دورية أكاديمية
أعرض في EDS

Re-positive of SARS-CoV-2 test is common in COVID-19 patients after hospital discharge. Data from high standard post-discharge quarantined patients in Macao SAR, China.

التفاصيل البيبلوغرافية
العنوان: Re-positive of SARS-CoV-2 test is common in COVID-19 patients after hospital discharge. Data from high standard post-discharge quarantined patients in Macao SAR, China.
المؤلفون: Wong CL; Macao Academy of Medicine, Centro Hospitalar Conde de São Januário, Health Bureau, Macao SAR, China., Lei SK; Macao Academy of Medicine, Centro Hospitalar Conde de São Januário, Health Bureau, Macao SAR, China., Lei CI; Department of Medicine, Centro Hospitalar Conde de São Januário, Health Bureau, Macao SAR, China., Lo IL; Department of Respiratory Medicine, Centro Hospitalar Conde de São Januário, Health Bureau, Macao SAR, China., Lam C; Center for Disease Control and Prevention, Health Bureau, Macao SAR, China., Leong IH; Center for Disease Control and Prevention, Health Bureau, Macao SAR, China.
المصدر: PeerJ [PeerJ] 2021 Apr 23; Vol. 9, pp. e11170. Date of Electronic Publication: 2021 Apr 23 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Print ISSN: 2167-8359 (Print) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Corte Madera, CA : PeerJ Inc.
مستخلص: During the pandemic of COVID-19, Macau faces tremendous pressure because it is a famous gambling and tourism city with the world's highest population density. The Macau government implemented decisive public health intervention to control the transmission of COVID-19, and there were only two independent outbreaks in Macau. In the second outbreak, all 35 cases were infected in foreign countries. They were quarantined in airborne infection isolation rooms for at least 14 days with reverse transcription-polymerase chain reaction (RT-PCR) tests after hospital discharge. Twelve (34.3%) of them had re-positive SARS-CoV-2 test results, and none of them presented any COVID-19 signs or symptoms during the entire quarantine period. In this study, the re-positive patients were more likely to be diagnosed in the early stage of the disease with a longer hospital stay. Virus re-infection is impossible in this high standard isolation setting, and reactivation is also unlikely, so that residual virus nucleic acid should be the possible reason for this phenomenon. Due to limited data about the risk of re-positive patients, it is better to quarantine patients after discharge for a prolonged period with repeat RT-PCR tests to minimize the community's potential risk, particularly in the regions with relative plenty of resources and low community infection rate such as Macau.
Competing Interests: The authors declare there are no competing interests.
(©2021 Wong et al.)
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فهرسة مساهمة: Keywords: COVID-19; Discharge; Macau; Quarantine; RT-PCR detection; Re-positive
تواريخ الأحداث: Date Created: 20210513 Latest Revision: 20210514
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8074836
DOI: 10.7717/peerj.11170
PMID: 33981492
قاعدة البيانات: MEDLINE
الوصف
تدمد:2167-8359
DOI:10.7717/peerj.11170