دورية أكاديمية
أعرض في EDS

Prebiotics mannan-oligosaccharides accelerate sexual maturity in rats: A randomized preclinical study.

التفاصيل البيبلوغرافية
العنوان: Prebiotics mannan-oligosaccharides accelerate sexual maturity in rats: A randomized preclinical study.
المؤلفون: Rodrigues LE; Department of Functional Sciences, Laboratory of Physiology and Biophysics, Faculty of Medicine, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil., Kishibe MM; Department of Functional Sciences, Laboratory of Physiology and Biophysics, Faculty of Medicine, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil., Keller R; Department of Functional Sciences, Laboratory of Microbiology, Faculty of Biological Sciences, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil., Caetano HRDS; Department of Functional Sciences, Laboratory of Physiology, Faculty of Physiotherapy, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil., Rufino MN; Department of Functional Sciences, Laboratory of Physiology, Faculty of Medicine, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil., Sanches OC; Department of Pathology, Faculty of Veterinary Medicine, Universidade de Santo Amaro, São Paulo, Brazil., Giometti IC; Department of Reproduction, Faculty of Veterinary Medicine, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil., Giuffrida R; Department of Statistics, Faculty of Veterinary Medicine, Universidade do Oeste Paulista, São Paulo, Brazil., Bremer-Neto H; Department of Functional Sciences, Laboratory of Physiology and Biophysics, Faculty of Medicine, Universidade do Oeste Paulista, Presidente Prudente, São Paulo, Brazil.
المصدر: Veterinary world [Vet World] 2021 May; Vol. 14 (5), pp. 1210-1219. Date of Electronic Publication: 2021 May 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Veterinary World Country of Publication: India NLM ID: 101504872 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0972-8988 (Print) Linking ISSN: 09728988 NLM ISO Abbreviation: Vet World Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Dist. Morbi (Gujarat), India : Veterinary World
Original Publication: Rajkot (Gujarat), India : Veterinary World, [2008]-
مستخلص: Background and Aim: The prebiotics, mannan-oligosaccharides (MOS), demonstrate the ability to increase probiotic microorganisms and fixation and removal of pathogens associated with chronic systemic inflammation in the digestive system. Inflammatory processes play an important role in modulating the brain-intestinal axis, including maintaining male reproductive function and spermatogenesis and regulating stress. The aim of the present study was to evaluate the action of MOS on testosterone and corticosterone concentrations and the reproductive system development of rats in the growth phase as an animal model.
Materials and Methods: In total, 128 male rats were used, randomly divided into four experimental groups (n=32): Control; MOS 1; MOS 2; and MOS 3. From each group, eight animals were sacrificed in four experimental moments (14, 28, 42, and 56 days, respectively, moments 1, 2, 3, and 4) and hormonal measurements and histological evaluations were performed.
Results: The results revealed the effect of diet, MOS, and timing on testicle weight (p<0.05). At moments 3 and 4, the groups supplemented with MOS showed higher concentrations of testosterone and decreased corticosterone levels throughout the experimental period. Groups supplemented with MOS showed an increase in the frequency of relative sperm and sperm scores. The radii of the seminiferous tubules presented a significant statistical effect of the diet, moments, and diet + moment interaction.
Conclusion: It was concluded that the three different MOS prebiotics brought forward sexual maturity.
(Copyright: © Rodrigues, et al.)
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فهرسة مساهمة: Keywords: corticosterone; murine; prebiotic; reproductive system; testosterone; yeast
تواريخ الأحداث: Date Created: 20210705 Latest Revision: 20220424
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC8243662
DOI: 10.14202/vetworld.2021.1210-1219
PMID: 34220123
قاعدة البيانات: MEDLINE
الوصف
تدمد:0972-8988
DOI:10.14202/vetworld.2021.1210-1219