مراجعة
IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature.
العنوان: | IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature. |
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المؤلفون: | Chang EK; Division of Hematology, Oncology and Blood & Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA., Smith-Cohn MA; Department of Neurology, Johns Hopkins Hospital, Baltimore, MD, USA.; Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Tamrazi B; Department of Radiology, Children's Hospital Los Angeles, Los Angeles, CA, USA., Ji J; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, USA., Krieger M; Division of Neurosurgery, Children's Hospital Los Angeles, Los Angeles, CA, USA., Holdhoff M; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Eberhart CG; Department of Pathology, Johns Hopkins Hospital, Baltimore, MD, USA., Margol AS; Division of Hematology, Oncology and Blood & Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA., Cotter JA; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, USA. |
المصدر: | Brain pathology (Zurich, Switzerland) [Brain Pathol] 2021 Jul; Vol. 31 (4), pp. e12959. Date of Electronic Publication: 2021 May 07. |
نوع المنشور: | Case Reports; Letter; Research Support, Non-U.S. Gov't; Review |
اللغة: | English |
بيانات الدورية: | Publisher: International Society of Neuropathology Country of Publication: Switzerland NLM ID: 9216781 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-3639 (Electronic) Linking ISSN: 10156305 NLM ISO Abbreviation: Brain Pathol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Zürich, Switzerland : International Society of Neuropathology, [1990- |
مواضيع طبية MeSH: | Brain Neoplasms/*genetics , Brain Neoplasms/*pathology , Glioma/*genetics , Glioma/*pathology , Isocitrate Dehydrogenase/*genetics, Adult ; Brain Stem/pathology ; Brain Stem Neoplasms/diagnosis ; Brain Stem Neoplasms/genetics ; Brain Stem Neoplasms/pathology ; Glioma/diagnosis ; Humans ; Male ; Mutation/genetics ; Young Adult |
مستخلص: | Isocitrate dehydrogenase (IDH) mutations are rare in pediatric and adolescent gliomas. We recently identified three adolescent/young adult (AYA) patients with IDH-mutant low grade gliomas of the brainstem with several key clinicopathologic and molecular features in common. We discuss these three cases and review the current literature. (© 2021 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology.) |
References: | J Neurooncol. 2012 May;108(1):187-93. (PMID: 22367412) Acta Neuropathol. 2018 Jul;136(1):153-166. (PMID: 29687258) Acta Neuropathol. 2015 May;129(5):669-78. (PMID: 25752754) J Neuropathol Exp Neurol. 2012 Jul;71(7):631-9. (PMID: 22710963) Cancer Cell. 2020 Apr 13;37(4):569-583.e5. (PMID: 32289278) Int J Cancer. 2020 Jun 15;146(12):3385-3396. (PMID: 31613986) Asian J Neurosurg. 2018 Apr-Jun;13(2):414-417. (PMID: 29682047) Acta Neuropathol. 2020 Oct;140(4):569-581. (PMID: 32776277) Acta Neuropathol. 2012 Sep;124(3):449-51. (PMID: 22772980) Nat Commun. 2020 Jun 17;11(1):3077. (PMID: 32555164) |
فهرسة مساهمة: | Keywords: IDH; brain biopsy; brainstem glioma; isocitrate dehydrogenase; low grade glioma; young adult |
المشرفين على المادة: | EC 1.1.1.41 (Isocitrate Dehydrogenase) |
تواريخ الأحداث: | Date Created: 20210507 Date Completed: 20220202 Latest Revision: 20220202 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC8412065 |
DOI: | 10.1111/bpa.12959 |
PMID: | 33960568 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1750-3639 |
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DOI: | 10.1111/bpa.12959 |