دورية أكاديمية
[The Diagnostic Value of Peripheral Blood Cell Parameters for Early Recognition of Myelodysplastic Syndrome].
العنوان: | [The Diagnostic Value of Peripheral Blood Cell Parameters for Early Recognition of Myelodysplastic Syndrome]. |
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المؤلفون: | Liang HP; Department of Hematology ,The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China., Wang Y; Department of Hematology ,The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China E-mail: wangying730@126.com., Li D; Department of Hematology ,The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China., Zhang LL; Department of Hematology ,The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China., Wu C; Department of Hematology ,The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China., Ren JH; Department of Hematology ,The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China E-mail: jinhai1966@sina.cn. |
المصدر: | Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Aug; Vol. 29 (4), pp. 1231-1235. |
نوع المنشور: | Journal Article |
اللغة: | Chinese |
بيانات الدورية: | Publisher: Zhongguo shi yan xue za zhi she Country of Publication: China NLM ID: 101084424 Publication Model: Print Cited Medium: Print ISSN: 1009-2137 (Print) Linking ISSN: 10092137 NLM ISO Abbreviation: Zhongguo Shi Yan Xue Ye Xue Za Zhi Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Beijing : Zhongguo shi yan xue za zhi she, |
مواضيع طبية MeSH: | Lymphocytes* , Myelodysplastic Syndromes*/diagnosis, Humans ; Leukocyte Count ; Platelet Count ; Retrospective Studies |
مستخلص: | Objective: To evaluate the diagnostic value of peripheral blood cell parameters for early recognition of myelodysplastic syndrome (MDS) patients. Methods: The clinical and laboratory data of 86 patients with MDS and 72 patients with non-malignant clonal anemia treated in first diagnosed in the Second Hospital of Hebei Medical University from January 1, 2015 to December 31, 2017 was retrospectively analyzed. The peripheral blood cell parameters of the patients in two groups were analyzed, generated the receiver operator characteristic curve (ROC curve) from the statistically significant parameters, the binary logistic model was build to calculate and compare the area under the ROC curve (AUC) combined with multiple indicators and individual indicators, sensitivity, specificity, positive and negative likelihood ratio, and diagnostic accuracy, the diagnostic efficacy of the patients was analyzed. Results: Compared with patients in the non-malignant clonal anemia group ,white blood cell count (WBC), neutrophil percentage (NE%), eosinophil percentage (E%), eosinophil absolute value (E#), platelet count (PLT), platelet specific volume (PCT%) in the MDS patients were significantly reduced; while percentage of lymphocytes (LY%), basophilic percentage (B%), and the width of platelet distribution (PDW) significantly increased. The several ROC curves with the above indicators were established, which showed that AUC Conclusion: PDW, B% and LY% in peripheral blood cell parameters have certain diagnostic value for early recognition of MDS. |
فهرسة مساهمة: | Local Abstract: [Publisher, Chinese] 外周血细胞参数对早期识别骨髓增生异常综合征患者诊断价值的研究. [Publisher, Chinese] 评估外周血细胞参数对早期识别骨髓增生异常综合征(MDS)患者的诊断价值。. [Publisher, Chinese] 回顾性选取2015年1月1日至2017年12月31日首诊于河北医科大学第二医院的MDS患者86例和非恶性克隆性贫血患者72例的临床及实验室检查数据,比较分析两组患者的外周血细胞参数,将有统计学差异的参数制作出受试者工作特性曲线(receiver operator characteristic curve,ROC curve),并建立二元Logistic模型,分别计算并比较联合多个及单个指标的ROC曲线下面积(AUC)和灵敏度、特异度、阳阴性似然比及诊断正确率以评估其诊断效能。. [Publisher, Chinese] 与非恶性克隆性贫血组患者相比,MDS组患者的白细胞数(WBC)、中性粒细胞百分比(NE%)、嗜酸性粒细胞百分比(E%)、嗜酸性粒细胞绝对值(E#)、血小板计数(PLT)、血小板比容(PCT%)明显减低,而淋巴细胞百分比(LY%)、嗜碱性粒细胞百分比(B%)、血小板分布宽度(PDW)明显升高。将上述指标制作成ROC曲线,AUC大于0.5的有AUC |
تواريخ الأحداث: | Date Created: 20210807 Date Completed: 20210810 Latest Revision: 20210810 |
رمز التحديث: | 20231215 |
DOI: | 10.19746/j.cnki.issn.1009-2137.2021.04.032 |
PMID: | 34362507 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1009-2137 |
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DOI: | 10.19746/j.cnki.issn.1009-2137.2021.04.032 |