دورية أكاديمية
Anatomic location of residual disease after initial cholecystectomy independently determines outcomes after re-resection for incidental gallbladder cancer.
العنوان: | Anatomic location of residual disease after initial cholecystectomy independently determines outcomes after re-resection for incidental gallbladder cancer. |
---|---|
المؤلفون: | Ando T; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Sakata J; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan. jsakata2@med.niigata-u.ac.jp., Nomura T; Department of Gastrointestinal Surgery, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Chuo-ku, Niigata City, Niigata, 951-8566, Japan., Takano K; Department of Gastrointestinal Surgery, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Chuo-ku, Niigata City, Niigata, 951-8566, Japan., Takizawa K; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Miura K; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Hirose Y; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Kobayashi T; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Ichikawa H; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Hanyu T; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Shimada Y; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Nagahashi M; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan., Kosugi SI; Department of Digestive and General Surgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, 4132 Urasa, Minami-Uonuma, Niigata, 949-7302, Japan., Wakai T; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata City, Niigata, 951-8510, Japan. |
المصدر: | Langenbeck's archives of surgery [Langenbecks Arch Surg] 2021 Aug; Vol. 406 (5), pp. 1521-1532. Date of Electronic Publication: 2021 Apr 10. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9808285 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-2451 (Electronic) Linking ISSN: 14352443 NLM ISO Abbreviation: Langenbecks Arch Surg Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Berlin : Springer-Verlag, c1998- |
مواضيع طبية MeSH: | Gallbladder Neoplasms*/pathology , Gallbladder Neoplasms*/surgery, Cholecystectomy ; Humans ; Incidental Findings ; Neoplasm Staging ; Neoplasm, Residual/surgery ; Retrospective Studies |
مستخلص: | Purpose: This study aimed to elucidate the impact of anatomic location of residual disease (RD) after initial cholecystectomy on survival following re-resection of incidental gallbladder cancer (IGBC). Methods: Patients with pT2 or pT3 gallbladder cancer (36 with IGBC and 171 with non-IGBC) who underwent resection were analyzed. Patients with IGBC were classified as follows according to the anatomic location of RD after initial cholecystectomy: no RD (group 1); RD in the gallbladder bed, stump of the cystic duct, and/or regional lymph nodes (group 2); and RD in the extrahepatic bile duct and/or distant sites (group 3). Results: Timing of resection (IGBC vs. non-IGBC) did not affect survival in either multivariate or propensity score matching analysis. RD was found in 16 (44.4%) of the 36 patients with IGBC; R0 resection following re-resection was achieved in 32 patients (88.9%). Overall survival (OS) following re-resection was worse in group 3 (n = 7; 5-year OS, 14.3%) than in group 2 (n = 9; 5-year OS, 55.6%) (p = 0.035) or in group 1 (n = 20; 5-year OS, 88.7%) (p < 0.001). There was no survival difference between groups 1 and 2 (p = 0.256). Anatomic location of RD was independently associated with OS (group 2, HR 2.425, p = 0.223; group 3, HR 9.627, p = 0.024). Conclusion: The anatomic location of RD independently predicts survival following re-resection, which is effective for locoregional disease control in IGBC, similar to resection for non-IGBC. Not all patients with RD have poor survival following re-resection for IGBC. (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.) |
References: | Shirai Y, Yoshida K, Tsukada K, Muto T (1992) Inapparent carcinoma of the gallbladder: an appraisal of a radical second operation after simple cholecystectomy. Ann Surg 215:326–331. Søreide K, Guest RV, Harrison EM , Kendall TJ, Garden OJ, Wigmore SJ (2019) Systemic review of management of incidental gallbladder cancer after cholecystectomy. Br J Surg 106:32–45. Ethun CG, Le N, Lopez-Aguiar AG, Pawlik TM, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Krasnick BA, Weber SM, Salem A, Martin RCG, Scoggins CR, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Russell MC, Maithel SK (2017) Pathologic and prognostic implications of incidental versus nonincidental gallbladder cancer: a 10-institution study from the United States Extrahepatic Biliary Malignancy Consortium. Am Surg 83:679–686. Cherkassky L, D’Angelica M (2019) Gallbladder cancer: managing the incidental diagnosis. Surg Oncol Clin N Am 28:619–630. (PMID: 10.1016/j.soc.2019.06.005) Aloia TA, Járufe N, Javle M, Maithel SK, Roa JC, Adsay V, Coimbra FJF, Jarnagin WR (2015) Gallbladder: expert consensus statement. HPB 17:681–690. (PMID: 10.1111/hpb.12444) Wakai T, Shirai Y, Hatakeyama K (2002) Radical second resection provides survival benefit for patients with T2 gallbladder carcinoma first discovered after laparoscopic cholecystectomy. World J Surg 26:867–871. (PMID: 10.1007/s00268-002-6274-z) Wakai T, Shirai Y, Yokoyama N, Ajioka Y, Watanabe H, Hatakeyama K (2003) Depth of subserosal invasion predicts long-term survival after resection in patients with T2 gallbladder carcinoma. Ann Surg Oncol 10:447–454. (PMID: 10.1245/ASO.2003.06.014) Lundgren L, Muszynska C, Ros A, Persson G, Gimm O, Andersson B, Sandström P (2019) Management of incidental gallbladder cancer in a national cohort. Br J Surg 106:1216–1227. (PMID: 10.1002/bjs.11205) de Savornin Lohman EAJ, van der Geest LG, de Bitter TJJ, Nagtegaal ID, van Laarhoven CJHM, van den Boezem P, van der Post CS, de Reuver PR (2020) Re-resection in incidental gallbladder cancer: survival and the incidence of residual disease. Ann Surg Oncol 27:1132–1142. (PMID: 10.1245/s10434-019-08074-4) Fuks D, Regimbeau JM, Le Treut YP, Bachellier P, Raventos A, Pruvot FR, Chiche L, Farges O (2011) Incidental gallbladder cancer by the AFC-GBC-2009 Study Group. World J Surg 35:1887–1897. Butte JM, Waugh E, Meneses M, Parada H, de la Fuente HA (2010) Incidental gallbladder cancer: analysis of surgical findings and survival. J Surg Oncol 102:620–625. (PMID: 10.1002/jso.21681) Goetze TO, Paolucci V (2010) Adequate extent in radical re-resection of incidental gallbladder carcinoma: analysis of the German Registry. Surg Endosc. 24:2156–2164. (PMID: 10.1007/s00464-010-0914-4) Butte JM, Kingham TP, Gönen M, D’Angelica MI, Allen PJ, Fong Y, DeMatteo RP, Jarnagin WR (2014) Residual disease predicts outcomes after definitive resection for incidental gallbladder cancer. J Am Coll Surg 219:416–429. (PMID: 10.1016/j.jamcollsurg.2014.01.069) Gil L, de Aretxabala X, Lendoire J, Duek F, Hepp J, Imventarza O (2019) Incidental gallbladder cancer: how residual disease affects outcome in two referral HPB centers from South America. World J Surg 43:214–220. (PMID: 10.1007/s00268-018-4762-z) Ethun CG, Postlewait LM, Le N, Pawlik TM, Buettner S, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Jin LX, Weber SM, Salem A, Martin RC, Scoggins C, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Merchant N, Cardona K, Maithel SK (2017) A novel pathology-based preoperative risk score to predict locoregional residual and distant disease and survival for incidental gallbladder cancer: a 10-institution study from the U.S. Extrahepatic Biliary Malignancy Consortium. Ann Surg Oncol 24:1343–1350. Ramos E, Lluis N, Llado L, Torras J, Busquets J, Rafecas A, Serrano T, Mils K, Leiva D, Fabregat J (2020) Prognostic value and risk stratification of residual disease in patients with incidental gallbladder cancer. World J Surg Oncol 18:18. (PMID: 10.1186/s12957-020-1794-2) Sakata J, Kobayashi T, Tajima Y, Ohashi T, Hirose Y, Takano K, Takizawa K, Miura K, Wakai T (2017) Relevance of dissection of the posterior superior pancreaticoduodenal lymph nodes in gallbladder carcinoma. Ann Surg Oncol 24:2474–2481. (PMID: 10.1245/s10434-017-5939-7) Toge K, Sakata J, Hirose Y, Yuza K, Ando T, Soma D, Katada T, Miura K, Takizawa K, Kobayashi T, Wakai T (2019) Lymphatic spread of T2 gallbladder carcinoma: regional lymphadenectomy is required independent of tumor location. Eur J Surg Oncol 45:1446–1452. (PMID: 10.1016/j.ejso.2019.03.038) Japanese Society of Hepato-Biliary-Pancreatic Surgery (2013) General rules for clinical and pathological studies on cancer of the biliary tract, 6th edn. Kanehara & Co., Ltd, Tokyo. Zhu AX, Pawlik TM, Kooby DA, Schefter TE, Vauthey JN (2017) Gallbladder. In: AJCC cancer staging manual, 8th edn. Springer, New York, pp 303–309. Ishihara S, Horiguchi A, Miyakawa S, Endo I, Miyazaki M, Takada T (2016) Biliary tract cancer registry in Japan from 2008 to 2013. J Hepatobiliary Pancreat Sci 23:149–157. (PMID: 10.1002/jhbp.314) Birnbaum DJ, Viganò L, Ferrero A, Langella S, Russolillo N, Capussotti L (2014) Locally advanced gallbladder cancer: which patients benefit from resection? Eur J Surg Oncol 40:1008–1015. (PMID: 10.1016/j.ejso.2013.10.014) Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213. (PMID: 10.1097/01.sla.0000133083.54934.ae) Yao XI, Wang X, Speicher PJ, Hwang ES, Cheng P, Harpole DH, Berry MF, Schrag D, Pang HH (2017) Reporting and guidelines in propensity score analysis: a systematic review of cancer and cancer surgical studies. J Natl Cancer Inst 109:djw323. Vega EA, Vinuela E, Okuno M, Joechle K, Sanhueza M, Diaz C, Jarufe N, Martinez J, Troncoso A, Diaz A, Chun YS, Tzeng CWD, Lee JE, Vauthey JN, Conrad C (2019) Incidental versus non-incidental gallbladder cancer: index cholecystectomy before oncologic re-resection negatively impacts survival in T2b tumors. HPB 21:1046–1056. (PMID: 10.1016/j.hpb.2018.12.006) Pawlik TM, Gleisner AL, Vigano L, Kooby DA, Bauer TW, Frilling A, Adams RB, Staley CA, Trindade EN, Schulick RD, Choti MA, Capussotti L (2007) Incidence of finding residual disease for incidental gallbladder carcinoma: implications for re-resection. J Gastrointest Surg 11:1478–1487. (PMID: 10.1007/s11605-007-0309-6) Shih SP, Schulick RD, Cameron JL, Lillemoe KD, Pitt HA, Choti MA, Campbell KA, Yeo CJ, Talamini MA (2007) Gallbladder cancer: the role of laparoscopy and radical resection. Ann Surg 245:893–901. (PMID: 10.1097/SLA.0b013e31806beec2) Shindoh J, de Aretxabala X, Aloia TA, Roa JC, Roa I, Zimmitti G, Javle M, Conrad C, Maru DM, Aoki T, Vigano L, Ribero D, Kokudo N, Capussotti L, Vauthey JN (2015) Tumor location is a strong predictor of tumor progression and survival in T2 gallbladder cancer: an international multicenter study. Ann Surg 261:733–739. (PMID: 10.1097/SLA.0000000000000728) Lee W, Jeong CY, Jang JY, Kim YH, Roh YH, Kim KW, Kang SH, Yoon MH, Seo HI, Yun SP, Park JI, Jung BH, Shin DH, Choi YI, Moon HH, Chu CW, Ryu JH, Yang K, Park YM, Hong SC (2017) Do hepatic-sided tumors require more extensive resection than peritoneal-sided tumors in patients with T2 gallbladder cancer? Results of a retrospective multicenter study. Surgery 162:515–524. (PMID: 10.1016/j.surg.2017.05.004) Primrose JN, Fox RP, Palmer DH, Malik HZ, Prasad R, Mirza D, Anthony A, Corrie P, Falk S, Finch-Jones M, Wasan H, Ross P, Wall L, Wadsley J, Evans JTR, Stocken D, Praseedom R, Ma YT, Davidson B, Neoptolemos JP, Iveson T, Raftery J, Zhu S, Cunningham D, Garden OJ, Stubbs C, Valle JW, Bridgewater J, Primrose JN, Fox RP, Morement H, Chan O, Rees C, Ma YT, Hickish T, Falk S, Finch-Jones M, Pope I, Corrie P, Crosby T, Sothi S, Sharkland K, Adamson D, Wall L, Evans J, Dent J, Hombaiah U, Iwuji C, Anthoney A, Bridgewater J, Cunningham D, Gillmore R, Ross P, Slater S, Wasan H, Waters J, Valle JW, Palmer D, Malik H, Neoptolemos J, Faluyi O, Sumpter K, Dernedde U, Maduhusudan S, Cogill G, Archer C, Iveson T, Wadsley J, Darby S, Peterson M, Mukhtar AA, Thorpe JG, Bateman A, Tsang D, Cummins S, Nolan L, Beaumont E, Prasad R, Mirza D, Stocken D, Praseedom R, Davidson B, Raftery J, Zhu S, Garden J, Stubbs C, Coxon F (2019) Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study. Lancet Oncol 20:663–673. (PMID: 10.1016/S1470-2045(18)30915-X) Shroff RT, Kennedy EB, Bachini M, Bekaii-Saab T, Crane C, Edeline J, el-Khoueiry A, Feng M, Katz MHG, Primrose J, Soares HP, Valle J, Maithel SK (2019) Adjuvant therapy for resected biliary tract cancer: ASCO clinical practice guideline. J Clin Oncol 37:1015–1027. (PMID: 10.1200/JCO.18.02178) |
فهرسة مساهمة: | Keywords: Gallbladder neoplasms; Incidental gallbladder cancer; Re-resection; Residual disease; Survival |
تواريخ الأحداث: | Date Created: 20210411 Date Completed: 20210924 Latest Revision: 20210924 |
رمز التحديث: | 20231215 |
DOI: | 10.1007/s00423-021-02165-1 |
PMID: | 33839959 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1435-2451 |
---|---|
DOI: | 10.1007/s00423-021-02165-1 |