دورية أكاديمية
أعرض في EDS

Impacts of the COVID-19 Pandemic on the Mental Health and Motor Deficits in Cuban Patients with Cerebellar Ataxias.

التفاصيل البيبلوغرافية
العنوان: Impacts of the COVID-19 Pandemic on the Mental Health and Motor Deficits in Cuban Patients with Cerebellar Ataxias.
المؤلفون: González-Garcés Y; Centre for the Research and Rehabilitation of Hereditary Ataxias, Libertad 26, Holguín, Cuba., Domínguez-Barrios Y; National Institute of Neurology and Neurosurgery 'Rafael Estrada', 29th Street 139, Vedado, Plaza de la Revolución, Havana, Cuba., Zayas-Hernández A; Polyclinic 'Manuel Fajardo Rivero', Urbano Noris, Holguín, Cuba., Sigler-Villanueva AA; University Hospital 'Antonio Luaces', 'Máximo Gomez' 257, Ciego de Avila, Cuba., Canales-Ochoa N; Centre for the Research and Rehabilitation of Hereditary Ataxias, Libertad 26, Holguín, Cuba., Hernández Oliver MO; Pediatric Hospital 'José Luis Miranda', '26 de Julio' Ave, Escambray, Santa Clara, Cuba., Ramírez-Bautista MB; University Hospital 'Lucía Iñíguez', 'Celia Sánchez' Avenue 1, Holguín, Cuba., Caballero-Laguna A; Clinical & Surgical Hospital 'Guillermo Domínguez' Puerto Padre, Las Tunas, Cuba., Arrufat-Pie E; Clinical & Surgical Hospital 'Manuel Piti Fajardo', Plaza de la Revolución, Cuba., Carrillo-Rodes FJ; Centre for the Research and Rehabilitation of Hereditary Ataxias, Libertad 26, Holguín, Cuba., Medrano-Montero J; Centre for the Research and Rehabilitation of Hereditary Ataxias, Libertad 26, Holguín, Cuba., Rodríguez-Álvarez Y; University of Camagüey, Camagüey, Cuba., Gámez-Rodríguez O; University Hospital 'Juan Bruno Zayas', Carretera del Caney Street. Pastorita, Santiago de Cuba, Cuba., Guerra-Rondón LA; Municipal Center of Medical Genetics, 1st Street, Cauto Cristo, Granma, Cuba., Aguilera-Batista O; Medical University of Holguin, Holguin, Cuba., Vazquez-Mojena Y; Cuban Centre for Neuroscience, Playa. 190 St. And 25th Ave., 19818, Playa, Havana, Cuba., Rodríguez-Labrada R; Cuban Centre for Neuroscience, Playa. 190 St. And 25th Ave., 19818, Playa, Havana, Cuba. roberto.rodriguez@cneuro.edu.cu., Velázquez-Pérez L; Cuban Academy of Sciences, Cuba St. 460, between Teniente Rey St. and Compostela St. Habana Vieja, 19100, Havana, Cuba. velazq63@gmail.com.
مؤلفون مشاركون: Cuban Hereditary Ataxias Network
المصدر: Cerebellum (London, England) [Cerebellum] 2021 Dec; Vol. 20 (6), pp. 896-903. Date of Electronic Publication: 2021 Mar 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101089443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4230 (Electronic) Linking ISSN: 14734222 NLM ISO Abbreviation: Cerebellum Subsets: MEDLINE
أسماء مطبوعة: Publication: <2006->: New York : Springer
Original Publication: London : Martin Dunitz, c2002-
مواضيع طبية MeSH: Mental Health*, COVID-19/*diagnosis , COVID-19/*psychology , Cerebellar Ataxia/*complications , SARS-CoV-2/*isolation & purification, Adult ; Aged ; Anxiety/epidemiology ; COVID-19/epidemiology ; COVID-19 Nucleic Acid Testing ; Case-Control Studies ; Cerebellar Ataxia/epidemiology ; Cerebellar Ataxia/psychology ; Cuba/epidemiology ; Depression/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; RNA, Viral ; SARS-CoV-2/genetics
مستخلص: Although there are no convincing evidences of detrimental effect of SARS-CoV2 infection on the cerebellum, the COVID-19 pandemic could impact the life quality of patients with cerebellar ataxias, but few studies have addressed this concern. To assess the motor and mental health changes caused by the COVID-19 pandemics in Cuban patients with cerebellar ataxias, three hundred four patients with cerebellar ataxias and 167 healthy controls were interviewed for risks of exposure to COVID-19, and the self-perception of the pandemics' impact on the disease progression and on the mental health. All subjects underwent the Hospital Anxiety and Depression Scale. The patients reported low exposition to SARS-CoV2 infection, but one case was confirmed with a mild COVID-19. Overall, depressive and anxiety symptoms were significantly and marginally increased in patients, respectively, with higher scores in cases with severe and moderate ataxia. Positive patient's impression of psychopathological changes was associated to increased age, age at onset, and anxiety. Sixty-seven patients had a positive self-perception of ataxia progression, which was mainly influenced by higher anxiety scores but not by the adherence to at-home exercise programs. However, the practice of physical exercise was related with lower depression and anxiety scores, but this therapeutical effect was not significantly influenced by the disease stage. We demonstrated the negative effect of the COVID-19 pandemic on the mental and motor deficits in Cuban patients with cerebellar ataxias and the positive effect of the at-home physical exercise programs on their mental well-being. These findings give rationales to develop tele-medicine approaches to minimize these health impacts and to study the long-term effects of such sequelae and accordingly define their treatments.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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فهرسة مساهمة: Keywords: COVID-19; Cerebellar ataxias; Mental health; Pandemic; SARS-CoV2
المشرفين على المادة: 0 (RNA, Viral)
تواريخ الأحداث: Date Created: 20210326 Date Completed: 20211220 Latest Revision: 20220218
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7993441
DOI: 10.1007/s12311-021-01260-9
PMID: 33768478
قاعدة البيانات: MEDLINE
الوصف
تدمد:1473-4230
DOI:10.1007/s12311-021-01260-9