دورية أكاديمية
أعرض في EDS

Predictors of controlled prescription drug non-medical and lifetime use among patients accessing public mental health services in Uganda: a cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: Predictors of controlled prescription drug non-medical and lifetime use among patients accessing public mental health services in Uganda: a cross-sectional study.
المؤلفون: Kamba PF; Department of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda kambaf2000@yahoo.com., Mulangwa J; Department of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda., Kageni P; Department of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda., Balikuna S; Department of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda., Kengo A; Department of Pharmacology, Faculty of Medicine, Gulu University, Gulu, Uganda., Mutamba BB; Department of Psychiatry, Butabika National Referral Mental Hospital, Kampala, Uganda., Sewankambo N; Department of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda., Adome RO; Department of Pharmacy, College of Health Sciences, Makerere University, Kampala, Uganda., Byakika-Kibwika P; Department of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
المصدر: BMJ open [BMJ Open] 2021 Mar 26; Vol. 11 (3), pp. e037602. Date of Electronic Publication: 2021 Mar 26.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BMJ Publishing Group Ltd, 2011-
مواضيع طبية MeSH: Illicit Drugs* , Mental Health Services* , Prescription Drugs* , Substance-Related Disorders*/epidemiology, Cross-Sectional Studies ; Humans ; Uganda/epidemiology
مستخلص: Objectives: We determined the prevalence of controlled prescription drug (CPD) non-medical and lifetime use and their predictors among patients at three public psychiatric clinics in Uganda to identify missed care opportunities, enhanced screening priorities, and drug control needs.
Methods: A cross-sectional survey of 1275 patients was performed from November to December 2018. Interviewer-administered semi-structured questionnaires, desk review guide and urine drug assays were employed. Questionnaire recorded CPD non-medical and illicit drug use history from patients' files, CPD lifetime use and risk factors. Desk review guide recorded recently prescribed drugs in patients' files to corroborate with urine assays. Predictors were analysed by multivariate logistic regression.
Results: From desk review, 145 (11.4%) patients had history of CPD non-medical use and 36 (2.8%) had used illicit drugs. Of 988 patients who provided urine, 166 (16.8%) self-medicated CPDs, particularly benzodiazepines while 12 (1.2%) used illicit drugs. Of those with drug-positive urine, 123 (69.1%) had no documented history of CPD non-medical and illicit drug use. Being an inpatient (OR=10.90, p<0.001) was independently associated with CPD non-medical use. Additionally, being an inpatient (OR=8.29, p<0.001) and tobacco consumption (OR=1.85, p=0.041) were associated with CPD non-medical and illicit drug use combined. Among participants, 119 (9.3%) reported CPD lifetime use, and this was independently associated with education level (OR=2.71, p<0.001) and history of treatment for substance abuse (OR=2.08, p=0.018).
Conclusions: CPD non-medical use is common among Uganda's psychiatric patients, and more prevalent than illicit drug use. Rapid diagnostic assays may be needed in psychiatric care in resource limited settings. It is necessary to assess how CPD non-medical use impacts mental care outcomes and patient safety. High risk groups like inpatients and tobacco consumers should be prioritised in psychiatric screening.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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معلومات مُعتمدة: D43 TW010132 United States TW FIC NIH HHS
فهرسة مساهمة: Keywords: clinical pharmacology; clinical physiology; forensic medicine; mental health; psychiatry; substance misuse
سلسلة جزيئية: Dryad 10.5061/dryad.ns1rn8ppb
المشرفين على المادة: 0 (Illicit Drugs)
0 (Prescription Drugs)
تواريخ الأحداث: Date Created: 20210327 Date Completed: 20210519 Latest Revision: 20210707
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8006833
DOI: 10.1136/bmjopen-2020-037602
PMID: 33771822
قاعدة البيانات: MEDLINE
الوصف
تدمد:2044-6055
DOI:10.1136/bmjopen-2020-037602