دورية أكاديمية
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Reusable Nano-Zirconia-Catalyzed Synthesis of Benzimidazoles and Their Antibacterial and Antifungal Activities.

التفاصيل البيبلوغرافية
العنوان: Reusable Nano-Zirconia-Catalyzed Synthesis of Benzimidazoles and Their Antibacterial and Antifungal Activities.
المؤلفون: Rao TN; Department of Chemistry, Krishna University, Machilipatnam 521001, Andhra Pradesh, India., AlOmar SY; Department of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Ahmed F; Department of Physics, College of Science, King Faisal University, Hofuf 31982, Al-Ahsa, Saudi Arabia., Albalawi F; Department of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Ahmad N; Chemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Rao NK; Department of Organic Chemistry, Krishna University, Machilipatnam 521001, Andhra Pradesh, India., Rao MVB; Department of Organic Chemistry, Krishna University, Machilipatnam 521001, Andhra Pradesh, India., Cheedarala RK; Department of Materials Science and Engineering, Ulsan National Institute of Science and Technology, UNIST-Gil, Ulsan 44919, Korea., Reddy GR; Department of Chemical Engineering, A.C Tech Campus, Anna University, Chennai 600025, India., Naidu TM; Department of Nuclear Physics, Andhra University, Visakhapatnam 530003, Andhra Pradesh, India.
المصدر: Molecules (Basel, Switzerland) [Molecules] 2021 Jul 12; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 12.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c1995-
مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Antifungal Agents/*pharmacology , Benzimidazoles/*pharmacology , Catalysis/*drug effects , Nanoparticles/*administration & dosage , Zirconium/*pharmacology
مستخلص: In this article, a zirconia-based nano-catalyst (Nano-ZrO 2 ), with intermolecular C-N bond formation for the synthesis of various benzimidazole-fused heterocycles in a concise method is reported. The robustness of this reaction is demonstrated by the synthesis of a series of benzimidazole drugs in a one-pot method. All synthesized materials were characterized using 1 HNMR, 13 CNMR, and LC-MS spectroscopy as well as microanalysis data. Furthermore, the synthesis of nano-ZrO 2 was processed using a standard hydrothermal technique in pure form. The crystal structure of nano-ZrO 2 and phase purity were studied, and the crystallite size was calculated from XRD analysis using the Debye-Scherrer equation. Furthermore, the antimicrobial activity of the synthesized benzimidazole drugs was evaluated in terms of Gram-positive, Gram-negative, and antifungal activity, and the results were satisfactory.
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فهرسة مساهمة: Keywords: XRD; aryl aldehydes; benzimidazole; nano-ZrO2; o-phenylenediamine
المشرفين على المادة: 0 (Anti-Bacterial Agents)
0 (Antifungal Agents)
0 (Benzimidazoles)
C6V6S92N3C (Zirconium)
E24GX49LD8 (benzimidazole)
S38N85C5G0 (zirconium oxide)
تواريخ الأحداث: Date Created: 20210724 Date Completed: 20210916 Latest Revision: 20240813
رمز التحديث: 20240813
مُعرف محوري في PubMed: PMC8304051
DOI: 10.3390/molecules26144219
PMID: 34299494
قاعدة البيانات: MEDLINE
الوصف
تدمد:1420-3049
DOI:10.3390/molecules26144219