دورية أكاديمية
The Versatile Wayfinder: Prefrontal Contributions to Spatial Navigation.
| العنوان: | The Versatile Wayfinder: Prefrontal Contributions to Spatial Navigation. |
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| المؤلفون: | Patai EZ; Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, UK; Institute of Behavioural Neuroscience, Department of Experimental Psychology, Division of Psychology and Language sciences, University College London, UK. Electronic address: e.patai@ucl.ac.uk., Spiers HJ; Institute of Behavioural Neuroscience, Department of Experimental Psychology, Division of Psychology and Language sciences, University College London, UK. Electronic address: h.spiers@ucl.ac.uk. |
| المصدر: | Trends in cognitive sciences [Trends Cogn Sci] 2021 Jun; Vol. 25 (6), pp. 520-533. Date of Electronic Publication: 2021 Mar 19. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 9708669 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-307X (Electronic) Linking ISSN: 13646613 NLM ISO Abbreviation: Trends Cogn Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kidlington, Oxford, UK : Elsevier Science, c1997- |
| مواضيع طبية MeSH: | Spatial Navigation*, Gyrus Cinguli ; Hippocampus ; Prefrontal Cortex |
| مستخلص: | The prefrontal cortex (PFC) supports decision-making, goal tracking, and planning. Spatial navigation is a behavior that taxes these cognitive processes, yet the role of the PFC in models of navigation has been largely overlooked. In humans, activity in dorsolateral PFC (dlPFC) and ventrolateral PFC (vlPFC) during detours, reveal a role in inhibition and replanning. Dorsal anterior cingulate cortex (dACC) is implicated in planning and spontaneous internally-generated changes of route. Orbitofrontal cortex (OFC) integrates representations of the environment with the value of actions, providing a 'map' of possible decisions. In rodents, medial frontal areas interact with hippocampus during spatial decisions and switching between navigation strategies. In reviewing these advances, we provide a framework for how different prefrontal regions may contribute to different stages of navigation. Competing Interests: Declaration of Interests The authors have no interests to declare. (Copyright © 2021 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: decision-making; hippocampus; navigation; planning; prefrontal cortex |
| تواريخ الأحداث: | Date Created: 20210323 Date Completed: 20210527 Latest Revision: 20210527 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.tics.2021.02.010 |
| PMID: | 33752958 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1879-307X |
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| DOI: | 10.1016/j.tics.2021.02.010 |