دورية أكاديمية

A systematic review of quantitative analysis of cannabinoids in oral fluid.

التفاصيل البيبلوغرافية
العنوان: A systematic review of quantitative analysis of cannabinoids in oral fluid.
المؤلفون: Gorziza RP; Department of Pharmacy, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Duarte JA; Department of Pharmacy, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., González M; Department of Pharmacy, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Arroyo-Mora LE; Department of Forensic and Investigative Science, West Virginia University, Morgantown, West Virginia, USA., Limberger RP; Department of Forensic and Investigative Science, West Virginia University, Morgantown, West Virginia, USA.
المصدر: Journal of forensic sciences [J Forensic Sci] 2021 Nov; Vol. 66 (6), pp. 2104-2112. Date of Electronic Publication: 2021 Aug 18.
نوع المنشور: Journal Article; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Blackwell Pub Country of Publication: United States NLM ID: 0375370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-4029 (Electronic) Linking ISSN: 00221198 NLM ISO Abbreviation: J Forensic Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: 2006- : Malden, MA : Blackwell Pub.
Original Publication: [Chicago, Ill.] : Callaghan and Co., 1956-
مواضيع طبية MeSH: Cannabinoids/*analysis , Saliva/*chemistry , Substance Abuse Detection/*methods, Chromatography, Gas ; Chromatography, Liquid ; Forensic Toxicology/methods ; Humans ; Liquid-Liquid Extraction ; Mass Spectrometry ; Solid Phase Extraction
مستخلص: Cannabis sativa L. is a substance widely used around the world for recreational and medicinal purposes. Oral fluid has been investigated as an alternative biological matrix for demonstrating the illegal use of cannabis, particularly in situations where its recent use needs to be identified. In the last two decades, many methods have been developed to detect and quantify cannabinoids in oral fluid, especially for Δ 9 -tetrahydrocannabinol, the primary psychoactive substance of cannabis. However, some aspects must be considered in the use of these techniques, such as cannabinoids recoveries or extraction efficiency from different oral fluid collection devices/containers. Pharmacokinetic studies have shown that the presence of minor cannabinoids and metabolites in the analysis of oral fluid may be valuable in interpreting tests, which indicates the need to improve the sensitivity of detecting low concentrations. The aim of this review is to summarize and to describe the methodologies for the quantitative analysis of cannabinoids in oral fluid that have previously been investigated. A systematic search for articles was performed of four different databases, using the descriptor "cannabinoids and oral fluid". Forty-seven studies that examined quantitative methods were identified. The analytical data described in these articles, including oral fluid collection, sample preparation, cannabinoids recovery and extraction efficiency, detection instruments, and quantification limits, were analyzed. The discussion of these particular features of cannabinoid analysis in oral fluid could help to improve or to develop methods for use in Forensic Toxicology.
(© 2021 American Academy of Forensic Sciences.)
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معلومات مُعتمدة: 23038.006845/2014-91 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
فهرسة مساهمة: Keywords: THC; cannabinoids; cannabis; forensic toxicology; oral fluid; quantitative analysis
المشرفين على المادة: 0 (Cannabinoids)
تواريخ الأحداث: Date Created: 20210818 Date Completed: 20211118 Latest Revision: 20211118
رمز التحديث: 20240628
DOI: 10.1111/1556-4029.14862
PMID: 34405898
قاعدة البيانات: MEDLINE
الوصف
تدمد:1556-4029
DOI:10.1111/1556-4029.14862