دورية أكاديمية
أعرض في EDS

Severe Acute Respiratory Syndrome Coronavirus 2 P.2 Lineage Associated with Reinfection Case, Brazil, June-October 2020.

التفاصيل البيبلوغرافية
العنوان: Severe Acute Respiratory Syndrome Coronavirus 2 P.2 Lineage Associated with Reinfection Case, Brazil, June-October 2020.
المؤلفون: Resende PC, Bezerra JF, Teixeira Vasconcelos RH, Arantes I, Appolinario L, Mendonça AC, Paixao AC, Duarte AC, Silva T, Rocha AS, Lima ABM, Pauvolid-Corrêa A, Motta FC, Teixeira DLF, de Oliveira Carneiro TF, Neto FPF, Herbster ID, Leite AB, Riediger IN, do Carmo Debur M, Naveca FG, Almeida W, Livorati M, Bello G, Siqueira MM
المصدر: Emerging infectious diseases [Emerg Infect Dis] 2021 Jul; Vol. 27 (7), pp. 1789-1794. Date of Electronic Publication: 2021 Apr 22.
نوع المنشور: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Adult ; Bayes Theorem ; Brazil/epidemiology ; Humans ; Reinfection
مستخلص: A 37-year-old healthcare worker from the northeastern region of Brazil experienced 2 clinical episodes of coronavirus disease. Infection with severe acute respiratory syndrome coronavirus 2 was confirmed by reverse transcription PCR in samples collected 116 days apart. Whole-genome sequencing revealed that the 2 infections were caused by the most prevalent lineage in Brazil, B.1.1.33, and the emerging lineage P.2. The first infection occurred in June 2020; Bayesian analysis suggests reinfection at some point during September 14-October 11, 2020, a few days before the second episode of coronavirus disease. Of note, P.2 corresponds to an emergent viral lineage in Brazil that contains the mutation E484K in the spike protein. The P.2 lineage was initially detected in the state of Rio de Janeiro, and since then it has been found throughout the country. Our findings suggest not only a reinfection case but also geographic dissemination of the emerging Brazil clade P.2.
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فهرسة مساهمة: Keywords: Brazil; COVID-19; P.2; SARS-CoV-2; coronavirus disease; reinfection; respiratory infections; secondary infection; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses
تواريخ الأحداث: Date Created: 20210422 Date Completed: 20210624 Latest Revision: 20231107
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8237896
DOI: 10.3201/eid2707.210401
PMID: 33883059
قاعدة البيانات: MEDLINE
الوصف
تدمد:1080-6059
DOI:10.3201/eid2707.210401