The impact of body mass index on left ventricular mass index, right ventricular function, and cardiac dimension of children with sickle cell anemia in Enugu City.

التفاصيل البيبلوغرافية
العنوان:	The impact of body mass index on left ventricular mass index, right ventricular function, and cardiac dimension of children with sickle cell anemia in Enugu City.
المؤلفون:	Chinawa AT; Consultant Community Physician and Lecturer, Enugu State University Teaching Hospital, Enugu State, Nigeria., Chinawa JM; Department of Paediatrics, College of Medicine, University of Nigeria Enugu Campus, Enugu State, Nigeria., Chukwu BF; Consultant Community Physician and Lecturer, Enugu State University Teaching Hospital, Enugu State, Nigeria., Ossai N; Department of community Medicine, College of Health Sciences Ebonyi State University Abakaliki, Nigeria., Ndu IK; Department of Paediatrics, College of Medicine, Enugu State University Teaching hospital, Enugu State, Nigeria., Asinobi IN; Department of Paediatrics, College of Medicine, Enugu State University Teaching hospital, Enugu State, Nigeria., Uwaezuoke NA; Consultant Community Physician and Lecturer, Enugu State University Teaching Hospital, Enugu State, Nigeria.
المصدر:	Nigerian journal of clinical practice [Niger J Clin Pract] 2021 Jul; Vol. 24 (7), pp. 1044-1051.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Medknow Publications Country of Publication: India NLM ID: 101150032 Publication Model: Print Cited Medium: Internet ISSN: 1119-3077 (Print) NLM ISO Abbreviation: Niger J Clin Pract Subsets: MEDLINE
أسماء مطبوعة:	Publication: Mumbai : Medknow Publications Original Publication: [Lagos?] : Medical and Dental Consultants' Association of Nigeria
مواضيع طبية MeSH:	Anemia, Sickle Cell/complications , Anemia, Sickle Cell/epidemiology , Ventricular Function, Right*, Body Mass Index ; Case-Control Studies ; Child ; Female ; Humans ; Male ; Nigeria
مستخلص:	Background: Body mass index is a major determinant of cardiac annular valvar dimension and left ventricular mass index in children with sickle cell anemia. Objectives: The study is aimed at ascertaining the impact of Body Mass Index on Left ventricular mass index, right ventricular function and cardiac dimension of children with sickle cell anemia. Methods: A case control study in which echocardiographic measurement of cardiac function and structures were ascertained among children with sickle cell anemia compared with hemoglobin AA genotype. Results: There were 51 subjects and 50 controls. The subjects comprised 54.9% males and controls, 52.0% male. There was a strong positive correlation between BMI and most cardiac structure diameters among children with normal hemoglobin genotype (Pearson's correlation coefficient value, P < 0.001) There was also statistically significant positive correlation between BMI and LV mass among the subjects (n = 50, r = 0.5, P < 0.001). There was significant positive correlation between BMI and TAPSE in both subjects and controls as well as between BMI and RVSP among the subjects, but not the controls (p < 0.001). There was no significant difference in the number with left ventricular hypertrophy (LVH) based on their nutritional status (n = 51, χ^2 = 7.03, P = 0.32). The BMI correlated negatively with left ventricular mass index (LVMI) among the subjects, but the correlation was not statistically significant (r = -0.1, P = 0.53). Conclusion: There was significant positive correlation between BMI and TAPSE in both subjects and controls as well as between BMI and RVSP among the subjects, but not the controls. Body mass index correlated negatively with left ventricular mass index (LVMI) among the subjects. Competing Interests: None
فهرسة مساهمة:	Keywords: BMI; LVMI; children; echocardiography; sickle cell anemia
تواريخ الأحداث:	Date Created: 20210722 Date Completed: 20210723 Latest Revision: 20220425
رمز التحديث:	20221213
DOI:	10.4103/njcp.njcp_481_20
PMID:	34290181
قاعدة البيانات:	MEDLINE

الوصف
تدمد:	1119-3077
DOI:	10.4103/njcp.njcp_481_20