دورية أكاديمية
Platelet-leukocyte interactions in the pathogenesis of viral infections.
| العنوان: | Platelet-leukocyte interactions in the pathogenesis of viral infections. |
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| المؤلفون: | Hottz ED; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil.; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Quirino-Teixeira AC; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Merij LB; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Pinheiro MBM; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Rozini SV; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil., Bozza FA; Laboratory of Clinical Research in Intensive Care Medicine, National Institute of Infectious Disease Evandro Chagas, Oswaldo Cruz Foundation, Rio de Janeiro , Brazil.; Intensive Care Medicine, D'Or Institute for Research and Education, Rio de Janeiro, RJ, Brazil., Bozza PT; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. |
| المصدر: | Platelets [Platelets] 2022 Feb 17; Vol. 33 (2), pp. 200-207. Date of Electronic Publication: 2021 Jul 14. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: Edinburgh ; New York : Churchill Livingstone, c1990- |
| مواضيع طبية MeSH: | Blood Platelets/*metabolism , Leukocytes/*metabolism , Virus Diseases/*blood, Humans |
| مستخلص: | Evolving evidence demonstrates that platelets have major roles in viral syndromes through previously unrecognized viral sensing and effector functions. Activated platelets and increased platelet-leukocyte aggregates are observed in clinical and experimental viral infections. The mechanisms and outcomes of platelet-leukocyte interactions depend on the interacting leukocyte as well as on the pathogen and pathological conditions. In this review, we discuss the mechanisms involved in platelet interactions with leukocytes and its functions during viral infections. We focus on the contributions of human platelet-leukocyte interactions to pathophysiological and protective responses during viral infections of major global health relevance, including acquired immunodeficiency syndrome (AIDS), dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), influenza pneumonia, and COVID-19. |
| فهرسة مساهمة: | Keywords: COVID-19; Dengue; HIV; Influenza; platelet-leukocyte aggregates; platelets |
| تواريخ الأحداث: | Date Created: 20210714 Date Completed: 20220228 Latest Revision: 20220228 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/09537104.2021.1952179 |
| PMID: | 34260328 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1369-1635 |
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| DOI: | 10.1080/09537104.2021.1952179 |