دورية أكاديمية
أعرض في EDS

Anti-inflammatory Pharmacotherapy for the Prevention of Cystoid Macular Edema After Cataract Surgery.

التفاصيل البيبلوغرافية
العنوان: Anti-inflammatory Pharmacotherapy for the Prevention of Cystoid Macular Edema After Cataract Surgery.
المؤلفون: Taubenslag KJ; From the Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, Tennessee, USA (K.J.T., S.J.K.)., Kim SJ; From the Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, Tennessee, USA (K.J.T., S.J.K.)., Grzybowski A; Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland (A.G.); and Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan, Poland (A.G.). Electronic address: ae.grzybowski@gmail.com.
المصدر: American journal of ophthalmology [Am J Ophthalmol] 2021 Dec; Vol. 232, pp. 1-8. Date of Electronic Publication: 2021 Jun 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : New York, NY : Elsevier Science
Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.]
مواضيع طبية MeSH: Cataract* , Cataract Extraction* , Macular Edema*/diagnosis , Macular Edema*/drug therapy , Macular Edema*/etiology, Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Humans ; Postoperative Complications/drug therapy ; Postoperative Complications/prevention & control
مستخلص: Purpose: To elucidate strategies for and controversies surrounding the use of anti-inflammatory medications after uneventful cataract surgery, with a focus on the prevention of irreversible vision loss due to cystoid macular edema (CME).
Design: Perspective.
Methods: Expert commentary on the management of inflammation after cataract surgery. Discussion includes combination therapy with corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs), dosing strategies, and emerging therapies.
Results: While prescribing both NSAIDs and corticosteroids for cataract surgery is common, these classes have overlapping mechanisms. Combination therapy may speed visual recovery, but there remains little evidence for improved long-term visual outcomes from NSAIDs. The last 2 decades have seen increasing data on potential benefits of pretreatment with NSAIDs 1-3 days prior to cataract surgery. Simultaneously, newly approved "dropless" delivery systems hold promise, and clinical trials are ongoing to assess outcomes of such formulations.
Conclusions: Optimal pharmacologic treatment for inflammation after cataract surgery remains controversial. A consensus definition for clinically significant CME may facilitate the comparison of anti-inflammatory drugs. And there remains a need for well-designed trials examining both topical and extended-release drug-delivery systems to refine the treatment paradigm.
(Copyright © 2021 Elsevier Inc. All rights reserved.)
المشرفين على المادة: 0 (Anti-Inflammatory Agents)
0 (Anti-Inflammatory Agents, Non-Steroidal)
تواريخ الأحداث: Date Created: 20210622 Date Completed: 20220131 Latest Revision: 20220131
رمز التحديث: 20231215
DOI: 10.1016/j.ajo.2021.06.009
PMID: 34157275
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1891
DOI:10.1016/j.ajo.2021.06.009