دورية أكاديمية

Dietary Intake of Flaxseed Oil since Early Stages of Life Promotes Femur Quality in Male Rats.

التفاصيل البيبلوغرافية
العنوان: Dietary Intake of Flaxseed Oil since Early Stages of Life Promotes Femur Quality in Male Rats.
المؤلفون: Pereira AD; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Ribeiro DC; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Cardoso LMDF; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Ribeiro GG; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Quintes BDCR; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Boueri BFDC; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Costa NDS; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Chagas M; Laboratory of Cellular and Extracellular Biomorphology, Federal Fluminense University, Niterói, Rio de Janeiro, Brazil., Silva EMD; Analytical Laboratory of Restorative Biomaterials, Dental School, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., da Costa CAS; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.; Health and Science Center, Federal University Reconcavo of Bahia, Santo Antonio de Jesus, Bahia, Brazil., Velarde LGC; Department of Statistics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil., Boaventura GT; Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
المصدر: Journal of the American Nutrition Association [J Am Nutr Assoc] 2022 Jul; Vol. 41 (5), pp. 462-467. Date of Electronic Publication: 2021 Aug 09.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 9918300687506676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2769-707X (Electronic) Linking ISSN: 27697061 NLM ISO Abbreviation: J Am Nutr Assoc Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Philadelphia, Pennsylvania?] : Taylor & Francis Group, [2022]-
مواضيع طبية MeSH: Diet*/veterinary , Femur*/diagnostic imaging , Linseed Oil*, Animals ; Male ; Osteocalcin ; Rats ; Rats, Wistar
مستخلص: Background: Flaxseed oil (FO) is an alpha linolenic acid source important for growth and body development. However, there is little literature on the role of FO in critical stages of bone development and formation.
Objective: This study evaluated the influence of a diet containing FO on rat femurs.
Methods: After birth, mothers and pups were divided into control and flaxseed groups (n = 6 pups each) fed diets containing 7% soybean oil (C) or 7% FO. At 21 days, pups were weaned and separated from the mothers, and control or experimental diets were continued. At 67 days, the following were analyzed: osteocalcin and osteoprotegerin (OPG) levels, bone mineral density (BMD) and content, and bone area; the dimension, BMD, head radiodensity, and biomechanical proprieties of the right femur; and histomorphometric parameters of the left femur.
Results: Compared to the C group, the FO group presented ( p  < 0.05) a lower body mass (-3.7%) and medullary area (-10.1%) and higher osteocalcin (+36.7%), OPG (+52.5%), femur width (+3.8%), absolute mass (+2.3%), femur BMD (+3.6%), head radiodensity (+6.1%), maximum force (+7.4%), breaking strength (+17.3), and cortical thickness (+7.0).
Conclusion: The FO diet contributed to femur quality in healthy male Wistar rats.
فهرسة مساهمة: Keywords: dual-energy X-ray absorptiometry; femur; flaxseed oil; rats
المشرفين على المادة: 104982-03-8 (Osteocalcin)
8001-26-1 (Linseed Oil)
تواريخ الأحداث: Date Created: 20210809 Date Completed: 20220721 Latest Revision: 20221221
رمز التحديث: 20240628
DOI: 10.1080/07315724.2021.1912673
PMID: 34370629
قاعدة البيانات: MEDLINE
الوصف
تدمد:2769-707X
DOI:10.1080/07315724.2021.1912673