دورية أكاديمية
Preoperative monocytosis is predictable at diagnosis for RT-PCR negative COVİD-19 paediatric cardiac surgery patients.
| العنوان: | Preoperative monocytosis is predictable at diagnosis for RT-PCR negative COVİD-19 paediatric cardiac surgery patients. |
|---|---|
| المؤلفون: | Arslanoğlu E; Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey., Işık ME; Microbiology and Infectious Diseases Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey., Kara KA; Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey., Yigit F; Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey., Çine N; Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey., Tunçer E; Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey., Ceyran H; Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey. |
| المصدر: | Cardiology in the young [Cardiol Young] 2022 Jun; Vol. 32 (6), pp. 883-887. Date of Electronic Publication: 2021 Aug 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cambridge University Press Country of Publication: England NLM ID: 9200019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-1107 (Electronic) Linking ISSN: 10479511 NLM ISO Abbreviation: Cardiol Young Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005->: Cambridge : Cambridge University Press Original Publication: Chapel Hill, NC : World Publishers, c1991- |
| مواضيع طبية MeSH: | COVID-19*/diagnosis , Cardiac Surgical Procedures*/methods , Lymphopenia*, Adult ; Child ; Humans ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2/genetics |
| مستخلص: | Other markers investigated in this population have gained importance in the diagnosis of the disease since the course of COVID-19 disease is atypical in the paediatric population and PCR may be misleading. The leukocyte profile is one of these biochemical tests. Children did not have lymphopenia in hemogram count, whereas relatively neutropenia and monocytosis were detected, unlike the adult population. The reason why children do not have lymphopenia is thought to be due to the fact that the thymus is more active in the first years of life.Two-hundred and four patients operated in our paediatric cardiac surgery clinic from 11March, 2020 to 1 April, 2021 were retrospectively examined and 11 patients with preoperative asymptomatic and PCR (-), but with PCR (+) in the post-operative period (patients with incubation period or false PCR negativity) were included in our study. Patients requiring emergency operation and operated from PCR (+) patients in the preoperative period were excluded from the study.The neutrophil ratio in the lymphocytic series of 7 patients out of 11 patients was slightly below the normal range in the preoperative period, the lymphocyte ratio of 3 patients was slightly above the normal range, and the relative monocyte ratio of 10 patients was slightly above the normal range.We think that evaluating the leukocyte profile combined with RT-PCR will give more accurate results in the diagnosis of incubation period and false RT-PCR negative patients. In addition, we believe that the algorithms for non-complex paediatric cardiac surgery procedures and timing in the paediatric population with a better course of COVID-19 disease with a positive post-operative course. |
| فهرسة مساهمة: | Keywords: COVID-19; Leukocyte profile; paediatric cardiac surgery; relative monocyte |
| تواريخ الأحداث: | Date Created: 20210809 Date Completed: 20220616 Latest Revision: 20220616 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1017/S104795112100319X |
| PMID: | 34365984 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1467-1107 |
|---|---|
| DOI: | 10.1017/S104795112100319X |