دورية أكاديمية

The Burden of Adverse Neonatal Outcome among Antenatal Substance Users in Ethiopia: A Systematic Review and Meta-Analysis.

التفاصيل البيبلوغرافية
العنوان: The Burden of Adverse Neonatal Outcome among Antenatal Substance Users in Ethiopia: A Systematic Review and Meta-Analysis.
المؤلفون: Bayih WA; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Maternity and Neonatal Health Nursing., Ayalew MY; Bahir Dar University, Bahir Dar, Ethiopia.; Bachelor of Science degree in Comprehensive Nursing., Tadege M; Debre Tabor University, Debre Tabor, Ethiopia.; Assistant Professor of Human Nutrition., Mekie M; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Public Health degree in Reproductive Health., Kiros T; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Medical Micro-Biology., Alemu EM; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Public Health degree in Reproductive Health., Alemnew EF; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Advanced Clinical Anesthesia., Getacher L; Debre Berhan University, Debre Berhan, Ethiopia.; Master of Public Health degree in Human Nutrition., Belay DM; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Pediatrics and Child Health Nursing., Birhane BM; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Maternity and Neonatal Health Nursing., Alemu DKD; Debre Tabor University, Debre Tabor, Ethiopia.; Assistant Professor of General Human Surgery., Yitbarek GY; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Medical Physiology., Kefale B; Debre Tabor University, Debre Tabor, Ethiopia.; Master of Science degree in Clinical Pharmacy.
المصدر: Global pediatric health [Glob Pediatr Health] 2021 May 26; Vol. 8, pp. 2333794X211019699. Date of Electronic Publication: 2021 May 26 (Print Publication: 2021).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Sage Country of Publication: United States NLM ID: 101670224 Publication Model: eCollection Cited Medium: Internet ISSN: 2333-794X (Electronic) Linking ISSN: 2333794X NLM ISO Abbreviation: Glob Pediatr Health Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Thousand Oaks, CA] : Sage, [2014]-
مستخلص: Background. Substances mainly khat, alcohol and cigarette are used during pregnancy in Ethiopia. However, to this date, there is no pooled evidence about the burden of adverse neonatal outcomes among the substance users during pregnancy in the country. Methods . Eligible primary studies were accessed from 4 international data bases (Google Scholar, Science Direct, Scopus, and PubMed). The required data were extracted from these studies and then exported to stata version 14 for analysis. Subgroup analyses were conducted for evidence of heterogeneity. Results . A total of 2298 neonates were included from 7 studies. Among these neonates, 530(23.06%) were those whose mothers used substance during pregnancy (exposed group) whereas 1768 neonates were those whose mothers didn't use substance during pregnancy (controls group). The pooled prevalence of adverse neonatal outcome among the exposed mothers was 38.32% (95% CI: 29.48%, 47.16%; I 2  = 76.3%) whereas it was 16.29% (95% CI: 9.45%, 23.13%) among the controls. Adverse neonatal outcome was most burdensome among cigarette smokers 45.20% (95% CI: 37.68%, 52.73%; I 2  = .00%) when compared with khat chewers 34.00% (95% CI: 20.87%, 47.13%) and alcohol drinkers 38.47% (95% CI: 17.96%, 58.98%). Low birth weight 42.00% (95% CI: 18.01%, 65.99%; I 2  = 91.8%) was the most common adverse birth outcome. Conclusion . It was found that adverse neonatal outcomes were much more burdensome among antenatal substance users than the controls. Therefore, mothers should be enabled to quit using substance before pregnancy. Besides, strict comprehensive screening of every pregnant mother should be made at antenatal care clinics for early identification and management of antenatal substance use.
Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s) 2021.)
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فهرسة مساهمة: Keywords: Ethiopia; birth outcome; meta-analysis; pregnancy; substance use
تواريخ الأحداث: Date Created: 20210609 Latest Revision: 20210611
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8161854
DOI: 10.1177/2333794X211019699
PMID: 34104698
قاعدة البيانات: MEDLINE
الوصف
تدمد:2333-794X
DOI:10.1177/2333794X211019699