دورية أكاديمية
A global metagenomic map of urban microbiomes and antimicrobial resistance.
العنوان: | A global metagenomic map of urban microbiomes and antimicrobial resistance. |
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المؤلفون: | Danko D; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Bezdan D; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany; NGS Competence Center Tübingen (NCCT), University of Tübingen, Tübingen, Germany., Afshin EE; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Ahsanuddin S; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bhattacharya C; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Butler DJ; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Chng KR; Genome Institute of Singapore, A(∗)STAR, Singapore, Singapore., Donnellan D; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Hecht J; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain., Jackson K; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Kuchin K; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Karasikov M; ETH Zurich, Department of Computer Science, Biomedical Informatics Group, Zurich, Switzerland; University Hospital Zurich, Biomedical Informatics Research, Zurich, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lyons A; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Mak L; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Meleshko D; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Mustafa H; ETH Zurich, Department of Computer Science, Biomedical Informatics Group, Zurich, Switzerland; University Hospital Zurich, Biomedical Informatics Research, Zurich, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Mutai B; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain; Kenya Medical Research Institute - Kisumu, Kisumu, Kenya., Neches RY; Department of Energy, Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Ng A; Genome Institute of Singapore, A(∗)STAR, Singapore, Singapore., Nikolayeva O; Independent Researcher, Zurich, Switzerland., Nikolayeva T; Independent Researcher, Zurich, Switzerland., Png E; Genome Institute of Singapore, A(∗)STAR, Singapore, Singapore., Ryon KA; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Sanchez JL; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Shaaban H; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Sierra MA; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Thomas D; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Young B; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Abudayyeh OO; Massachusetts Institute of Technology, McGovern Institute for Brain Research, Cambridge, MA, USA., Alicea J; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Bhattacharyya M; Machine Intelligence Unit, Indian Statistical Institute, Kolkata, India; Centre for Artificial Intelligence and Machine Learning, Indian Statistical Institute, Kolkata, India., Blekhman R; University of Minnesota, Minneapolis, MN, USA., Castro-Nallar E; Universidad Andres Bello, Center for Bioinformatics and Integrative Biology, Facultad de Ciencias de la Vida, Santiago, Chile., Cañas AM; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Chatziefthimiou AD; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Crawford RW; California State University, Sacramento, Sacramento, CA, USA., De Filippis F; Department of Agricultural Sciences, Division of Microbiology, University of Naples Federico II, Naples, Italy; Task Force on Microbiome Studies, University of Naples Federico II, Naples, Italy., Deng Y; University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA., Desnues C; Aix-Marseille Université, Mediterranean Institute of Oceanology, Université de Toulon, CNRS, IRD, UM 110, Marseille, France., Dias-Neto E; Medical Genomics group, A.C.Camargo Cancer Center, São Paulo - SP, Brazil., Dybwad M; Norwegian Defence Research Establishment FFI, Kjeller, Norway., Elhaik E; Department of Biology, Lund University, Lund, Sweden., Ercolini D; Department of Agricultural Sciences, Division of Microbiology, University of Naples Federico II, Naples, Italy; Task Force on Microbiome Studies, University of Naples Federico II, Naples, Italy., Frolova A; Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine, Kyiv, Ukraine; Kyiv Academic University, Kyiv, Ukraine., Gankin D; Massachusetts Institute of Technology, McGovern Institute for Brain Research, Cambridge, MA, USA., Gootenberg JS; Massachusetts Institute of Technology, McGovern Institute for Brain Research, Cambridge, MA, USA., Graf AB; University of Applied Sciences Vienna, Vienna, Austria., Green DC; Department of Analytical, Environmental and Forensic Sciences, King's College London, London, UK., Hajirasouliha I; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Hastings JJA; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Hernandez M; University of Colorado at Boulder, Boulder, CO, USA., Iraola G; Microbial Genomics Laboratory, Institut Pasteur de Montevideo, Montevideo, Uruguay; Center for Integrative Biology, Universidad Mayor, Santiago de Chile, Santiago, Chile; Wellcome Sanger Institute, Hinxton, UK., Jang S; Institut Pasteur Korea, Seoul, South Korea., Kahles A; ETH Zurich, Department of Computer Science, Biomedical Informatics Group, Zurich, Switzerland; Kyiv Academic University, Kyiv, Ukraine; C+, Research Center in Technologies for Society, School of Engineering, Universidad del Desarrollo, Santiago, Chile., Kelly FJ; Department of Analytical, Environmental and Forensic Sciences, King's College London, London, UK., Knights K; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Kyrpides NC; Department of Energy, Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Łabaj PP; State Key Laboratory of Genetic Engineering (SKLGE) and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Human Phenome Institute, Fudan University, Shanghai, China; Małopolska Centre of Biotechnology, Jagiellonian University, Kraków, Poland; Boku University Viennna, Vienna, Austria., Lee PKH; School of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China., Leung MHY; School of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China., Ljungdahl PO; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden., Mason-Buck G; Department of Analytical, Environmental and Forensic Sciences, King's College London, London, UK., McGrath K; Microba, 388 Queen St, Brisbane City, QLD 4000, Australia., Meydan C; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Mongodin EF; University of Maryland School of Medicine, Institute for Genome Sciences, Baltimore, MD, USA., Moraes MO; Fundação Oswaldo Cruz, Rio de Janeiro - RJ, Brazil., Nagarajan N; Genome Institute of Singapore, A(∗)STAR, Singapore, Singapore., Nieto-Caballero M; University of Colorado at Boulder, Boulder, CO, USA., Noushmehr H; University of São Paulo, Ribeirão Preto Medical School, Ribeirão Preto - SP, Brazil., Oliveira M; Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal., Ossowski S; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany; NGS Competence Center Tübingen (NCCT), University of Tübingen, Tübingen, Germany., Osuolale OO; Applied Environmental Metagenomics and Infectious Diseases Research (AEMIDR), Department of Biological Sciences, Elizade University, Ilara-Mokin, Nigeria., Özcan O; Acibadem Mehmet Ali Aydınlar University, Istanbul, Turkey., Paez-Espino D; Department of Energy, Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Rascovan N; Microbial Paleogenomics Unit, Institut Pasteur, CNRS UMR2000, Paris 75015, France., Richard H; Sorbonne University, Faculty of Science, Institute of Biology Paris-Seine, Laboratory of Computational and Quantitative Biology, Paris, France; Robert Koch Institute, Berlin, Germany., Rätsch G; ETH Zurich, Department of Computer Science, Biomedical Informatics Group, Zurich, Switzerland; University Hospital Zurich, Biomedical Informatics Research, Zurich, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Schriml LM; University of Maryland School of Medicine, Institute for Genome Sciences, Baltimore, MD, USA., Semmler T; Robert Koch Institute, Berlin, Germany., Sezerman OU; Acibadem Mehmet Ali Aydınlar University, Istanbul, Turkey., Shi L; Center for Pharmacogenomics, School of Life Sciences and Shanghai Cancer Center, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering (SKLGE) and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Human Phenome Institute, Fudan University, Shanghai, China., Shi T; The Center for Bioinformatics and Computational Biology, Shanghai Key Laboratory of Regulatory Biology, the Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China., Siam R; University of Medicine and Health Sciences, St. Kitts, West Indies and American University in Cairo, Cairo, Egypt., Song LH; 108 Military Central Hospital, Hanoi, Vietnam; Vietnamese-German Center for Medical Research (VG-CARE), Hanoi, Vietnam., Suzuki H; Keio University, Tokyo, Japan., Court DS; Department of Analytical, Environmental and Forensic Sciences, King's College London, London, UK., Tighe SW; University of Vermont, Burlington, VT, USA., Tong X; School of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China., Udekwu KI; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden; SciLife EVP, Department of Aquatic Sciences Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden., Ugalde JA; Millennium Initiative for Collaborative Research on Bacterial Resistance, Santiago, Chile; C+, Research Center in Technologies for Society, School of Engineering, Universidad del Desarrollo, Santiago, Chile., Valentine B; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Vassilev DI; Faculty of Mathematics and Informatics, Sofia University 'St. Kliment Ohridski,' Sofia, Bulgaria., Vayndorf EM; Institute of Arctic Biology, University of Alaska, Fairbanks, Fairbanks, AK, USA., Velavan TP; Institute of Tropical Medicine, Univeristätsklinikum Tübingen, Tübingen, Germany; Faculty of Medicine, Duy Tan University, Da Nang, Vietnam., Wu J; The Center for Bioinformatics and Computational Biology, Shanghai Key Laboratory of Regulatory Biology, the Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China., Zambrano MM; Corporación Corpogen-Research Center, Bogotá, Colombia., Zhu J; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA., Zhu S; State Key Laboratory of Genetic Engineering (SKLGE) and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Human Phenome Institute, Fudan University, Shanghai, China; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China., Mason CE; Weill Cornell Medicine, New York, NY, USA; The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, NY, USA; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA. Electronic address: chm2042@med.cornell.edu. |
مؤلفون مشاركون: | International MetaSUB Consortium |
المصدر: | Cell [Cell] 2021 Jun 24; Vol. 184 (13), pp. 3376-3393.e17. Date of Electronic Publication: 2021 May 26. |
نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
اللغة: | English |
بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Cambridge, Ma : Cell Press Original Publication: Cambridge, MIT Press. |
مواضيع طبية MeSH: | Metagenomics* , Urban Population*, Drug Resistance, Bacterial/*genetics , Microbiota/*genetics, Biodiversity ; Databases, Genetic ; Humans |
مستخلص: | We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities. Competing Interests: Declaration of interests C.E.M. is co-founder of Biotia and Onegevity Health. D.B. is co-founder and CSO of Poppy Health Inc. The other authors declare they have no competing interests that impacted this study. (Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.) |
References: | BMC Res Notes. 2016 Feb 12;9:88. (PMID: 26868221) Microbiome. 2017 Mar 3;5(1):27. (PMID: 28253908) Cell Syst. 2015 Jul 29;1(1):72-87. (PMID: 26594662) Nucleic Acids Res. 2017 Jan 4;45(D1):D574-D580. (PMID: 27899569) Nature. 2017 Oct 5;550(7674):61-66. (PMID: 28953883) Genome Res. 2017 May;27(5):824-834. (PMID: 28298430) Bioinformatics. 2015 Nov 15;31(22):3718-20. (PMID: 26209431) Nat Med. 2019 Feb;25(2):206-211. (PMID: 30728537) Microbiome. 2016 Jun 03;4(1):24. (PMID: 27255532) Bioinformatics. 2015 Mar 15;31(6):926-32. (PMID: 25398609) Bioinformatics. 2011 Apr 15;27(8):1061-7. (PMID: 21317142) PeerJ. 2019 Jul 26;7:e7359. (PMID: 31388474) Gates Open Res. 2018 Jan 5;2:3. (PMID: 29630066) Nature. 2012 Jun 13;486(7402):207-14. (PMID: 22699609) Microbiome. 2019 Feb 28;7(1):35. (PMID: 30819245) Front Microbiol. 2016 Nov 01;7:1728. (PMID: 27847505) Infect Ecol Epidemiol. 2015 Jun 24;5:27060. (PMID: 26112265) Front Microbiol. 2019 May 16;10:982. (PMID: 31156569) Cell Rep. 2018 Jul 31;24(5):1190-1202.e5. (PMID: 30067975) Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12229-12234. (PMID: 30420511) Bioinformatics. 2007 May 15;23(10):1282-8. (PMID: 17379688) Nature. 2017 Nov 23;551(7681):457-463. (PMID: 29088705) Science. 2017 Sep 15;357(6356):1099-1100. (PMID: 28912233) Nat Med. 2020 Jun;26(6):941-951. (PMID: 32514171) ISME J. 2016 Mar;10(3):751-60. (PMID: 26394011) Genome Biol. 2004;5(2):R12. (PMID: 14759262) Nucleic Acids Res. 2019 Jan 8;47(D1):D678-D686. (PMID: 30407573) ISME J. 2009 Feb;3(2):243-51. (PMID: 18843302) Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3463-E3470. (PMID: 29581252) Allergy. 2005 Nov;60(11):1357-60. (PMID: 16197466) mSystems. 2016 Jun 28;1(3):. (PMID: 27822528) N Engl J Med. 2019 Jun 13;380(24):2327-2340. (PMID: 31189036) ISME J. 2017 Dec;11(12):2864-2868. (PMID: 28742071) Genome Biol. 2018 Nov 16;19(1):198. (PMID: 30445993) mBio. 2016 Apr 19;7(2):e02227-15. (PMID: 27094336) Nucleic Acids Res. 2018 Jul 2;46(W1):W246-W251. (PMID: 29790974) Nat Methods. 2020 Mar;17(3):261-272. (PMID: 32015543) Nature. 2016 Jul 21;535(7612):435-439. (PMID: 27409808) Nat Protoc. 2017 Aug;12(8):1673-1682. (PMID: 28749930) Essays Biochem. 2017 Mar 3;61(1):1-10. (PMID: 28258225) Lancet Microbe. 2021 Apr;2(4):e135-e136. (PMID: 33655229) Bioinformatics. 2017 Sep 1;33(17):2759-2761. (PMID: 28472236) Nat Rev Microbiol. 2018 Nov;16(11):661-670. (PMID: 30127345) Occup Environ Med. 1998 Sep;55(9):579-84. (PMID: 9861178) Nucleic Acids Res. 2019 Jul 2;47(W1):W256-W259. (PMID: 30931475) Sci Transl Med. 2017 May 24;9(391):. (PMID: 28539477) Nat Commun. 2019 Mar 8;10(1):1124. (PMID: 30850636) Nat Commun. 2017 Nov 27;8(1):1814. (PMID: 29180750) Nat Biotechnol. 2020 Sep;38(9):1079-1086. (PMID: 32341564) Nature. 2016 Aug 25;536(7617):425-30. (PMID: 27533034) Nature. 2018 Aug;560(7717):233-237. (PMID: 30069051) Genome Biol. 2017 Sep 21;18(1):182. (PMID: 28934964) Nat Methods. 2012 Mar 04;9(4):357-9. (PMID: 22388286) Microbiome. 2017 Sep 22;5(1):125. (PMID: 28938903) ISME J. 2018 Jun;12(6):1404-1413. (PMID: 29662146) Science. 2018 Jan 19;359(6373):320-325. (PMID: 29348236) Chronobiol Int. 2018 Apr;35(4):573-577. (PMID: 29341791) Science. 2008 Jul 18;321(5887):365-7. (PMID: 18635792) J Biomol Tech. 2017 Apr;28(1):40-45. (PMID: 28337072) Genome Res. 2015 Jul;25(7):1043-55. (PMID: 25977477) Nat Methods. 2015 Jan;12(1):59-60. (PMID: 25402007) PLoS One. 2013 Dec 11;8(12):e81862. (PMID: 24349140) Nat Methods. 2018 Nov;15(11):962-968. (PMID: 30377376) PLoS One. 2010 Mar 10;5(3):e9490. (PMID: 20224823) Cell. 2019 Jan 24;176(3):649-662.e20. (PMID: 30661755) Proc Natl Acad Sci U S A. 2015 May 5;112(18):5649-54. (PMID: 25792457) Nat Biotechnol. 2018 Jul 6;36(7):660. (PMID: 29979671) ISME J. 2019 Nov;13(11):2750-2763. (PMID: 31289345) Appl Environ Microbiol. 2014 Nov;80(21):6760-70. (PMID: 25172855) Bioinformatics. 2019 Nov 15;:. (PMID: 31730192) Nat Rev Genet. 2018 Jan;19(1):9-20. (PMID: 29129921) Nat Microbiol. 2018 Feb;3(2):253. (PMID: 29234139) Genome Biol. 2016 Jun 20;17(1):132. (PMID: 27323842) Nature. 2019 Apr;568(7753):505-510. (PMID: 30867587) Environ Sci Technol. 2017 Jun 6;51(11):5863-5864. (PMID: 28489349) Mayo Clin Proc. 2012 Feb;87(2):198-208. (PMID: 22305032) mSystems. 2019 Aug 6;4(4):. (PMID: 31387933) J Mol Biol. 1990 Oct 5;215(3):403-10. (PMID: 2231712) |
معلومات مُعتمدة: | U01 DA053941 United States DA NIDA NIH HHS; T32 GM083937 United States GM NIGMS NIH HHS; MR/S019669/1 United Kingdom MRC_ Medical Research Council; UL1 TR000457 United States TR NCATS NIH HHS; R25 EB020393 United States EB NIBIB NIH HHS; R01 AI151059 United States AI NIAID NIH HHS; R21 AI129851 United States AI NIAID NIH HHS; R35 GM138152 United States GM NIGMS NIH HHS |
فهرسة مساهمة: | Investigator: N Abdullah; M Abraao; AH Adel; M Afaq; FS Al-Quaddoomi; I Alam; GE Albuquerque; A Alexiev; K Ali; LE Alvarado-Arnez; S Aly; J Amachee; MG Amorim; M Ampadu; MA Amran; N An; W Andrew; H Andrianjakarivony; M Angelov; V Antelo; C Aquino; Á Aranguren; LF Araujo; HF Vasquez Arevalo; J Arevalo; C Arnan; LE Alvarado Arnez; F Arredondo; M Arthur; F Asenjo; TS Aung; J Auvinet; N Aventin; S Ayaz; S Baburyan; AM Bakere; K Bakhl; TF Bartelli; E Batdelger; F Baudon; K Becher; C Bello; M Benchouaia; H Benisty; AS Benoiston; J Benson; D Benítez; J Bernardes; D Bertrand; S Beurmann; T Bitard-Feildel; L Bittner; C Black; G Blanc; B Blyther; T Bode; J Boeri; B Boldgiv; K Bolzli; A Bordigoni; C Borrelli; S Bouchard; JP Bouly; A Boyd; GP Branco; A Breschi; B Brindefalk; C Brion; A Briones; P Buczansla; CM Burke; A Burrell; A Butova; I Buttar; J Bynoe; S Bönigk; KO Bøifot; H Caballero; XW Cai; D Calderon; A Cantillo; M Carbajo; A Carbone; A Cardenas; K Carrillo; L Casalot; S Castro; AV Castro; A Castro; AVB Castro; S Cawthorne; J Cedillo; S Chaker; J Chalangal; A Chan; AI Chasapi; S Chatziefthimiou; SR Chaudhuri; AK Chavan; F Chavez; G Chem; X Chen; M Chen; JW Chen; A Chernomoretz; A Chettouh; D Cheung; D Chicas; S Chiu; H Choudhry; C Chrispin; K Ciaramella; E Cifuentes; J Cohen; DA Coil; S Collin; C Conger; R Conte; F Corsi; CN Cossio; AF Costa; D Cuebas; B D'Alessandro; KE Dahlhausen; AE Darling; P Das; LB Davenport; L David; NR Davidson; G Dayama; S Delmas; CK Deng; C Dequeker; A Desert; M Devi; FS Dezem; CN Dias; TR Donahoe; S Dorado; L Dorsey; V Dotsenko; S Du; A Dutan; N Eady; JA Eisen; M Elaskandrany; L Epping; JP Escalera-Antezana; CL Ettinger; I Faiz; L Fan; N Farhat; E Faure; F Fauzi; C Feigin; S Felice; LP Ferreira; G Figueroa; A Fleiss; D Flores; JL Velasco Flores; MAS Fonseca; J Foox; JC Forero; A Francis; K French; P Fresia; J Friedman; JJ Fuentes; J Galipon; M Garcia; L Garcia; C García; A Geiger; SM Gerner; SL Ghose; DP Giang; M Giménez; D Giovannelli; D Githae; S Gkotzis; L Godoy; S Goldman; GH Gonnet; J Gonzalez; A Gonzalez; C Gonzalez-Poblete; A Gray; T Gregory; C Greselle; S Guasco; J Guerra; N Gurianova; W Haehr; S Halary; F Hartkopf; JJA Hastings; A Hawkins-Zafarnia; NH Hazrin-Chong; E Helfrich; E Hell; T Henry; S Hernandez; PL Hernandez; D Hess-Homeier; LE Hittle; NX Hoan; A Holik; C Homma; I Hoxie; M Huber; E Humphries; S Hyland; A Hässig; R Häusler; N Hüsser; RA Petit; B Iderzorig; M Igarashi; SB Iqbal; S Ishikawa; S Ishizuka; S Islam; R Islam; K Ito; S Ito; T Ito; T Ivankovic; T Iwashiro; S Jackson; J Jacobs; M James; M Jaubert; ML Jerier; E Jiminez; A Jinfessa; Y De Jong; HW Joo; G Jospin; T Kajita; AS Ahmad Kassim; N Kato; A Kaur; I Kaur; F de Souza Gomes Kehdy; VS Khadka; S Khan; M Khavari; M Ki; G Kim; HJ Kim; S Kim; RJ King; K Knights; G KoLoMonaco; E Koag; N Kobko-Litskevitch; M Korshevniuk; M Kozhar; J Krebs; N Kubota; A Kuklin; SS Kumar; R Kwong; L Kwong; I Lafontaine; J Lago; TY Lai; E Laine; M Laiola; O Lakhneko; I Lamba; G de Lamotte; R Lannes; E De Lazzari; M Leahy; H Lee; Y Lee; L Lee; V Lemaire; E Leong; MHY Leung; D Lewandowska; C Li; W Liang; M Lin; P Lisboa; A Litskevitch; EM Liu; T Liu; MA Livia; YH Lo; S Losim; M Loubens; J Lu; O Lykhenko; S Lysakova; S Mahmoud; SA Majid; N Makogon; D Maldonado; K Mallari; TM Malta; M Mamun; D Manoir; G Marchandon; N Marciniak; S Marinovic; B Marques; N Mathews; Y Matsuzaki; V Matthys; M May; E McComb; A Meagher; A Melamed; W Menary; KN Mendez; A Mendez; IM Mendy; I Meng; A Menon; M Menor; R Meoded; N Merino; C Meydan; K Miah; M Mignotte; T Miketic; W Miranda; A Mitsios; R Miura; K Miyake; MD Moccia; N Mohan; M Mohsin; K Moitra; M Moldes; L Molina; J Molinet; OE Molomjamts; E Moniruzzaman; S Moon; I de Oliveira Moraes; M Moreno; MS Mosella; JW Moser; C Mozsary; AL Muehlbauer; O Muner; M Munia; N Munim; M Muscat; T Mustac; C Muñoz; F Nadalin; A Naeem; D Nagy-Szakal; M Nakagawa; A Narce; M Nasu; IG Navarrete; H Naveed; B Nazario; NR Nedunuri; T Neff; A Nesimi; WC Ng; S Ng; G Nguyen; E Ngwa; A Nicolas; P Nicolas; A Nika; H Noorzi; A Nosrati; H Noushmehr; DN Nunes; K O'Brien; NB O'Hara; G Oken; RA Olawoyin; JQ Oliete; K Olmeda; T Oluwadare; IA Oluwadare; N Ordioni; J Orpilla; J Orrego; M Ortega; P Osma; IO Osuolale; OM Osuolale; M Ota; F Oteri; Y Oto; R Ounit; CA Ouzounis; S Pakrashi; R Paras; C Pardo-Este; YJ Park; P Pastuszek; S Patel; J Pathmanathan; A Patrignani; M Perez; A Peros; S Persaud; A Peters; A Phillips; L Pineda; MP Pizzi; A Plaku; A Plaku; B Pompa-Hogan; MG Portilla; L Posada; M Priestman; B Prithiviraj; S Priya; P Pugdeethosal; CE Pugh; B Pulatov; A Pupiec; K Pyrshev; T Qing; S Rahiel; S Rahmatulloev; K Rajendran; A Ramcharan; A Ramirez-Rojas; S Rana; P Ratnanandan; TD Read; H Rehrauer; R Richer; A Rivera; M Rivera; A Robertiello; C Robinson; P Rodríguez; NA Rojas; P Roldán; A Rosario; S Roth; M Ruiz; SE Boja Ruiz; K Russell; M Rybak; TS Sabedot; M Sabina; I Saito; Y Saito; GA Malca Salas; C Salazar; KM San; J Sanchez; K Sanchir; R Sankar; PT de Souza Santos; Z Saravi; K Sasaki; Y Sato; M Sato; S Sato; R Sato; K Sato; N Sayara; S Schaaf; O Schacher; AM Schinke; R Schlapbach; C Schori; JR Schriml; F Segato; F Sepulveda; MS Serpa; PF De Sessions; JC Severyn; H Shaaban; M Shakil; S Shalaby; A Shari; H Shim; H Shirahata; Y Shiwa; R Siam; O Da Silva; JM Silva; G Simon; SK Singh; K Sluzek; R Smith; E So; N Andreu Somavilla; Y Sonohara; N Rufino de Sousa; C Souza; J Sperry; N Sprinsky; SG Stark; A La Storia; K Suganuma; H Suliman; J Sullivan; AAM Supie; C Suzuki; S Takagi; F Takahara; N Takahashi; K Takahashi; T Takeda; IK Takenaka; S Tanaka; A Tang; Y Man Tang; E Tarcitano; A Tassinari; M Taye; A Terrero; E Thambiraja; A Thiébaut; S Thomas; AM Thomas; Y Togashi; T Togashi; A Tomaselli; M Tomita; I Tomita; X Tong; O Toth; NC Toussaint; JM Tran; C Truong; SI Tsonev; K Tsuda; T Tsurumaki; M Tuz; Y Tymoshenko; C Urgiles; M Usui; S Vacant; B Valentine; LE Vann; F Velter; V Ventorino; P Vera-Wolf; R Vicedomini; MA Suarez-Villamil; S Vincent; R Vivancos-Koopman; A Wan; C Wang; T Warashina; A Watanabe; S Weekes; J Werner; D Westfall; LH Wieler; M Williams; SA Wolf; B Wong; YL Wong; T Wong; R Wright; T Wunderlin; R Yamanaka; J Yang; H Yano; GC Yeh; O Yemets; T Yeskova; S Yoshikawa; L Zafar; Y Zhang; S Zhang; A Zhang; Y Zheng; S Zubenko Keywords: AMR; BGC; NGS; antimicrobial resistance; built Environment; de novo assembly; global health; metagenome; microbiome; shotgun sequencing |
تواريخ الأحداث: | Date Created: 20210527 Date Completed: 20220105 Latest Revision: 20240505 |
رمز التحديث: | 20240505 |
مُعرف محوري في PubMed: | PMC8238498 |
DOI: | 10.1016/j.cell.2021.05.002 |
PMID: | 34043940 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1097-4172 |
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DOI: | 10.1016/j.cell.2021.05.002 |