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Preoperative Diagnosis Failure for a Rare Gastric Collision Tumor: A Case Report.

التفاصيل البيبلوغرافية
العنوان: Preoperative Diagnosis Failure for a Rare Gastric Collision Tumor: A Case Report.
المؤلفون: Elshaer RE; Department of Pathology, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt., Elgammal ER; Department of Surgery, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt., Elmistekawy AM; Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt., Ghannam WA; Department of Pathology, Faculty of Medicine, Suez University, Suez 43533, Egypt., Elshamy AE; Department of Radiology, Faculty of Medicine, Al-Azhar University, New Damietta 71524, Egypt., Abed SY; Department of Respiratory Care, College of Applied Medical Science in Jubail, Imam Abdulrahman Bin Faisal University, Jubail 35816, Saudi Arabia., Zaitone SA; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.; Department of Pharmacology & Toxicology, Faculty of Pharmacy, University of Tabuk, Tabuk 47512, Saudi Arabia.
المصدر: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2021 Apr 01; Vol. 11 (4). Date of Electronic Publication: 2021 Apr 01.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101658402 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4418 (Print) Linking ISSN: 20754418 NLM ISO Abbreviation: Diagnostics (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2011]-
مستخلص: Gastrointestinal stromal tumors (GISTs) are common mesenchymal tumors of the gastrointestinal tract (GIT), usually occur as a solitary neoplasm. Inflammatory florid polyp (IFP) is a solitary rare benign lesion of the gastrointestinal tract, mainly occur in the gastric antrum, whose atypical presentation can mimic GISTs or other malignant tumors, therefore the synchronous occurrence of GISTs and IFP is extremely rare. We had a case of a 58-year-old man that was presented with recurrent epigastric pain and recurrent melena. Upper endoscopic examination revealed a large polypoid antrum polyp measured 7 cm at greatest dimension with focal ulceration. Clinical and radiological features did not reach the definite diagnosis until histopathological evaluation with immunohistochemical analysis was performed. Surgical intervention is recommended and partial gastrectomy was done with wide resection margins. Histological examination revealed two distinct GISTs and IFP parts presenting a collision tumor that showed spindle and epitheloid cells consistent with GISTs with histological features of florid polyp showed a characteristic perivascular onion-skin arrangement of spindle cells with dense chronic inflammatory infiltrate including eosinophils and lymphocytes. Immunohistochemical studies have been done and revealed an association between GISTs and IFP. To the best of our knowledge, this is the first case of a collision tumor consisting of a GIST and an IFP arising in the stomach. In conclusion, the gastrointestinal stromal tumor is the comments mesenchymal tumor of GIT and IFP is a rare benign lesion of GIT therefore association between GIST and IFP as a collision tumor is extremely rare.
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فهرسة مساهمة: Keywords: GISTs; case report; gastric neoplasm; inflammatory florid polyp
تواريخ الأحداث: Date Created: 20210430 Latest Revision: 20210502
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8066249
DOI: 10.3390/diagnostics11040633
PMID: 33915830
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-4418
DOI:10.3390/diagnostics11040633