دورية أكاديمية

Changes of Carotid Intima-Media Thickness After Sleeve Gastrectomy in High Cardiovascular Risk Patients: a Prospective Study.

التفاصيل البيبلوغرافية
العنوان: Changes of Carotid Intima-Media Thickness After Sleeve Gastrectomy in High Cardiovascular Risk Patients: a Prospective Study.
المؤلفون: Salman MA; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Salman AA; Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt. awea844@gmail.com., El Sherbiny M; Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Elkholy S; Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Youssef A; Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Labib S; Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt., El-Din MT; General Surgery Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Monazea KA; General Surgery Department, Al-Azhar Faculty of Medicine for Boys - Assiut, Al-Azhar University, Assiut, Egypt., Tourky MS; Great Western Hospitals NHS Foundation Trust, Swindon, UK., Mikhail HMS; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Maurice KK; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Abdallah A; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Mostafa MS; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Hussein AM; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Abdelsalam AM; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Allah NA; Anatomy and Embryology Department, Faculty of Medicine, Menoufia University, Shibin Al Kawm, Egypt., Ismaeel Saadawy AM; Radiology Department, Faculty of medicine, Ain-Shams University, Cairo, Egypt., Shaaban HE; Gastroenterology Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt., Sarhan MD; General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
المصدر: Obesity surgery [Obes Surg] 2021 Aug; Vol. 31 (8), pp. 3541-3547. Date of Electronic Publication: 2021 Apr 12.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9106714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1708-0428 (Electronic) Linking ISSN: 09608923 NLM ISO Abbreviation: Obes Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: 2006- : New York : Springer Science + Business Media
Original Publication: Oxford, OX, UK : Rapid Communications of Oxford, [1991-
مواضيع طبية MeSH: Cardiovascular Diseases*/etiology , Laparoscopy* , Obesity, Morbid*/surgery, Carotid Intima-Media Thickness ; Egypt ; Gastrectomy ; Heart Disease Risk Factors ; Humans ; Prospective Studies ; Risk Factors
مستخلص: Purpose: There are insufficient data showing the impact of laparoscopic sleeve gastrectomy (LSG) on carotid intima-media thickness (CIMT). Therefore, in the current work, we investigated the improvement of metabolic syndrome and CIMT in patients with obesity after LSG.
Methods: This study involved 120 consecutively selected Egyptian patients with a high cardiovascular risk who underwent LSG and were followed up for 12 months.
Results: CIMT declined from 0.95 ± 0.17 mm to 0.83 ± 0.12 (p < 0.001) after 12 months. In addition, the mean fasting blood glucose and fasting inulin level dropped significantly from 153.3 ± 63.6 to 108.8 ± 33.8 mg/dl and from 23.1 ± 7.1 mU/ml to 14.1 ± 6.4 respectively (p < 0.001). Furthermore, glycated hemoglobin (HbA1c) declined from 7.02 ± 1.7 to 5.5 ± 0.96 (p < 0.001). At the end of the follow-up period, metabolic parameters such as HOMA-IR, C-reactive protein (CRP), fibrinogen, total cholesterol, LDL cholesterol, triglycerides, AST, and ALT decreased significantly from their respective baselines (p value < 0.001). Moreover, the reduction in CIMT showed a strong positive correlation with the degree of weight loss at 6 months and 12 months of follow-up.
Conclusion: LSG led to a substantial decrease in CIMT. Moreover, it significantly impacted cardiovascular risk factors such as obesity, hypertension, insulin resistance, lipid profile, and inflammatory markers.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
References: Bastard J-P, Maachi M, Lagathu C, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006;17:4–12. (PMID: 16613757)
Abushouk AI, El-Husseny MWA, Bahbah EI, et al. Peroxisome proliferator-activated receptors as therapeutic targets for heart failure. Biomed Pharmacother Elsevier. 2017;95:692–700. (PMID: 10.1016/j.biopha.2017.08.083)
Pucci G, Alcidi R, Tap L, et al. Sex- and gender-related prevalence, cardiovascular risk and therapeutic approach in metabolic syndrome: a review of the literature. Pharmacol Res. 2017;120:34–42. (PMID: 10.1016/j.phrs.2017.03.008)
Milić S, Lulić D, Štimac D. Nonalcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations. World J Gastroenterol. 2014;20:9330–7. (PMID: 250713274110564)
Bennett JMH, Mehta S, Rhodes M. Surgery for morbid obesity. Postgrad Med J. 2007;83:8–15. (PMID: 10.1136/pgmj.2006.048868)
Gentileschi P. Laparoscopic sleeve gastrectomy as a primary operation for morbid obesity: experience with 200 patients. Gastroenterol Res Pract. 2012;2012:1–4. (PMID: 10.1155/2012/801325)
Fuks D, Verhaeghe P, Brehant O, et al. Results of laparoscopic sleeve gastrectomy: a prospective study in 135 patients with morbid obesity. Surgery. 2009;145:106–13. (PMID: 10.1016/j.surg.2008.07.013)
Lombardo V, Baratta R, Giannone G. Laparoscopic sleeve gastrectomy for morbid obesity. Our initial experience. Ann Ital Chir. 81:17–20.
Rosenthal RJ. International sleeve gastrectomy expert panel consensus statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis. 2012;8:8–19. (PMID: 10.1016/j.soard.2011.10.019)
Emadeldin D, Ramadan A, Fala SY, et al. Disease modifying efficacy of memantine in Alzheimer’s disease: a pooled analysis of 13 randomized controlled trials. J Neurol Sci. 2017;381:767. (PMID: 10.1016/j.jns.2017.08.2166)
Eikendal ALM, Groenewegen KA, Anderson TJ, et al. Common carotid intima-media thickness relates to cardiovascular events in adults aged <45 years. Hypertension. 2015;65:707–13. (PMID: 10.1161/HYPERTENSIONAHA.114.04658)
Kastelein JJP, de Groot E. Ultrasound imaging techniques for the evaluation of cardiovascular therapies. Eur Heart J. 2008;29:849–58. (PMID: 10.1093/eurheartj/ehn070)
Lupoli R, Di Minno MND, Guidone C, et al. Effects of bariatric surgery on markers of subclinical atherosclerosis and endothelial function: a meta-analysis of literature studies. Int J Obes. 2016;40:395–402. (PMID: 10.1038/ijo.2015.187)
Von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology ( STROBE ) statement : guidelines for reporting observational studies *. Int J Surg Elsevier Ltd. 2014;12:1495–9.
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation. 2005. p. 2735–52.
Surgeons E. Guidelines for laparoscopic resection of curable colon and rectal cancer. Dis Colon Rectum. 2006:1–9.
Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care. 2004;27:1487–95. (PMID: 10.2337/diacare.27.6.1487)
Brombacher PJ. Lehrbuch der Klinischen Chemie und Pathobiochemie (in German). Clin Chim Acta. 1988;175:118–9. (PMID: 10.1016/0009-8981(88)90046-0)
Lorenz MW, Polak JF, Kavousi M, et al. Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data. Lancet. 2012;379:2053–62. (PMID: 10.1016/S0140-6736(12)60441-3)
Lorenz MW, Markus HS, Bots ML, et al. Prediction of clinical cardiovascular events with carotid intima-media thickness. Circulation. 2007;115:459–67. (PMID: 10.1161/CIRCULATIONAHA.106.628875)
Altin C, Erol V, Aydin E, et al. Impact of weight loss on epicardial fat and carotid intima media thickness after laparoscopic sleeve gastrectomy: a prospective study. Nutr Metab Cardiovasc Dis. 2018;28:501–9. (PMID: 10.1016/j.numecd.2018.02.001)
Gómez-Martin JM, Aracil E, Galindo J, et al. Improvement in cardiovascular risk in women after bariatric surgery as measured by carotid intima-media thickness: comparison of sleeve gastrectomy versus gastric bypass. Surg Obes Relat Dis Elsevier. 2017;13:848–54. (PMID: 10.1016/j.soard.2017.01.040)
Cobeta P, Osorio A, Cuadrado-Ayuso M, et al. Sleeve gastrectomy and gastric bypass decrease the carotid intima-media thickness in obese men: association with weight loss, cardiovascular risk factors, and circulating testosterone. Obes Surg. 2020;30:851–9. (PMID: 10.1007/s11695-020-04405-7)
Karason K, Wikstrand J, Sjöström L, et al. Weight loss and progression of early atherosclerosis in the carotid artery: a four-year controlled study of obese subjects. Int J Obes. 1999;23:948–56. (PMID: 10.1038/sj.ijo.0801024)
Lundby-Christensen L, Tarnow L, Hansen DL, et al. Carotid intima-media thickness is reduced 12 months after gastric bypass surgery in obese patients with type 2 diabetes or impaired glucose tolerance. J Diabetes Complicat. 2014;28:517–22. (PMID: 10.1016/j.jdiacomp.2014.03.005)
Salman MA, Salman AA, Nafea MA, et al. Study of changes of obesity-related inflammatory cytokines after laparoscopic sleeve gastrectomy. ANZ J Surg [Internet]. Blackwell Publishing; 2019 [cited 2020 Mar 22];89:1265–9. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/ans.15427.
Salman MA, Abdallah A, Mikhail HMS, et al. Long-term impact of mini-gastric bypass on inflammatory cytokines in cohort of morbidly obese patients: a prospective study. Obes Surg. 2020;30:2338–44. (PMID: 10.1007/s11695-020-04471-x)
Asha K, Sharma SB, Singal A, et al. Association of carotid intima-media thickness with leptin and apoliprotein b/apoliprotein a-I ratio reveals imminent predictors of subclinical atherosclerosis in psoriasis patients. Acta Med (Hradec Kralove). 2014;57:21–7. (PMID: 10.14712/18059694.2014.4)
Strain GW, Saif T, Ebel F, et al. Lipid profile changes in the severely obese after laparoscopic sleeve gastrectomy (LSG), 1, 3, and 5 years after surgery. Obes Surg. 2015;25:285–9. (PMID: 10.1007/s11695-014-1351-6)
فهرسة مساهمة: Keywords: Bariatric surgery; Carotid intima-media thickness; Laparoscopic sleeve gastrectomy; Metabolic syndrome
تواريخ الأحداث: Date Created: 20210412 Date Completed: 20210720 Latest Revision: 20211222
رمز التحديث: 20221213
DOI: 10.1007/s11695-021-05419-5
PMID: 33844173
قاعدة البيانات: MEDLINE
الوصف
تدمد:1708-0428
DOI:10.1007/s11695-021-05419-5