دورية أكاديمية
أعرض في EDS

Combined Oral Contraceptive Pill-Induced Hypertension and Hypertensive Disorders of Pregnancy: Shared Mechanisms and Clinical Similarities.

التفاصيل البيبلوغرافية
العنوان: Combined Oral Contraceptive Pill-Induced Hypertension and Hypertensive Disorders of Pregnancy: Shared Mechanisms and Clinical Similarities.
المؤلفون: Gunaratne MDSK; Division of Nephrology and Hypertension, Department of Internal Medicine, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN, USA., Thorsteinsdottir B; Mayo Clinic KERN Center for the Science of Health Care Delivery and the Knowledge Evaluation and Research Unit, Division of Community Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Garovic VD; Division of Nephrology and Hypertension, Department of Internal Medicine, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN, USA. Garovic.Vesna@mayo.edu.
المصدر: Current hypertension reports [Curr Hypertens Rep] 2021 May 13; Vol. 23 (5), pp. 29. Date of Electronic Publication: 2021 May 13.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review
اللغة: English
بيانات الدورية: Publisher: Current Science, Inc Country of Publication: United States NLM ID: 100888982 Publication Model: Electronic Cited Medium: Internet ISSN: 1534-3111 (Electronic) Linking ISSN: 15226417 NLM ISO Abbreviation: Curr Hypertens Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Philadelphia, PA : Current Science, Inc., c1999-
مواضيع طبية MeSH: Cardiovascular System* , Hypertension, Pregnancy-Induced*/chemically induced, Contraceptives, Oral, Combined/adverse effects ; Female ; Humans ; Pregnancy ; Renin-Angiotensin System ; Risk Factors
مستخلص: Purpose of Review: Oral contraceptive pill-induced hypertension (OCPIH) and hypertensive disorders in pregnancy (HDP) share common risk factors and pathophysiological mechanisms, yet the bidirectional relationship between these two conditions is not well-established. We review and describe OCPIH and HDP to better understand how hormonal and metabolic imbalances affect hypertension.
Recent Findings: Oral contraceptive pills continue to be a popular method of contraception, with an incidence of OCPIH ranging from 1-8.5% among OCP users. HDP have an incidence of 5-10% of all pregnancies in the USA and have been shown to be a powerful predictor of lifetime adverse cardiovascular outcomes, including future hypertension. OCPIH and HDP share common risk factors such as age, BMI, past personal and family history of hypertension, as well as pathogenic mechanisms, including alterations in hormonal metabolism and the renin angiotensin aldosterone system; imbalance of vasodilator-vasoconstrictor compounds; and changes in the cardiovascular system. Future research should address additional potential mechanisms that underlie hypertension in these two conditions where endocrine changes, either physiological (pregnancy) or iatrogenic (use of OCP), play a role. This may lead to novel, targeted treatment options to improve hypertension management and overall cardiovascular risk profile management in this subset of young female patients.
معلومات مُعتمدة: K23 AG051679 United States AG NIA NIH HHS; R01 HL136348 United States HL NHLBI NIH HHS
فهرسة مساهمة: Keywords: Drug-induced hypertension; Gestational hypertension; Hormone treatment; Preeclampsia
المشرفين على المادة: 0 (Contraceptives, Oral, Combined)
تواريخ الأحداث: Date Created: 20210513 Date Completed: 20210520 Latest Revision: 20220514
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC8127613
DOI: 10.1007/s11906-021-01147-4
PMID: 33982185
قاعدة البيانات: MEDLINE
الوصف
تدمد:1534-3111
DOI:10.1007/s11906-021-01147-4