دورية أكاديمية
Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study.
| العنوان: | Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study. |
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| المؤلفون: | Panozzo G; Ophthalmology Unit, Clinica San Francesco, Verona, Italy. g.panozzo@iol.it.; ESASO, European School of Advanced Studies in Ophthalmology, Lugano, Switzerland. g.panozzo@iol.it., Mura GD; ESASO, European School of Advanced Studies in Ophthalmology, Lugano, Switzerland., Franzolin E; Ophthalmology Unit, Department of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy., Giannarelli D; UOSD Clinical Trial Center, Biostatistics and Bioinformatics, Regina Elena National Cancer Institute IRCCS, Rome, Italy., Albano V; Department of Medical Science, Neuroscience and Sense Organs, Eye Clinic, University of Bari, Bari, Italy., Alessio G; Department of Medical Science, Neuroscience and Sense Organs, Eye Clinic, University of Bari, Bari, Italy., Arrigo A; Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Casati S; Ophthalmology Unit, Department of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy., Cassottana P; Department of Ophthalmology, San Martino University Hospital, IRCCS, Genova, Italy., Contardi C; Department of Ophthalmology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., D'Aloisio R; Department of Ophthalmology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Fasce F; Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Gusson E; Ophthalmology Unit, Department of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy., Marchini G; Ophthalmology Unit, Department of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy., Mastropasqua L; Department of Ophthalmology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Niccolò M; Department of Ophthalmology, University of Genova, Genova, Italy., Palmisano C; Department of Medical Science, Neuroscience and Sense Organs, Eye Clinic, University of Bari, Bari, Italy., Pastore MR; Department of Medical Surgical Sciences and Health, Eye Clinic, University of Trieste, Trieste, Italy., Saviano S; Department of Medical Surgical Sciences and Health, Eye Clinic, University of Trieste, Trieste, Italy., Tognetto D; Department of Medical Surgical Sciences and Health, Eye Clinic, University of Trieste, Trieste, Italy., Bandello F; Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Milan, Italy. |
| المصدر: | Eye (London, England) [Eye (Lond)] 2022 Aug; Vol. 36 (8), pp. 1687-1693. Date of Electronic Publication: 2021 Aug 03. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8703986 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5454 (Electronic) Linking ISSN: 0950222X NLM ISO Abbreviation: Eye (Lond) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003->: London : Nature Publishing Group Original Publication: [London : Ophthalmological Society of the United Kingdom, 1987- |
| مواضيع طبية MeSH: | Cataract*/complications , Diabetes Mellitus* , Diabetic Retinopathy*/complications , Diabetic Retinopathy*/surgery , Macular Edema*, Humans ; Prospective Studies ; Tomography, Optical Coherence/methods ; Visual Acuity |
| مستخلص: | Background: The prospective DIabetes and CATaract Study II (DICAT II) was performed to characterise the risks of cataract surgery to the retinae of patients with early diabetic macular oedema (E-DMO). Methods: DICAT II was a prospective, comparative, multicentre, observational study involving six Italian clinics. Patients were aged ≥55 years, had type 1 or 2 diabetes with spectral-domain optical coherence tomography evidence of ESASO classification Early DMO. Group 1 eyes (78 eyes, 78 patients) underwent phacoemulsification-based cataract surgery. Group 2 eyes (65 eyes, 65 patients) had E-DMO and either clear media or had undergone uncomplicated cataract surgery ≥1 year previously. Central subfield thickness (CST) and best-corrected visual acuity (BCVA) were assessed in both groups. Results: The negative impact of surgery on CST was evident after the first postoperative week; CST peaked during the first month, then rapidly decreased. CST worsening ≥10 µm was observed in 63/78 eyes (80.7%) and 29/65 eyes (44.6%) in Groups 1 and 2, respectively (p < 0.0001). CST worsening of ≥50 µm was observed in 51 eyes (65.4%) and 10 eyes (15.4%) in Groups 1 and 2, respectively (p < 0.0001). Mean CST worsening was lower in Group 2 than in Group 1 (38.6 ± 30.4 µm vs 85.5 ± 55.3 µm, p < 0.0001) with a lower BCVA loss (-2.6 ± 3.5 letters vs -8.2 ± 6.2 letters, p < 0.0001). Higher glycaemic levels and HBA1c levels were significantly associated with the risk of >50 μm CST worsening in eyes from both groups. Conclusion: Early DMO is associated with poorer outcomes after cataract surgery and requires close pre- and postoperative monitoring. (© 2021. The Author(s), under exclusive licence to The Royal College of Ophthalmologists.) |
| References: | International Diabetes Federation. IDF Diabetes Atlas Ninth Edition. https://www.diabetesatlas.org/upload/resources/material/20200302_133351_IDFATLAS9e-final-web.pdf (2019). Accessed 20 June 2021. Selvin E, Coresh J, Brancati FL. The burden and treatment of diabetes in elderly individuals in the U.S. Diabetes Care. 2006;29:2415–9. (PMID: 10.2337/dc06-1058) Wang Q, Zhang X, Fang L, Guan Q, Guan L, Li Q. Prevalence, awareness, treatment and control of diabetes mellitus among middle-aged and elderly people in a rural Chinese population: a cross-sectional study. PLoS One. 2018;13:e0198343. (PMID: 10.1371/journal.pone.0198343) Pollreisz A, Schmidt-Erfurth U. Diabetic cataract-pathogenesis, epidemiology and treatment. J Ophthalmol. 2010;2010:608751. (PMID: 206349362903955) International Diabetes Federation. Clinical practice recommendations for managing diabetic macular edema. https://www.idf.org/component/attachments/?task=download&id=2153 (2019). Accessed 20 June 2021. Shin ES, Sorenson CM, Sheibani N. Diabetes and retinal vascular dysfunction. J Ophthalmic Vis Res. 2014;9:362–73. (PMID: 256677394307665) Panozzo G, Staurenghi G, Dalla Mura G, Giannarelli D, Alessio G, Alongi S, et al. Prevalence of diabetes and diabetic macular edema in patients undergoing senile cataract surgery in Italy: The DIabetes and CATaract study. Eur J Ophthalmol. 2020;30:315–20. (PMID: 10.1177/1120672119830578) Dowler JG, Hykin PG, Lightman SL, Hamilton AM. Visual acuity following extracapsular cataract extraction in diabetes: a meta-analysis. Eye (Lond). 1995;9:313–7. Pt 3. (PMID: 10.1038/eye.1995.61) Gupta A, Gupta V. Diabetic maculopathy and cataract surgery. Ophthalmol Clin North Am. 2001;14:625–37. (PMID: 10.1016/S0896-1549(05)70262-5) Chu CJ, Johnston RL, Buscombe C, Sallam AB, Mohamed Q, Yang YC. Risk factors and incidence of macular edema after cataract surgery: a database study of 81984 eyes. Ophthalmology. 2016;123:316–23. (PMID: 10.1016/j.ophtha.2015.10.001) Panozzo G, Cicinelli MV, Augustin AJ, Battaglia Parodi M, Cunha-Vaz J, Guarnaccia G, et al. An optical coherence tomography-based grading of diabetic maculopathy proposed by an international expert panel: The European School for Advanced Studies in Ophthalmology classification. Eur J Ophthalmol. 2020;30:8–18. (PMID: 10.1177/1120672119880394) ETDRS Group. Grading diabetic retinopathy from stereoscopic color fundus photographs—an extension of the modified airlie house classification: ETDRS Report Number 10. Ophthalmol. 1991;98:786–806. (PMID: 10.1016/S0161-6420(13)38012-9) Yüksel B, Karti Ö, Kusbeci T. Topical nepafenac for prevention of post-cataract surgery macular edema in diabetic patients: patient selection and perspectives. Clin Ophthalmol. 2017;11:2183–90. (PMID: 10.2147/OPTH.S132810) Furino C, Boscia F, Niro A, D’Addario M, Grassi MO, Saglimbene V, et al. Diabetic macular edema and cataract surgery: phacoemulsification combined with dexamethasone intravitreal implant compared with standard phacoemulsification. Retina. 2021;41:1102–9. (PMID: 10.1097/IAE.0000000000002974) Rauen PI, Ribeiro JA, Almeida FP, Scott IU, Messias A, Jorge R. Intravitreal injection of ranibizumab during cataract surgery in patients with diabetic macular edema. Retina. 2012;32:1799–803. (PMID: 10.1097/IAE.0b013e31824bebb8) Goh JKS, Lim LL. Dealing with co-existent cataract and diabetic macular oedema: an increasingly common conundrum now solved? Clin Exp Ophthalmol. 2020;48:424–6. (PMID: 10.1111/ceo.13764) Baker CW, Almukhtar T, Bressler NM, Glassman AR, Grover S, Kim SJ, et al. Macular edema after cataract surgery in eyes without preoperative central-involved diabetic macular edema. JAMA Ophthalmol. 2013;131:870–9. (PMID: 10.1001/jamaophthalmol.2013.2313) Chen XY, Song WJ, Cai HY, Zhao L. Macular edema after cataract surgery in diabetic eyes evaluated by optical coherence tomography. Int J Ophthalmol. 2016;9:81–5. (PMID: 10.17816/OV9281-99) Bressler SB, Baker CW, Almukhtar T, Bressler NM, Edwards PA, Glassman AR, et al. Pilot study of individuals with diabetic macular edema undergoing cataract surgery. JAMA Ophthalmol. 2014;132:224–6. (PMID: 10.1001/jamaophthalmol.2013.6209) |
| تواريخ الأحداث: | Date Created: 20210804 Date Completed: 20220726 Latest Revision: 20221122 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8330474 |
| DOI: | 10.1038/s41433-021-01718-4 |
| PMID: | 34345028 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1476-5454 |
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| DOI: | 10.1038/s41433-021-01718-4 |