دورية أكاديمية
Balancing Quality, Cost, and Access During Delivery of Newer Cellular and Immunotherapy Treatments.
العنوان: | Balancing Quality, Cost, and Access During Delivery of Newer Cellular and Immunotherapy Treatments. |
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المؤلفون: | Geethakumari PR; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 2201 Inwood Road, Dallas, TX, 76034, USA., Ramasamy DP; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 2201 Inwood Road, Dallas, TX, 76034, USA., Dholaria B; Vanderbilt University Medical Center, Nashville, TN, USA., Berdeja J; Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN, USA., Kansagra A; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 2201 Inwood Road, Dallas, TX, 76034, USA. ankit.kansagra@utsouthwestern.edu. |
المصدر: | Current hematologic malignancy reports [Curr Hematol Malig Rep] 2021 Aug; Vol. 16 (4), pp. 345-356. Date of Electronic Publication: 2021 Jun 05. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Current Science Country of Publication: United States NLM ID: 101262565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-822X (Electronic) Linking ISSN: 15588211 NLM ISO Abbreviation: Curr Hematol Malig Rep Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Philadelphia, Pa. : Current Science, c2006- |
مواضيع طبية MeSH: | Drug Delivery Systems/*methods , Immunotherapy/*methods , Neoplasms/*economics , Neoplasms/*therapy, Humans |
مستخلص: | Purpose of Review: The chimeric antigen receptor (CAR) T-cell therapy is currently changing the landscape of hematologic malignancies with multiple FDA-approved cell therapy products in the USA. The current administration process of the CAR T-cell therapy is complicated, labor-intensive, and expensive. Recent Findings: The chimeric antigen receptor (CAR) T-cell therapy is currently changing the landscape of hematologic malignancies with multiple FDA-approved cell therapy products in the USA. The current administration process of the CAR T-cell therapy is complicated, labor-intensive, and expensive. This review article addresses the present-day challenges and discusses opportunities to optimize the access and affordability of the CAR T-cell therapy. The field of cellular immunotherapy is going to change the future of solid tumors and non-oncological diseases. However, this promising therapy poses challenges in the administration and management of quality in the current field of healthcare. We describe various novel approaches to manage challenges in improving access and improving widescale implementation of cellular therapies. (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
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فهرسة مساهمة: | Keywords: Access; Acute lymphoblastic leukemia; Barriers; CAR T cell therapy; Cost-effectiveness; Immune-effector cell therapy; Immunotherapy; Lymphoma; Multiple myeloma; Quality |
تواريخ الأحداث: | Date Created: 20210605 Date Completed: 20210830 Latest Revision: 20230917 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC8179081 |
DOI: | 10.1007/s11899-021-00635-3 |
PMID: | 34089485 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1558-822X |
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DOI: | 10.1007/s11899-021-00635-3 |