دورية أكاديمية
أعرض في EDS

Low Rate of Intrathecal Baclofen Pump Catheter-Related Complications: Long-Term Study in Over 100 Adult Patients Associated With Reinforced Catheter.

التفاصيل البيبلوغرافية
العنوان: Low Rate of Intrathecal Baclofen Pump Catheter-Related Complications: Long-Term Study in Over 100 Adult Patients Associated With Reinforced Catheter.
المؤلفون: Feller CN; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Awad AJ; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine., Nelson MES; Department of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Ketchum N; Department of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Pahapill PA; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Neurosurgery, U.S. Department of Veterans Affairs Medical Center, Milwaukee, Wisconsin, USA.
المصدر: Neuromodulation : journal of the International Neuromodulation Society [Neuromodulation] 2021 Oct; Vol. 24 (7), pp. 1176-1180. Date of Electronic Publication: 2021 May 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9804159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-1403 (Electronic) Linking ISSN: 10947159 NLM ISO Abbreviation: Neuromodulation Subsets: MEDLINE
أسماء مطبوعة: Publication: 2022- : [New York] : Elsevier
Original Publication: Malden, MA : Blackwell Science, c1998-
مواضيع طبية MeSH: Baclofen*/adverse effects , Muscle Relaxants, Central*/adverse effects, Adult ; Catheters/adverse effects ; Female ; Humans ; Infusion Pumps, Implantable/adverse effects ; Injections, Spinal/adverse effects ; Male ; Middle Aged ; Muscle Spasticity/drug therapy ; Muscle Spasticity/etiology ; Retrospective Studies
مستخلص: Objectives: Intrathecal baclofen (ITB) is a cost-effective therapy for patients with severe spasticity. The most common complications are catheter-related complications (CRCs) including kinking/occlusion, blockage, migration, fracture, disconnection, and CSF leak. Our objective was to determine the CRC rate in a large cohort of adults with newly implanted ITB pump systems with polymer reinforced silicone catheters.
Materials and Methods: This is a retrospective study of a prospectively maintained database consisting of patients who had undergone implantation of ITB pump systems with Ascenda (Medtronic, Minneapolis) catheters from 2013 to 2020. Over this seven-year period, 141 patients underwent ITB pump system implantations; 126 of which had a minimum of one-year follow-up.
Results: The 126 patients with a minimum of one year follow-up (average 43 month; range 12-89), had an average age of 51 years (63% male). Severe spasticity was due to spinal cord injury (38%), traumatic brain injury (15%), cerebral palsy (13%), multiple sclerosis (11%), stroke (10%), and other (13%). Nine (7.1%) CRCs occurred in 7 (5.6%) patients (median 6 mo. post-implant): 5 intrathecal catheter occlusions (range 3-52 months post-implant), two fractures in one patient (6 months), one disconnection at the catheter pump interface (2 months), and one due to kinking at 84 months No migrations occurred.
Conclusions: Reported CRCs have been high for ITB pump systems. Ours is the first large cohort, long-term study of CRCs related to reinforced catheters; additionally, our low CRC rate compares favorably to previously published data. Thus, implantation of reinforced catheters may be associated with a low CRC rate.
(© 2021 International Neuromodulation Society.)
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فهرسة مساهمة: Keywords: Catheter-related complications; intrathecal baclofen pump; retrospective study; spasticity
المشرفين على المادة: 0 (Muscle Relaxants, Central)
H789N3FKE8 (Baclofen)
تواريخ الأحداث: Date Created: 20210511 Date Completed: 20211026 Latest Revision: 20220210
رمز التحديث: 20231215
DOI: 10.1111/ner.13412
PMID: 33974333
قاعدة البيانات: MEDLINE
الوصف
تدمد:1525-1403
DOI:10.1111/ner.13412