دورية أكاديمية
أعرض في EDS

Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology.

التفاصيل البيبلوغرافية
العنوان: Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology.
المؤلفون: Egbuna C; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR), Nutritional Biochemistry and Toxicology Unit, University of Port-Harcourt, Port Harcourt, Rivers State, Nigeria.; Department of Biochemistry, Faculty of Science, University of Port Harcourt, East-West Road, P.M.B 5323, Port Harcourt, Rivers State, Nigeria.; Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State 431124, Nigeria., Parmar VK; Department of Pharmaceutical Sciences, Sardar Patel University, Vallabh Vidyanagar - 388 120, Gujarat, India., Jeevanandam J; CQM-Centro de Química da Madeira, MMRG, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal., Ezzat SM; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El Ainy Street, 11562 Cairo, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6th of October 12566, Egypt., Patrick-Iwuanyanwu KC; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR), Nutritional Biochemistry and Toxicology Unit, University of Port-Harcourt, Port Harcourt, Rivers State, Nigeria.; Department of Biochemistry, Faculty of Science, University of Port Harcourt, East-West Road, P.M.B 5323, Port Harcourt, Rivers State, Nigeria., Adetunji CO; Applied Microbiology, Biotechnology and Nanotechnology Laboratory, Department of Microbiology, Edo University Iyamho, PMB 04 Auchi, Edo State, Nigeria., Khan J; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah 11952, Saudi Arabia.; Health and Basic Sciences Research Center, Majmaah University, Majmaah 11952, Saudi Arabia., Onyeike EN; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR), Nutritional Biochemistry and Toxicology Unit, University of Port-Harcourt, Port Harcourt, Rivers State, Nigeria.; Department of Biochemistry, Faculty of Science, University of Port Harcourt, East-West Road, P.M.B 5323, Port Harcourt, Rivers State, Nigeria., Uche CZ; Department of Medical Biochemistry and Molecular Biology, Faculty of Basic Medical Sciences, University of Nigeria, Enugu Campus, Nsukka, Nigeria., Akram M; Department of Eastern Medicines, Government College University, Faisalabad, Pakistan., Ibrahim MS; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6th of October 12566, Egypt., El Mahdy NM; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 6th of October 12566, Egypt., Awuchi CG; School of Natural and Applied Sciences, Kampala International University, Kampala, Uganda., Saravanan K; PG and Research Department of Zoology, Nehru Memorial College (Autonomous), Puthanampatti-621 007, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India., Tijjani H; Department of Biochemistry, Natural Product Research Laboratory, Bauchi State University, Gadau, Nigeria., Odoh UE; Department of Pharmacognosy and Environmental Medicines, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria., Messaoudi M; Nuclear Research Centre of Birine, Ain Oussera, P.O. Box 180, Djelfa 17200, Algeria.; Chemistry Department, University of Hamma Lakhdar, B.P. 789, El-Oued 39000, Algeria., Ifemeje JC; Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State 431124, Nigeria., Olisah MC; Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State 431124, Nigeria., Ezeofor NJ; Department of Food Technology, School of Applied Science and Technology, Federal Polytechnic, Oko, Anambra State, Nigeria., Chikwendu CJ; Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State 431124, Nigeria., Ibeabuchi CG; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR), Nutritional Biochemistry and Toxicology Unit, University of Port-Harcourt, Port Harcourt, Rivers State, Nigeria.; Department of Biochemistry, Faculty of Science, University of Port Harcourt, East-West Road, P.M.B 5323, Port Harcourt, Rivers State, Nigeria.
المصدر: Journal of toxicology [J Toxicol] 2021 Jul 30; Vol. 2021, pp. 9954443. Date of Electronic Publication: 2021 Jul 30 (Print Publication: 2021).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: Egypt NLM ID: 101519097 Publication Model: eCollection Cited Medium: Print ISSN: 1687-8191 (Print) Linking ISSN: 16878191 NLM ISO Abbreviation: J Toxicol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Cairo, Egypt] : Hindawi Pub. Corp., 2008-
مستخلص: Nanoparticles are of great importance in development and research because of their application in industries and biomedicine. The development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target, compatibility, and functions. This review presents a comprehensive update on nanoparticles' toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. Recent studies have found that nanoparticles may cause serious health effects when exposed to the body through ingestion, inhalation, and skin contact without caution. The extent to which toxicity is induced depends on some properties, including the nature and size of the nanoparticle, the surface area, shape, aspect ratio, surface coating, crystallinity, dissolution, and agglomeration. In all, the general mechanisms by which it causes toxicity lie on its capability to initiate the formation of reactive species, cytotoxicity, genotoxicity, and neurotoxicity, among others.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2021 Chukwuebuka Egbuna et al.)
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تواريخ الأحداث: Date Created: 20210823 Latest Revision: 20210824
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8376461
DOI: 10.1155/2021/9954443
PMID: 34422042
قاعدة البيانات: MEDLINE
الوصف
تدمد:1687-8191
DOI:10.1155/2021/9954443