دورية أكاديمية
Oligometastatic Parathyroid Carcinoma Presenting as Neck Pain: A Case Report.
| العنوان: | Oligometastatic Parathyroid Carcinoma Presenting as Neck Pain: A Case Report. |
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| المؤلفون: | Yu KM; Department of Otorhinolaryngology-Head & Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Trimble DJ; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Conner CR; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Sheinberg DL; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Low GMI; Department of Otorhinolaryngology-Head & Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Saluja K; Department of Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Schmitt KM; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Karni RJ; Department of Otorhinolaryngology-Head & Neck Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA. |
| المصدر: | Ear, nose, & throat journal [Ear Nose Throat J] 2023 Oct; Vol. 102 (10), pp. 635-639. Date of Electronic Publication: 2021 May 27. |
| نوع المنشور: | Case Reports; Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 7701817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7522 (Electronic) Linking ISSN: 01455613 NLM ISO Abbreviation: Ear Nose Throat J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Thousand Oaks, CA : SAGE Publications Original Publication: [New York, Insight Pub. Co.] |
| مواضيع طبية MeSH: | Parathyroid Neoplasms*/complications , Parathyroid Neoplasms*/diagnosis , Parathyroid Neoplasms*/pathology , Carcinoma*/pathology, Humans ; Female ; Middle Aged ; Neck Pain/etiology ; Neck/pathology ; Parathyroid Hormone |
| مستخلص: | Background: Parathyroid carcinoma (PC) is an exceedingly rare, slow-growing but progressive endocrine malignancy that represents a diagnostic and therapeutic challenge. Vertebral metastasis of PC is remarkable, with only 3 prior cases of spinal metastasis reported in the literature. Case Description: A 62-year-old woman presented with 1 week of neck pain radiating down her right arm. Cervical x-ray revealed a lytic lesion of the C4 vertebral body. Lab work revealed hypercalcemia with an elevated parathyroid hormone level. Computed tomography and magnetic resonance imaging revealed frank destruction of the C4 vertebral body and pedicles by PC. She was treated with corpectomy, mass excision, anterior cervical discectomy and fusion, postoperative radiotherapy, and nonspecific inhibitors of active tumor pathways. Her symptoms resolved postoperatively, and she has remained negative for reoccurrence at 15-month follow-up. Conclusions: To the authors' knowledge, we report the first described cervical spine metastasis of PC. Additionally, we review the treatment of this rare neoplasm in an extremely rare location in the age of tumor sequencing and morphoproteomic analysis. |
| فهرسة مساهمة: | Keywords: atypical parathyroid neoplasm; cervical spine; metastasis; parathyroid carcinoma; primary hyperparathyroidism |
| المشرفين على المادة: | 0 (Parathyroid Hormone) |
| تواريخ الأحداث: | Date Created: 20210527 Date Completed: 20230927 Latest Revision: 20230927 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/01455613211016703 |
| PMID: | 34041944 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1942-7522 |
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| DOI: | 10.1177/01455613211016703 |