دورية أكاديمية
Investigation of dopaminergic signalling in Meis homeobox 1 (Meis1) deficient mice as an animal model of restless legs syndrome.
| العنوان: | Investigation of dopaminergic signalling in Meis homeobox 1 (Meis1) deficient mice as an animal model of restless legs syndrome. |
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| المؤلفون: | Cathiard L; Institute of Genetics and Molecular and Cellular Biology, CNRS UMR7104, INSERM U1258, University of Strasbourg, Illkirch, France., Fraulob V; Institute of Genetics and Molecular and Cellular Biology, CNRS UMR7104, INSERM U1258, University of Strasbourg, Illkirch, France., Lam DD; Institute for Human Genetic, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Torres M; Cardiovascular Development Program, Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain., Winkelmann J; Institute for Human Genetic, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.; Chair for Neucgenetic, Klinikum rechts der Isar, Technische Universität München; Institute for Neurogenomics, Helmholtz Zentrum München; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Krężel W; Institute of Genetics and Molecular and Cellular Biology, CNRS UMR7104, INSERM U1258, University of Strasbourg, Illkirch, France. |
| المصدر: | Journal of sleep research [J Sleep Res] 2021 Oct; Vol. 30 (5), pp. e13311. Date of Electronic Publication: 2021 May 18. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published on behalf of the European Sleep Research Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9214441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2869 (Electronic) Linking ISSN: 09621105 NLM ISO Abbreviation: J Sleep Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford ; Boston : Published on behalf of the European Sleep Research Society by Blackwell Scientific Publications, c1992- |
| مواضيع طبية MeSH: | Restless Legs Syndrome*/genetics, Animals ; Disease Models, Animal ; Dopamine ; Genes, Homeobox ; Mice ; Myeloid Ecotropic Viral Integration Site 1 Protein/genetics |
| مستخلص: | Restless legs syndrome (RLS) is a common neurological disorder in which sensorimotor symptoms lead to sleep disturbances with substantial impact on life quality. RLS is caused by a combination of genetic and environmental factors, and Meis homeobox 1 (MEIS1) was identified as the main genetic risk factor. The efficacy of dopaminergic agonists, including dopamine D (© 2021 European Sleep Research Society.) |
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| فهرسة مساهمة: | Keywords: animal behaviour; basal ganglia; genetic mouse models; hyperactivity; motor disorders; sex differences |
| المشرفين على المادة: | 0 (Meis1 protein, mouse) 0 (Myeloid Ecotropic Viral Integration Site 1 Protein) VTD58H1Z2X (Dopamine) |
| تواريخ الأحداث: | Date Created: 20210519 Date Completed: 20211021 Latest Revision: 20220531 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1111/jsr.13311 |
| PMID: | 34008292 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1365-2869 |
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| DOI: | 10.1111/jsr.13311 |