دورية أكاديمية
أعرض في EDS

A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal crisis: a case report.

التفاصيل البيبلوغرافية
العنوان: A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal crisis: a case report.
المؤلفون: Genetu A; Department of Internal Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia. aberegenetu45@gmail.com., Anemen Y; Department of Internal Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Abay S; Department of Internal Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Bante SA; Department of Midwifery, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Mihrete KM; Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
المصدر: Journal of medical case reports [J Med Case Rep] 2021 May 08; Vol. 15 (1), pp. 229. Date of Electronic Publication: 2021 May 08.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, [2007-
مواضيع طبية MeSH: Adrenal Insufficiency*/diagnosis , Adrenal Insufficiency*/drug therapy , Adrenal Insufficiency*/etiology , Hypopituitarism*/diagnosis , Hypopituitarism*/drug therapy , Hypopituitarism*/etiology, Acute Disease ; Female ; Hormone Replacement Therapy ; Humans ; Middle Aged ; Pituitary Gland ; Pregnancy
مستخلص: Background: Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis.
Case Presentation: We describe the case of a 45-year-old Ethiopian woman who presented with generalized fatigue for 18 years which progressed to anorexia, nausea, vomiting, diarrhea, and abdominal pain of 6 years' duration, for which she was treated symptomatically throughout these years. Complete clinical evaluation, endocrine studies, and pituitary magnetic resonance scan revealed hypopituitarism secondary to Sheehan's syndrome. She had significant improvement noted following the commencement of hormone replacement therapy.
Conclusion: Previous case reports describe patients being diagnosed after one or more complications from long-term panhypopituitarism. The present case illustrates that undiagnosed Sheehan's syndrome is associated with long-term morbidity, and we want to emphasize that a high index of suspicion is crucial for the early diagnosis of the syndrome in routine clinical visits in order to prevent complications arising with delayed diagnosis. Awareness among clinicians is also essential so that such cases are not overlooked, especially in developing nations, where home delivery is still common and obstetric care is limited.
References: Iran J Med Sci. 2015 Jan;40(1):73-6. (PMID: 25648343)
BMJ. 2004 Jul 24;329(7459):218-9. (PMID: 15271834)
Indian J Endocrinol Metab. 2011 Sep;15 Suppl 3:S203-7. (PMID: 22029025)
Lancet. 2003 Feb 8;361(9356):520-2. (PMID: 12583962)
Gynecol Endocrinol. 2016 Nov;32(11):904-907. (PMID: 27252045)
Clin Endocrinol (Oxf). 2000 Mar;52(3):295-303. (PMID: 10718827)
Isr J Med Sci. 1994 Nov;30(11):826-9. (PMID: 7982772)
Drugs. 2000 Jan;59(1):93-106. (PMID: 10718101)
Ann Hematol. 2004 May;83(5):309-12. (PMID: 15064859)
Pituitary. 2003;6(4):181-8. (PMID: 15237929)
Eur J Endocrinol. 2014 Mar 08;170(4):477-86. (PMID: 24394725)
Nat Rev Dis Primers. 2016 Dec 22;2:16092. (PMID: 28004764)
Endocr J. 2003 Jun;50(3):297-301. (PMID: 12940458)
Lancet. 1998 Jul 11;352(9122):127-34. (PMID: 9672293)
Clin Endocrinol (Oxf). 2011 Jan;74(1):9-20. (PMID: 21044119)
BMJ Case Rep. 2014 May 19;2014:. (PMID: 24842349)
BMJ Case Rep. 2012 Nov 06;2012:. (PMID: 23131607)
Aust N Z J Med. 1993 Feb;23(1):26-31. (PMID: 8460969)
Gynecol Endocrinol. 2000 Apr;14(2):99-104. (PMID: 10836196)
J Obstet Gynaecol Res. 2014 Jan;40(1):46-52. (PMID: 23945005)
Gynecol Endocrinol. 2006 May;22(5):279-83. (PMID: 16785150)
Br J Obstet Gynaecol. 1987 Oct;94(10):998-9. (PMID: 3689732)
Am J Obstet Gynecol. 1978 Oct 15;132(4):348-53. (PMID: 212951)
Acta Biomed. 2009 Apr;80(1):73-6. (PMID: 19705625)
فهرسة مساهمة: Keywords: Adrenal crisis; Case report; Central hypothyroidism; Panhypopituitarism; Postpartum hemorrhage; Secondary adrenal insufficiency; Sheehan’s syndrome
تواريخ الأحداث: Date Created: 20210508 Date Completed: 20210512 Latest Revision: 20210512
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8105925
DOI: 10.1186/s13256-021-02827-0
PMID: 33962642
قاعدة البيانات: MEDLINE
الوصف
تدمد:1752-1947
DOI:10.1186/s13256-021-02827-0