دورية أكاديمية
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Review of Applications and Future Prospects of Stimuli-Responsive Hydrogel Based on Thermo-Responsive Biopolymers in Drug Delivery Systems.

التفاصيل البيبلوغرافية
العنوان: Review of Applications and Future Prospects of Stimuli-Responsive Hydrogel Based on Thermo-Responsive Biopolymers in Drug Delivery Systems.
المؤلفون: Chatterjee S; Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong., Hui PC; Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
المصدر: Polymers [Polymers (Basel)] 2021 Jun 24; Vol. 13 (13). Date of Electronic Publication: 2021 Jun 24.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101545357 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4360 (Electronic) Linking ISSN: 20734360 NLM ISO Abbreviation: Polymers (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel : MDPI
مستخلص: Some of thermo-responsive polysaccharides, namely, cellulose, xyloglucan, and chitosan, and protein-like gelatin or elastin-like polypeptides can exhibit temperature dependent sol-gel transitions. Due to their biodegradability, biocompatibility, and non-toxicity, such biomaterials are becoming popular for drug delivery and tissue engineering applications. This paper aims to review the properties of sol-gel transition, mechanical strength, drug release (bioavailability of drugs), and cytotoxicity of stimuli-responsive hydrogel made of thermo-responsive biopolymers in drug delivery systems. One of the major applications of such thermos-responsive biopolymers is on textile-based transdermal therapy where the formulation, mechanical, and drug release properties and the cytotoxicity of thermo-responsive hydrogel in drug delivery systems of traditional Chinese medicine have been fully reviewed. Textile-based transdermal therapy, a non-invasive method to treat skin-related disease, can overcome the poor bioavailability of drugs from conventional non-invasive administration. This study also discusses the future prospects of stimuli-responsive hydrogels made of thermo-responsive biopolymers for non-invasive treatment of skin-related disease via textile-based transdermal therapy.
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معلومات مُعتمدة: 1-ZVLM Hong Kong Polytechnic University
فهرسة مساهمة: Keywords: LCST; biopolymer; drug delivery; polysaccharide; thermo-responsive hydrogel; transdermal therapy
تواريخ الأحداث: Date Created: 20210702 Latest Revision: 20210713
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8272167
DOI: 10.3390/polym13132086
PMID: 34202828
قاعدة البيانات: MEDLINE
الوصف
تدمد:2073-4360
DOI:10.3390/polym13132086