دورية أكاديمية
أعرض في EDS

Elemental plasma content and urinary excretion in vineyard farmers occupationally exposed to pesticides in southern Brazil.

التفاصيل البيبلوغرافية
العنوان: Elemental plasma content and urinary excretion in vineyard farmers occupationally exposed to pesticides in southern Brazil.
المؤلفون: Lini RS; Postgraduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Paraná, Brazil., Aguera RG; Postgraduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Paraná, Brazil., Hoeltgebaum D; Postgraduate Program in Health Sciences, State University of Maringá, Maringá, Paraná, Brazil., Paniz FP; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Santo André, São Paulo, Brazil., Pedron T; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Santo André, São Paulo, Brazil., Capelari S; Paraná Rural Development Institute (IDR - PR), Marialva, Paraná, Brazil., Monteiro LR; Centro de Química e Meio Ambiente (CEQMA), Instituto de Pesquisas Energéticas e Nucleares (IPEN/CNEN-SP), São Paulo, Brazil., Machinski Junior M; Postgraduate Program in Health Sciences, State University of Maringá, Maringá, Paraná, Brazil., Nerilo SB; Ingá University Center (Uningá), Maringá, Paraná, Brazil., Batista BL; Center for Natural Sciences and Humanities, Federal University of ABC (UFABC), Santo André, São Paulo, Brazil., de Oliveira MLF; Poison Control Center at Maringá University Hospital, Maringá, Paraná, Brazil., Mossini SAG; Postgraduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Paraná, Brazil. sagmossini@uem.br.; Department of Health Basic Sciences, Laboratory of Toxicology, State University of Maringa, Avenue Colombo no 5790, Maringa, PR, 87020-900, Brazil. sagmossini@uem.br.
المصدر: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Oct; Vol. 28 (37), pp. 51841-51853. Date of Electronic Publication: 2021 May 15.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 9441769 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1614-7499 (Electronic) Linking ISSN: 09441344 NLM ISO Abbreviation: Environ Sci Pollut Res Int Subsets: MEDLINE
أسماء مطبوعة: Publication: <2013->: Berlin : Springer
Original Publication: Landsberg, Germany : Ecomed
مواضيع طبية MeSH: Pesticides* , Trace Elements*/analysis, Brazil ; Cross-Sectional Studies ; Farmers ; Farms ; Humans
مستخلص: This is a cross-sectional study with data and biological material collection from vineyard farmers in southern Brazil. An interview was carried out through a questionnaire developed according to the reference guide of the state government. Plasma and urine samples were screened for Aluminum, Chromium, Manganese, Copper, Nickel, Cobalt, Zinc, Arsenic, Selenium, Cadmium, Antimony, Barium, Mercury, Lead and Uranium, with a technique for fast determination of these elemental contents in biological material utilizing dynamic reaction cell inductively coupled mass spectrometry. Principal component analysis was used to identify associations between these elemental contents in biological samples and the information obtained from the interviews. The farmers showed some trace elements in plasma and urine at a higher concentration than unexposed populations from other studies. This study highlights recent findings of trace elements in biological material and their association with characteristics of pesticide use. In addition, it also contributes to the gap in the literature regarding trace elements content in plasma and urine of workers exposed to pesticides.
(© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
References: Adamkovicova M, Toman R, Cabaj M, Massanyi P, Martiniakova M, Omelka R, Krajcovicova V, Duranova H (2014) Effects of subchronic exposure to cadmium and diazinon on testis and epididymis in rats. Sci World J 2014:632581–632589. https://doi.org/10.1155/2014/632581. (PMID: 10.1155/2014/632581)
ADAPAR: Agência de Defesa Agropecuária do Paraná (2020) Agrotóxicos no Paraná. http://celepar07web.pr.gov.br/agrotoxicos/bulas.asp . Accessed 21 Oct 2020.
Alkhader AMF (2015) The impact of phosphorus fertilizers on heavy metals content of soils and vegetables grown on selected farms in Jordan. Agrotechnology 5:137. https://doi.org/10.4172/2168-9881.1000137. (PMID: 10.4172/2168-9881.1000137)
Alves JS, da Silva FR, da Silva GF, Salvador M, Kvitko K, Rohr P et al (2016) Investigation of potential biomarkers for the early diagnosis of cellular stability after the exposure of agricultural workers to pesticides. An Acad Bras Cienc 88(1):349–360. https://doi.org/10.1590/0001-3765201520150181. (PMID: 10.1590/0001-3765201520150181)
ANVISA: Agência Nacional de Vigilância Sanitária (2015) Consulta Pública n° 87, de 2 de outubro de 2015. http://inmetro.gov.br/barreirastecnicas/pontofocal/textos/regulamentos/BRA&#95;648.pdf . Accessed 21 Oct 2020.
ATSDR: Agency for Toxic Substances and Disease Registry (2019) ATSDR’s substance priority list. https://www.atsdr.cdc.gov/spl/index.html#2019spl . Accessed 20 April 2021.
Batista BL, Rodrigues JL, Nunes JA, Souza VC, Barbosa F Jr (2009) Exploiting dynamic reaction cell inductively coupled plasma mass spectrometry (DRC-ICP-MS) for sequential determination of trace elements in blood using a dilute-and-shoot procedure. Anal Chim Acta 639(1-2):13–18. https://doi.org/10.1016/j.aca.2009.03.016. (PMID: 10.1016/j.aca.2009.03.016)
Batista BL, Rodrigues JL, Tormen L, Curtius AJ, Barbosa F (2009) Reference concentrations for trace elements in urine for the brazilian population based on q-ICP-MS with a simple dilute-and-shoot procedure. J Braz Chem Soc 20(8):1406–1413. https://doi.org/10.1590/S0103-50532009000800004. (PMID: 10.1590/S0103-50532009000800004)
Bulka CM, Daviglus ML, Persky VW, Durazo-Arvizu RA, Lash JP, Elfassy T, Lee DJ, Ramos AR, Tarraf W, Argos M (2019) Association of occupational exposures with cardiovascular disease among US Hispanics/Latinos. Heart. 105(6):439–448. https://doi.org/10.1136/heartjnl-2018-313463. (PMID: 10.1136/heartjnl-2018-313463)
Buschinelli JTP (2020) Toxicologia Ocupacional. Fundacentro, São Paulo.
Carneiro FF (2015) Dossiê ABRASCO: um alerta sobre os impactos dos agrotóxicos na saúde: EPSJV/Expressão Popular.
Cederbaum AI (2012) Alcohol metabolism. Clin Liver Dis 16(4):667–685. https://doi.org/10.1016/j.cld.2012.08.002. (PMID: 10.1016/j.cld.2012.08.002)
Cestonaro LV, Garcia SC, Nascimento S, Gauer B, Sauer E, Göethel G, Peruzzi C, Nardi J, Fão N, Piton Y, Braga W, Rocha R, Saint’Pierre T, Gioda A, Arbo MD (2020) Biochemical, hematological and immunological parameters and relationship with occupational exposure to pesticides and metals. Environ Sci Pollut Res Int 27(23):29291–29302. https://doi.org/10.1007/s11356-020-09203-3. (PMID: 10.1007/s11356-020-09203-3)
Chen L, Qu G, Sun X, Zhang S, Wang L, Sang N, du Y, Liu J, Liu S (2013) Characterization of the interaction between cadmium and chlorpyrifos with integrative techniques in incurring synergistic hepatoxicity. PLoS One 8(3):e59553. https://doi.org/10.1371/journal.pone.0059553. (PMID: 10.1371/journal.pone.0059553)
Colosio C, Alegakis AK, Tsatsakis AM (2013) Emerging health issues from chronic pesticide exposure: innovative methodologies and effects on molecular cell and tissue level. Toxicology. 307:1–2. https://doi.org/10.1016/j.tox.2013.04.006. (PMID: 10.1016/j.tox.2013.04.006)
DATASUS: Departamento de Informática do Sistema Único de Saúde (2019) Intoxicação Exógena – Notificações registradas no SINAN NET – Brasil. https://datasus.saude.gov.br/informacoes-de-saude-tabnet/ . Accessed 21 Oct 2020.
Flora SJ (2016) Arsenic and dichlorvos: possible interaction between two environmental contaminants. J Trace Elem Med Biol 35:43–60. https://doi.org/10.1016/j.jtemb.2016.01.012. (PMID: 10.1016/j.jtemb.2016.01.012)
Freire BM, Lange CN, Pedron T, Monteiro LR, Sanches LR, Dos Reis Pedreira-Filho W et al (2020) Occupational exposure of foundry workers assessed by the urinary concentrations of 18 elements and arsenic species. J Trace Elem Med Biol 62:126593. https://doi.org/10.1016/j.jtemb.2020.126593. (PMID: 10.1016/j.jtemb.2020.126593)
Ghazali AR, Abdul Razak NE, Othman MS, Othman H, Ishak I, Lubis SH, Mohammad N, Abd Hamid Z, Harun Z, Kamarulzaman F, Abdullah R (2012) Study of heavy metal levels among farmers of Muda Agricultural Development Authority, Malaysia. J Environ Public Health 2012:758349–758344. https://doi.org/10.1155/2012/758349. (PMID: 10.1155/2012/758349)
Gimeno-García E, Andreu V, Boluda R (1996) Heavy metals incidence in the application of inorganic fertilizers and pesticides to rice farming soils. Environ Pollut 92(1):19–25. https://doi.org/10.1016/0269-7491(95)00090-9. (PMID: 10.1016/0269-7491(95)00090-9)
Gunier RB, Bradman A, Jerrett M, Smith DR, Harley KG, Austin C, Vedar M, Arora M, Eskenazi B (2013) Determinants of manganese in prenatal dentin of shed teeth from CHAMACOS children living in an agricultural community. Environ Sci Technol 47(19):11249–11257. https://doi.org/10.1021/es4018688. (PMID: 10.1021/es4018688)
He W, Guo W, Qian Y, Zhang S, Ren D, Liu S (2015) Synergistic hepatotoxicity by cadmium and chlorpyrifos: disordered hepatic lipid homeostasis. Mol Med Rep 12(1):303–308. https://doi.org/10.3892/mmr.2015.3381. (PMID: 10.3892/mmr.2015.3381)
Hernández AF, Parrón T, Tsatsakis AM, Requena M, Alarcón R, López-Guarnido O (2013) Toxic effects of pesticide mixtures at a molecular level: their relevance to human health. Toxicology. 307:136–145. (PMID: 10.1016/j.tox.2012.06.009)
IBAMA: Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis (2019) Relatórios de comercialização de agrotóxicos/ Boletins anuais/ Boletim de 2019. https://www.ibama.gov.br/agrotoxicos/relatorios-de-comercializacao-de-agrotoxicos . Accessed 20 Oct 2020.
IBGE: Instituto Brasileiro de Geografia e Estatística (2020) Cidades e Estados: Marialva-PR. https://www.ibge.gov.br/cidades-e-estados/pr/marialva.html . Accessed 20 Oct 2020.
Jacobsen PR, Christiansen S, Boberg J, Nellemann C, Hass U (2010) Combined exposure to endocrine disrupting pesticides impairs parturition, causes pup mortality and affects sexual differentiation in rats. Int J Androl 33(2):434–442. https://doi.org/10.1111/j.1365-2605.2009.01046.x. (PMID: 10.1111/j.1365-2605.2009.01046.x)
Jayasumana C, Gunatilake S, Siribaddana S (2015) Simultaneous exposure to multiple heavy metals and glyphosate may contribute to Sri Lankan agricultural nephropathy. BMC Nephrol 16:103. https://doi.org/10.1186/s12882-015-0109-. (PMID: 10.1186/s12882-015-0109-)
Kennedy MC, van der Voet H, Roelofs VJ, Roelofs W, Glass CR, de Boer WJ, Kruisselbrink JW, Hart ADM (2015) New approaches to uncertainty analysis for use in aggregate and cumulative risk assessment of pesticides. Food Chem Toxicol 79:54–64. https://doi.org/10.1016/j.fct.2015.02.008. (PMID: 10.1016/j.fct.2015.02.008)
Li X, Dong S, Su X (2018) Copper and other heavy metals in grapes: a pilot study tracing influential factors and evaluating potential risks in China. Sci Rep 8(1):17407. https://doi.org/10.1038/s41598-018-34767-z. (PMID: 10.1038/s41598-018-34767-z)
López-Gálvez N, Wagoner R, Quirós-Alcalá L, Van Horne YO, Furlong M, Avila E, Beamer P (2019) Systematic literature review of the take-home route of pesticide exposure via biomonitoring and environmental monitoring. Int J Environ Res Public Health 16(12):2177. https://doi.org/10.3390/ijerph16122177. (PMID: 10.3390/ijerph16122177)
Mora AM, van Wendel de Joode B, Mergler D, Cordoba L, Cano C, Quesada R et al (2014) Blood and hair manganese concentrations in pregnant women from the infants’ environmental health study (ISA) in Costa Rica. Environ Sci Technol 48(6):3467–3476. https://doi.org/10.1021/es404279r. (PMID: 10.1021/es404279r)
MTE. Ministério do Trabalho e Emprego, 1978 (2020) Norma regulamentadora NR 7 - Programa de controle médico de saúde ocupacional. Publicada na Portaria SEPRT n.° 6.734, de 10 de março de 2020. https://enit.trabalho.gov.br/portal/images/Arquivos&#95;SST/SST&#95;NR/NR-07.pdf . Accessed 20 Oct 2020.
Nicolopoulou-Stamati P, Maipas S, Kotampasi C, Stamatis P, Hens L (2016) Chemical pesticides and human health: the urgent need for a new concept in agriculture. Front Public Health 4:148. https://doi.org/10.3389/fpubh.2016.00148. (PMID: 10.3389/fpubh.2016.00148)
Nordberg GF (2010) Biomarkers of exposure, effects and susceptibility in humans and their application in studies of interactions among metals in China. Toxicol Lett 192(1):45–49. https://doi.org/10.1016/j.toxlet.2009.06.859. (PMID: 10.1016/j.toxlet.2009.06.859)
Nordberg G, Fowler B, Nordberg M (2014) Handbook on the toxicology of metals, 4th edn. Elsevier.
Ratner MH, Farb DH, Ozer J, Feldman RG, Durso R (2014) Younger age at onset of sporadic Parkinson’s disease among subjects occupationally exposed to metals and pesticides. Interdiscip Toxicol 7(3):123–133. https://doi.org/10.2478/intox-2014-0017. (PMID: 10.2478/intox-2014-0017)
Rehman H, Aziz AT, Saggu S, VanWert AL, Zidan N (2017) Additive toxic effect of deltamethrin and cadmium on hepatic, hematological, and immunological parameters in mice. Toxicol Ind Health 33(6):495–502. https://doi.org/10.1177/0748233716684710. (PMID: 10.1177/0748233716684710)
Rider CV, Furr JR, Wilson VS, Gray LE Jr (2010) Cumulative effects of in utero administration of mixtures of reproductive toxicants that disrupt common target tissues via diverse mechanisms of toxicity. Int J Androl 33(2):443–462. https://doi.org/10.1111/j.1365-2605.2009.01049.x. (PMID: 10.1111/j.1365-2605.2009.01049.x)
Rocha GH, Lini RS, Barbosa F Jr, Batista BL, de Oliveira Souza VC, Nerilo SB et al (2015) Exposure to heavy metals due to pesticide use by vineyard farmers. Int Arch Occup Environ Health 88(7):875–880. https://doi.org/10.1007/s00420-014-1010-1. (PMID: 10.1007/s00420-014-1010-1)
Rocha GH, Steinbach C, Munhoz JR, Madia MA, Faria JK, Hoeltgebaum D et al (2016) Trace metal levels in serum and urine of a population in southern Brazil. J Trace Elem Med Biol 35:61–65. https://doi.org/10.1016/j.jtemb.2015.12.005. (PMID: 10.1016/j.jtemb.2015.12.005)
Satarug S, Baker JR, Urbenjapol S, Haswell-Elkins M, Reilly PE, Williams DJ et al (2003) A global perspective on cadmium pollution and toxicity in non-occupationally exposed population. Toxicol Lett 137(1-2):65–83. https://doi.org/10.1016/s0378-4274(02)00381-8. (PMID: 10.1016/s0378-4274(02)00381-8)
SEAB: Secretaria de Estado da Agricultura e do Abastecimento. Departamento De Economia Rural (2018) Valor Bruto da Produção Agropecuária 2018. Governo do Estado do Paraná, Curitiba.
SESA: Secretaria de Estado da Saúde do Paraná, Superintendência de Vigilância em Saúde, Centro Estadual de Saúde do Trabalhador (2013) Protocolo de avaliação das intoxicações crônicas por agrotóxico crônicas por agrotóxico. Curitiba.
Sexton K (2012) Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors. Int J Environ Res Public Health 9(2):370–390. https://doi.org/10.3390/ijerph9020370. (PMID: 10.3390/ijerph9020370)
Sharma RK, Sharma B (2012) In-vitro carbofuran induced genotoxicity in human lymphocytes and its mitigation by vitamins C and E. Dis Markers 32:153–163. https://doi.org/10.3233/DMA-2011-0870. (PMID: 10.3233/DMA-2011-0870)
Sharma B, Singh S, Siddiqi NJ (2014) Biomedical implications of heavy metals induced imbalances in redox systems. Biomed Res Int 2014:1–26. https://doi.org/10.1155/2014/640754. (PMID: 10.1155/2014/640754)
Singh N, Gupta VK, Kumar A, Sharma B (2017) Synergistic effects of heavy metals and pesticides in living systems. Front Chem 5:70. https://doi.org/10.3389/fchem.2017.00070. (PMID: 10.3389/fchem.2017.00070)
Singh N, Kumar A, Gupta VK, Sharma B (2018) Biochemical and molecular bases of lead induced toxicity in mammalian systems and possible mitigations. Chem Res Toxicol 31:1009–1021. https://doi.org/10.1021/acs.chemrestox.8b00193. (PMID: 10.1021/acs.chemrestox.8b00193)
Sousa JA, de Oliveira FH, de Carvalho CM, Pereira CF, de Oliveira FS, da Silva SL (2016) Perception of rural producers regarding the use of pesticides. Rev Bras Agric Irrig 10(5):976–989. https://doi.org/10.7127/rbai.v10n500484.
Thompson T, Freestone D, Michalczyk AA, Ackland ML (2012) Copper levels in buccal cells of vineyard workers engaged in various activities. Ann Occup Hyg 56(3):305–314. https://doi.org/10.1093/annhyg/mer086. (PMID: 10.1093/annhyg/mer086)
Tsatsakis AM, Docea AO, Tsitsimpikou C (2016) New challenges in risk assessment of chemicals when simulating real exposure scenarios; simultaneous multi-chemicals’ low dose exposure. Food Chem Toxicol 96:174–176. https://doi.org/10.1016/j.fct.2016.08.011. (PMID: 10.1016/j.fct.2016.08.011)
Viana LS, Queiroz IFR, de Sales Filho RF, Ribeiro MA, Albuquerque IMAN, Neto FRGX (2017) Contextualizando a realidade do uso de agrotóxicos na agricultura familiar. Extensão Ação 1(13):54–68. https://doi.org/10.32356/exta.v1.n13.19708. (PMID: 10.32356/exta.v1.n13.19708)
Vinceti M, Bottecchi I, Fan A, Finkelstein Y, Mandrioli J (2012) Are environmental exposures to selenium, heavy metals, and pesticides risk factors for amyotrophic lateral sclerosis? Rev Environ Health 27(1):19–41. https://doi.org/10.1515/reveh-2012-0002. (PMID: 10.1515/reveh-2012-0002)
Wickerham EL, Lozoff B, Shao J, Kaciroti N, Xia Y, Meeker JD (2012) Reduced birth weight in relation to pesticide mixtures detected in cord blood of full-term infants. Environ Int 47:80–85. https://doi.org/10.1016/j.envint.2012.06.007. (PMID: 10.1016/j.envint.2012.06.007)
Xu MY, Wang P, Sun YJ, Yang L, Wu YJ (2017) Joint toxicity of chlorpyrifos and cadmium on the oxidative stress and mitochondrial damage in neuronal cells. Food Chem Toxicol 103:246–252. https://doi.org/10.1016/j.fct.2017.03.013. (PMID: 10.1016/j.fct.2017.03.013)
Yarpuz-Bozdogan N (2018) The importance of personal protective equipment in pesticide applications in agriculture. Curr Opin Environ Sci Health 4:1–4. https://doi.org/10.1016/j.coesh.2018.02.001. (PMID: 10.1016/j.coesh.2018.02.001)
معلومات مُعتمدة: 35591.433.38503.22082016 Secretaria de Ciência, Tecnologia e Ensino Superior, Governo do Estado de Parana (BR); 001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
فهرسة مساهمة: Keywords: Farmers; Occupational exposure; Pesticides; Principal component analysis; Trace elements; Viticulture
المشرفين على المادة: 0 (Pesticides)
0 (Trace Elements)
تواريخ الأحداث: Date Created: 20210515 Date Completed: 20210924 Latest Revision: 20210924
رمز التحديث: 20240628
DOI: 10.1007/s11356-021-14384-6
PMID: 33991300
قاعدة البيانات: MEDLINE
الوصف
تدمد:1614-7499
DOI:10.1007/s11356-021-14384-6