دورية أكاديمية

The PIDDosome: centrosome guardian and backup on the DNA damage response.

التفاصيل البيبلوغرافية
العنوان: The PIDDosome: centrosome guardian and backup on the DNA damage response.
المؤلفون: Burigotto M; Armenise-Harvard Laboratory of Cell Division, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy., Fava LL; Armenise-Harvard Laboratory of Cell Division, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.
المصدر: Molecular & cellular oncology [Mol Cell Oncol] 2021 Mar 28; Vol. 8 (3), pp. 1893625. Date of Electronic Publication: 2021 Mar 28 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101642411 Publication Model: eCollection Cited Medium: Print ISSN: 2372-3556 (Print) Linking ISSN: 23723556 NLM ISO Abbreviation: Mol Cell Oncol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Philadelphia, PA : Taylor & Francis, [2014]-
مستخلص: The PIDDosome is a Caspase-2-activating platform assembling in response to centrosome amplification or genotoxic stress. We have recently shown that both stimuli depend on ANKRD26 (ankyrin repeat domain-containing protein 26)-mediated localization of PIDD1 (p53-inducible protein with death domain) at the centrosome, demonstrating how this organelle can directly influence cell fate.
(© 2021 Taylor & Francis Group, LLC.)
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فهرسة مساهمة: Keywords: DNA damage; PIDDosome; centrosome; p53
تواريخ الأحداث: Date Created: 20210524 Latest Revision: 20220329
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8128191
DOI: 10.1080/23723556.2021.1893625
PMID: 34027036
قاعدة البيانات: MEDLINE
الوصف
تدمد:2372-3556
DOI:10.1080/23723556.2021.1893625