: Chung CY; Department of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo 315100, PR China., Yang J; School of Mathematical Sciences, University of Nottingham Ningbo China, Ningbo 315100, PR China. Electronic address: Jie.Yang@hull.ac.uk., He J; Department of Chemical and Environmental Engineering, University of Nottingham Ningbo China, Ningbo 315100, PR China., Yang X; Department of Mechanical, Materials and Manufacturing Engineering, University of Nottingham Ningbo China, Ningbo 315100, PR China., Hubbard R; School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK., Ji D; State key laboratory of Atmospheric Boundary Layer Physics and Chemistry, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100191, PR China.
المصدر: The Science of the total environment [Sci Total Environ] 2021 Jul 20; Vol. 779, pp. 146427. Date of Electronic Publication: 2021 Mar 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1026 (Electronic) Linking ISSN: 00489697 NLM ISO Abbreviation: Sci Total Environ Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam, Elsevier.
مواضيع طبية MeSH: Air Pollutants*/adverse effects , Air Pollutants*/analysis , Air Pollution*/adverse effects , Air Pollution*/analysis , Lung Neoplasms*, China/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Particulate Matter/adverse effects ; Particulate Matter/analysis ; Rivers
مستخلص: Lung cancer (LC) mortality, as one of the top cancer deaths in China, has been associated with increased levels of exposure to ambient air pollutants. In this study, different lag times on weekly basis were applied to study the association of air pollutants (PM2.5, PM10, and NO2) and LC mortality in Ningbo, and in subpopulations at different age groups and genders. Furthermore, seasonal variations of pollutant concentrations and meteorological variables (temperature, relative humidity, and wind speed) were analysed. A generalised additive model (GAM) using Poisson regression was employed to estimate the effect of single pollutant model on LC mortality in Yangtze River Delta using Ningbo as a case study. It was reported that there were statistically significant relationships between lung cancer mortality and air pollutants. Increases of 6.2% (95% confidence interval [CI]: 0.2% to 12.6%) and 4.3% (95% CI: 0.1% to 8.5%) weekly total LC mortality with a 3-week lag time were linked to each 10 μg/m 3 increase of weekly average PM 2.5 and PM 10 respectively. The association of air pollutants (PM 2.5 , PM 10 and NO 2 ) and LC mortality with a 3-week lag time was also found statistically significant during periods of low temperature (T < 18 °C), low relative humidity (H < 73.7%) and low wind speed (u < 2.8 m/s), respectively. The female population was found to be more susceptible to the exposure to air pollution than the male population. In addition, the population with an age of 50 years or above was shown to be more sensitive to ambient air pollutant. These outcomes indicated that increased risk of lung cancer mortality was evidently linked to exposure to ambient air pollutant on a weekly basis. The impact of weekly variation on the LC mortality and air pollutant levels should be considered in air pollution-related health burden analysis.
Competing Interests: Declaration of competing interest I would like to state on behalf of all the authors that there is no conflict of interest among all the co-authors for the submitted manuscript entitled “An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta” for publication in Science of the Total Environment.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Ambient air pollution; Lag time; Lung cancer mortality; Meteorological factors; Modelling; Yangtze River Delta
المشرفين على المادة: 0 (Air Pollutants)
0 (Particulate Matter)
تواريخ الأحداث: Date Created: 20210322 Date Completed: 20210521 Latest Revision: 20210521
رمز التحديث: 20221213
DOI: 10.1016/j.scitotenv.2021.146427
PMID: 33752019
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1026
DOI:10.1016/j.scitotenv.2021.146427