دورية أكاديمية
Living Alone and Clinical Outcomes in Patients With Heart Failure With Preserved Ejection Fraction.
العنوان: | Living Alone and Clinical Outcomes in Patients With Heart Failure With Preserved Ejection Fraction. |
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المؤلفون: | Zhu W; From the Department of Cardiology (Zhu, Y. Wu, Zhou, Liang, Xue, Z. Wu, D. Wu, He, Dong, Liu), the First Affiliated Hospital of Sun Yat-sen University; NHC Key Laboratory of Assisted Circulation (Zhu, Y. Wu, Zhou, Liang, Xue, Z. Wu, D. Wu, He, Dong, Liu), Sun Yat-sen University; and National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases (Dong, Liu), Guangzhou, PR China., Wu Y, Zhou Y, Liang W, Xue R, Wu Z, Wu D, He J, Dong Y, Liu C |
المصدر: | Psychosomatic medicine [Psychosom Med] 2021 Jun 01; Vol. 83 (5), pp. 470-476. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0376505 Publication Model: Print Cited Medium: Internet ISSN: 1534-7796 (Electronic) Linking ISSN: 00333174 NLM ISO Abbreviation: Psychosom Med Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Baltimore [etc.] |
مواضيع طبية MeSH: | Heart Failure*/epidemiology, Female ; Heart ; Hospitalization ; Humans ; Male ; Mineralocorticoid Receptor Antagonists ; Prognosis ; Stroke Volume |
مستخلص: | Objective: In patients with heart failure with preserved ejection fraction (HFpEF), whether living alone could contribute to a poor prognosis remains unknown. We sought to investigate the association of living alone with clinical outcomes in patients with HFpEF. Methods: Symptomatic patients with HFpEF with a follow-up of 3.3 years (data collected from August 2006 to June 2013) in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial were classified as patients living alone and those living with others. The primary outcome was defined as a composite of cardiovascular death, aborted cardiac arrest, or HF hospitalization. Results: A total of 3103 patients with HFpEF were included; 25.2% of them were living alone and were older, predominantly female, and less likely to be White and have more comorbidities compared with the other patients. After multivariate adjustment for confounders, living alone was associated with increased risks of HF hospitalization (hazard ratio [HR] = 1.29, 95% confidence interval [CI] = 1.03-1.61) and any hospitalization (HR = 1.26, 95% CI = 1.12-1.42). A significantly increased risk of any hospitalization (HR = 1.16, 95% CI = 1.01-1.34) was also observed in the Americas-based sample. In addition, each year increase in age, female sex, non-White race, New York Heart Association functional classes III and IV, dyslipidemia, and chronic obstructive pulmonary disease were independently associated with living alone. Conclusions: We assessed the effect of living arrangement status on clinical outcomes in patients with HFpEF and suggested that living alone was associated with an independent increase in any hospitalization.Clinical Trial Registration: ClinicalTrials.gov identifier: NCT00094302. (Copyright © 2021 by the American Psychosomatic Society.) |
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سلسلة جزيئية: | ClinicalTrials.gov NCT00094302 |
المشرفين على المادة: | 0 (Mineralocorticoid Receptor Antagonists) |
تواريخ الأحداث: | Date Created: 20210426 Date Completed: 20211020 Latest Revision: 20220531 |
رمز التحديث: | 20231215 |
DOI: | 10.1097/PSY.0000000000000945 |
PMID: | 33901053 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1534-7796 |
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DOI: | 10.1097/PSY.0000000000000945 |