دورية أكاديمية
Multidrug resistance to commonly prescribed antibiotics in Escherichia coli isolated from barbecued beef ( Suya ) sold in a Nigerian City.
| العنوان: | Multidrug resistance to commonly prescribed antibiotics in Escherichia coli isolated from barbecued beef ( Suya ) sold in a Nigerian City. |
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| المؤلفون: | Datok DW; Department of Microbiology, Nasarawa State University, Keffi, Nigeria.; Standards Organisation of Nigeria (SON), Federal Capital Territory (FCT) Office, Wuse Zone 4, Abuja, Nigeria., Ishaleku D; Department of Microbiology, Nasarawa State University, Keffi, Nigeria., Tsaku PA; Department of Microbiology, Nasarawa State University, Keffi, Nigeria., Agya EO; Department of Microbiology, Nasarawa State University, Keffi, Nigeria., Adoga MP; Department of Microbiology, Nasarawa State University, Keffi, Nigeria. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2021 May 19; Vol. 39, pp. 50. Date of Electronic Publication: 2021 May 19 (Print Publication: 2021). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Anti-Bacterial Agents/*pharmacology , Escherichia coli/*drug effects , Red Meat/*microbiology, Animals ; Cattle ; Drug Resistance, Multiple, Bacterial ; Escherichia coli/isolation & purification ; Microbial Sensitivity Tests ; Nigeria |
| مستخلص: | Introduction: Suya, a form of barbecued meat widely consumed in Nigeria is a rising source of concern for the dissemination of pathogens and antibiotic resistance. Methods: this study was carried out to determine the antibiotic resistance profile of Escherichia coli (E. coli) isolated from Suya sold in Karu Local Government Area, Nasarawa State, Nigeria. A total of three hundred (300) Suya samples were collected and screened for the presence of E. coli. An antibiotic susceptibility study was carried out on the isolated bacteria to determine their resistance profiles. Results: the overall isolation and occurrence of E. coli was 13.3%. The isolated organisms were most resistant to Ampicillin (100%) followed by Amoxicillin/Clavulanic acid (95%), Ciprofloxacin (92.5%), Nitrofurantoin, Imipenem and Ceftriaxone (85%), Cefixime (80%), Streptomycin (77.5%), and Cotrimoxazole (77%), with a low level of resistance recorded against Gentamycin (5%). Most of the E. coli isolates had multiple resistance (MAR) to at least five antibiotics (MAR Index of = 0.5) and the most frequent MAR Index was 0.8 with 37.5% occurrence. The most frequently encountered resistance phenotype was Nitrofurantoin-Imipenem-Streptomycin-Ciprofloxacin-Ceftriaxone-Amoxicillin/clavulanic acid-Cefixime-Ampicillin. The E. coli isolates categorised based on drug resistance classes were Multi-Drug Resistance, MDR (97.5%), Pan Drug Resistance, PDR (2.5%), Non-Multi-Drug Resistance, NMDR (0.0%) and Extensive Drug Resistance, XDR (0.0%). Conclusion: these findings indicate a potential danger of multidrug resistant organisms in circulation. Antibiotics stewardship and drug resistance surveillance is strongly recommended for all stakeholders. Competing Interests: The authors declare no competing interests. (Copyright: Danladi Walong Datok et al.) |
| References: | Pan Afr Med J. 2019 Jul 17;33:219. (PMID: 31692780) Int J Environ Res Public Health. 2012 Aug;9(8):2608-19. (PMID: 23066386) Sci Rep. 2018 Aug 27;8(1):12926. (PMID: 30150710) Lett Appl Microbiol. 1997 Mar;24(3):169-71. (PMID: 9080693) J Food Prot. 2005 Feb;68(2):403-6. (PMID: 15726987) Appl Environ Microbiol. 1983 Jul;46(1):165-70. (PMID: 6351743) Heliyon. 2019 Aug 01;5(8):e02177. (PMID: 31406939) Scientifica (Cairo). 2016;2016:4602036. (PMID: 27092289) |
| فهرسة مساهمة: | Keywords: Drug resistance; Escherichia coli; Nigeria; Suya; hygiene; public health |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20210823 Date Completed: 20210902 Latest Revision: 20220426 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC8356927 |
| DOI: | 10.11604/pamj.2021.39.50.25502 |
| PMID: | 34422173 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2021.39.50.25502 |