دورية أكاديمية
High-flow nasal cannula failure: can clinical outcomes determine early interruption?
| العنوان: | High-flow nasal cannula failure: can clinical outcomes determine early interruption? |
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| المؤلفون: | Nascimento MS; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Quinto DER; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Zamberlan GC; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Santos AZD; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Rebello CM; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Prado CD; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil. |
| المصدر: | Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2021 Jun 11; Vol. 19, pp. eAO5846. Date of Electronic Publication: 2021 Jun 11 (Print Publication: 2021). |
| نوع المنشور: | Journal Article |
| اللغة: | English; Portuguese |
| بيانات الدورية: | Publisher: Instituto de Ensino e Pesquisa Albert Einstein Country of Publication: Brazil NLM ID: 101281800 Publication Model: eCollection Cited Medium: Internet ISSN: 2317-6385 (Electronic) Linking ISSN: 16794508 NLM ISO Abbreviation: Einstein (Sao Paulo) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, SP : Instituto de Ensino e Pesquisa Albert Einstein |
| مواضيع طبية MeSH: | Bronchiolitis*/therapy , Cannula*, Child ; Humans ; Infant ; Oxygen Inhalation Therapy ; Retrospective Studies |
| مستخلص: | Objective: To evaluate the evolution of clinical outcomes in children with bronchiolitis who used a high-flow nasal cannula, and to determine after long of non-clinical improvement the therapy should be discontinued, and treatment should be escalated to other forms of ventilatory support. Methods: An observational retrospective study of infants with bronchiolitis who used a high-flow nasal cannula. Patients were divided into two study groups according to success or failure of high-flow nasal cannula therapy, namely the Success Group and the Failure Group. The main demographics and clinical variables were assessed 30 minutes and 6 hours after initiating therapy until removal of the high-flow nasal cannula. Results: A total of 83 children were studied and 18 children (21.7%) failed therapy. Among subjects with successful therapy, a significant decrease in respiratory rate (p<0.001), and a significant increase in peripheral oxygen saturation (p<0.001) were observed within 30 minutes. The Success Group was significantly different from the Failure Group after 6 hours, for both respiratory rate (p<0.01) and peripheral oxygen saturation (p<0.01). Conclusion: The absence of clinical sign improvement within 30 minutes and for up to a maximum of 6 hours can be considered as failure of the high-flow nasal cannula therapy. If this time elapses with no improvements, escalating to another type of ventilatory support should be considered. |
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| تواريخ الأحداث: | Date Created: 20210616 Date Completed: 20210618 Latest Revision: 20210626 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8225260 |
| DOI: | 10.31744/einstein_journal/2021AO5846 |
| PMID: | 34133643 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2317-6385 |
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| DOI: | 10.31744/einstein_journal/2021AO5846 |