دورية أكاديمية
Mechanism of preservation of the intestinal mucosa architecture and NF-κB/PGE2 reduction by hydrogen sulfide on cholera toxin-induced diarrhea in mice.
العنوان: | Mechanism of preservation of the intestinal mucosa architecture and NF-κB/PGE2 reduction by hydrogen sulfide on cholera toxin-induced diarrhea in mice. |
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المؤلفون: | Sousa FBM; Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (LAFIDG), Post-graduation Program in Biotechnology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil; Northeast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, PI, Brazil., Pacheco G; Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (LAFIDG), Post-graduation Program in Biotechnology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil., Oliveira AP; Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (LAFIDG), Post-graduation Program in Biotechnology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil; Northeast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, PI, Brazil., Nicolau LAD; Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (LAFIDG), Post-graduation Program in Biotechnology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil., Lopes ALF; Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (LAFIDG), Post-graduation Program in Biotechnology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil., Ferreira-Fernandes H; Laboratory of Genetics and Molecular Biology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil., Pinto GR; Northeast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, PI, Brazil; Laboratory of Genetics and Molecular Biology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil., Medeiros JVR; Laboratory of Pharmacology of Inflammation and Gastrointestinal Disorders (LAFIDG), Post-graduation Program in Biotechnology, Parnaiba Delta Federal University, Parnaíba, PI, Brazil; Northeast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, PI, Brazil. Electronic address: jandvenes@ufpi.edu.br. |
المصدر: | Life sciences [Life Sci] 2021 Nov 01; Vol. 284, pp. 119869. Date of Electronic Publication: 2021 Aug 03. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2008->: Amsterdam : Elsevier Original Publication: Oxford; Elmsford, N. Y. [etc.] Pergamon Press. |
مواضيع طبية MeSH: | Diarrhea/*chemically induced , Diarrhea/*metabolism , Dinoprostone/*metabolism , Hydrogen Sulfide/*pharmacology , Intestinal Mucosa/*pathology , NF-kappa B/*metabolism, Animals ; Cholera Toxin ; Female ; Gene Expression Profiling ; Male ; Mice ; Morpholines/pharmacology ; Organothiophosphorus Compounds/pharmacology ; Receptors, Prostaglandin E, EP2 Subtype/metabolism ; Receptors, Prostaglandin E, EP4 Subtype/metabolism |
مستخلص: | Aims: Investigate the involvement of Hydrogen sulfide (H Main Methods: Mice were subjected to the procedure of inducing diarrhea by CT in the isolated intestinal loop model. The intestinal loops were inoculated with H Key Findings: H Significance: Our results point to a protective activity of H (Copyright © 2021 Elsevier Inc. All rights reserved.) |
فهرسة مساهمة: | Keywords: Cholera; Hydrogen sulfide; Intestinal morphometry; NF-κB |
المشرفين على المادة: | 0 (GYY 4137) 0 (Morpholines) 0 (NF-kappa B) 0 (Organothiophosphorus Compounds) 0 (Receptors, Prostaglandin E, EP2 Subtype) 0 (Receptors, Prostaglandin E, EP4 Subtype) 9012-63-9 (Cholera Toxin) K7Q1JQR04M (Dinoprostone) YY9FVM7NSN (Hydrogen Sulfide) |
تواريخ الأحداث: | Date Created: 20210806 Date Completed: 20211007 Latest Revision: 20211007 |
رمز التحديث: | 20221213 |
DOI: | 10.1016/j.lfs.2021.119869 |
PMID: | 34358552 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1879-0631 |
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DOI: | 10.1016/j.lfs.2021.119869 |