دورية أكاديمية
أعرض في EDS

Perspectives of bilateral thoracic sympathectomy for treatment of heart failure.

التفاصيل البيبلوغرافية
العنوان: Perspectives of bilateral thoracic sympathectomy for treatment of heart failure.
المؤلفون: Coutinho E Silva RDS; Laboratorio Cirurgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coracao (Incor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., Zanoni FL; Laboratorio Cirurgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coracao (Incor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., Simas R; The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Stockholm, Sweden., Moreira LFP; Laboratorio Cirurgico de Pesquisa Cardiovascular (LIM-11), Instituto do Coracao (Incor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
المصدر: Clinics (Sao Paulo, Brazil) [Clinics (Sao Paulo)] 2021 Aug 04; Vol. 76, pp. e3248. Date of Electronic Publication: 2021 Aug 04 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101244734 Publication Model: eCollection Cited Medium: Internet ISSN: 1980-5322 (Electronic) Linking ISSN: 18075932 NLM ISO Abbreviation: Clinics (Sao Paulo) Subsets: MEDLINE
أسماء مطبوعة: Publication: 2022- : [New York] : Elsevier
Original Publication: São Paulo, SP : Hospital das Clínicas, Faculty of Medicine, University of São Paulo, [2005]-
مواضيع طبية MeSH: Heart Failure*/surgery , Hyperhidrosis*/surgery , Thoracic Surgical Procedures*, Humans ; Sympathectomy ; Treatment Outcome
مستخلص: Surgical neuromodulation therapies are still considered a last resort when standard therapies have failed for patients with progressive heart failure (HF). Although a number of experimental studies have provided robust evidence of its effectiveness, the lack of strong clinical evidence discourages practitioners. Thoracic unilateral sympathectomy has been extensively studied and has failed to show significant clinical improvement in HF patients. Most recently, bilateral sympathectomy effect was associated with a high degree of success in HF models, opening the perspective to be investigated in randomized controlled clinical trials. In addition, a series of clinical trials showed that bilateral sympathectomy was associated with a decreased risk of sudden death, which is an important outcome in patients with HF. These aspects indicates that bilateral sympathectomy could be an important alternative in the treatment of HF wherein pharmacological treatment barely reaches the target dose.
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تواريخ الأحداث: Date Created: 20210811 Date Completed: 20210927 Latest Revision: 20220629
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC8311637
DOI: 10.6061/clinics/2021/e3248
PMID: 34378733
قاعدة البيانات: MEDLINE
الوصف
تدمد:1980-5322
DOI:10.6061/clinics/2021/e3248